Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in li...
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life
About this item
Full title
Author / Creator
Uhlmann, Ruth E. , Rother, Christine , Rasmussen, Jay , Schelle, Juliane , Bergmann, Carina , Ullrich Gavilanes, Emily M. , Fritschi, Sarah K. , Buehler, Anika , Baumann, Frank , Skodras, Angelos , Al-Shaana, Rawaa , Beschorner, Natalie , Ye, Lan , Kaeser, Stephan A. , Obermüller, Ulrike , Christensen, Søren , Kartberg, Fredrik , Stavenhagen, Jeffrey B. , Rahfeld, Jens-Ulrich , Cynis, Holger , Qian, Fang , Weinreb, Paul H. , Bussiere, Thierry , Walker, Lary C. , Staufenbiel, Matthias and Jucker, Mathias
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Amyloid-β (Aβ) deposits are a relatively late consequence of Aβ aggregation in Alzheimer‘s disease. When pathogenic Aβ seeds begin to form, propagate and spread is not known, nor are they biochemically defined. We tested various antibodies for their ability to neutralize Aβ seeds before Aβ deposition becomes detectable in Aβ precursor protein-trans...
Alternative Titles
Full title
Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life
Authors, Artists and Contributors
Author / Creator
Rother, Christine
Rasmussen, Jay
Schelle, Juliane
Bergmann, Carina
Ullrich Gavilanes, Emily M.
Fritschi, Sarah K.
Buehler, Anika
Baumann, Frank
Skodras, Angelos
Al-Shaana, Rawaa
Beschorner, Natalie
Ye, Lan
Kaeser, Stephan A.
Obermüller, Ulrike
Christensen, Søren
Kartberg, Fredrik
Stavenhagen, Jeffrey B.
Rahfeld, Jens-Ulrich
Cynis, Holger
Qian, Fang
Weinreb, Paul H.
Bussiere, Thierry
Walker, Lary C.
Staufenbiel, Matthias
Jucker, Mathias
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7783656
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7783656
Other Identifiers
ISSN
1097-6256
E-ISSN
1546-1726
DOI
10.1038/s41593-020-00737-w
