Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis
Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis
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Author / Creator
Li, Peishan , Lu, Ming , Shi, Jiayuan , Gong, Zheng , Hua, Li , Li, Qing , Lim, Bora , Zhang, Xiang H.-F. , Chen, Xiaowen , Li, Sheng , Shultz, Leonard D. and Ren, Guangwen
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
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Scope and Contents
Contents
Acquisition of a lipid-laden phenotype by immune cells has been defined in infectious diseases and atherosclerosis but remains largely uncharacterized in cancer. Here, in breast cancer models, we found that neutrophils are induced to accumulate neutral lipids upon interaction with resident mesenchymal cells in the premetastatic lung. Lung mesenchym...
Alternative Titles
Full title
Lung mesenchymal cells elicit lipid storage in neutrophils that fuel breast cancer lung metastasis
Authors, Artists and Contributors
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Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7584447
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7584447
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/s41590-020-0783-5
