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Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–priva...

Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–priva...

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7401349

Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–private drug discovery institute collaboration

About this item

Full title

Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–private drug discovery institute collaboration

Publisher

Cary: Society for the Study of Reproduction

Journal title

Biology of reproduction, 2020-08, Vol.103 (2), p.176-182

Language

English

Formats

Publication information

Publisher

Cary: Society for the Study of Reproduction

More information

Scope and Contents

Contents

Efforts to develop new male or female nonhormonal, orally available contraceptives assume that to be effective and safe, targets must be (1) essential for fertility; (2) amenable to targeting by small-molecule inhibitors; and (3) restricted to the germline. In this perspective, we question the third assumption and propose that despite its wide expr...

Alternative Titles

Full title

Optimization of lead compounds into on-demand, nonhormonal contraceptives: leveraging a public–private drug discovery institute collaboration

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7401349

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7401349

Other Identifiers

ISSN

0006-3363

E-ISSN

1529-7268

DOI

10.1093/biolre/ioaa052

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