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34 results for Cynis,+Holger

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Endogenous Retroviruses in Nervous System Disorders
Author / Creator:Gröger, Victoria ; Emmer, Alexander ; Staege, Martin ; Cynis, Holger
Publisher:Switzerland: MDPI AG
Journal title:Pharmaceuticals (Basel, Switzerland), 2021-01, Vol.14 (1), p.70
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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice
Author / Creator:Barendrecht, Susan ; Schreurs, An ; Geissler, Stefanie ; Sabanov, Victor ; Ilse, Victoria ; Rieckmann, Vera ; Eichentopf, Rico ; Künemund, Anja ; Hietel, Benjamin ; Wussow, Sebastian ; Hoffmann, Katrin ; Körber-Ferl, Kerstin ; Pandey, Ravi ; Carter, Gregory W. ; Demuth, Hans-Ulrich ; Holzer, Max ; Roßner, Steffen ; Schilling, Stephan ; Preuss, Christoph ; Balschun, Detlef ; Cynis, Holger
Publisher:England: BioMed Central Ltd
Journal title:Alzheimer's research & therapy, 2023-01, Vol.15 (1), p.16-23, Article 16
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Focal Cerebral Ischemia Induces Expression of Glutaminyl Cyclase along with Downstream Molecular and Cellular Inflammatory Responses
Author / Creator:Höfling, Corinna ; Ulrich, Luise ; Burghardt, Sina ; Donkersloot, Philippa ; Opitz, Michael ; Geissler, Stefanie ; Schilling, Stephan ; Cynis, Holger ; Michalski, Dominik ; Roßner, Steffen
Publisher:Switzerland: MDPI AG
Journal title:Cells (Basel, Switzerland), 2024-08, Vol.13 (17), p.1412
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Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology
Author / Creator:Gnoth, Kathrin ; Piechotta, Anke ; Kleinschmidt, Martin ; Konrath, Sandra ; Schenk, Mathias ; Taudte, Nadine ; Ramsbeck, Daniel ; Rieckmann, Vera ; Geissler, Stefanie ; Eichentopf, Rico ; Barendrecht, Susan ; Hartlage-Rübsamen, Maike ; Demuth, Hans-Ulrich ; Roßner, Steffen ; Cynis, Holger ; Rahfeld, Jens-Ulrich ; Schilling, Stephan
Publisher:England: BioMed Central
Journal title:Alzheimer's research & therapy, 2020-11, Vol.12 (1), p.149-149, Article 149
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Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice
Author / Creator:Gnoth, Kathrin ; Geissler, Stefanie ; Feldhaus, Julia ; Taudte, Nadine ; Ilse, Victoria ; Zürner, Sebastian ; Greiser, Sebastian ; Braumann, Ulf-Dietrich ; Rahfeld, Jens-Ulrich ; Cynis, Holger ; Schilling, Stephan
Publisher:Switzerland: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2022-03, Vol.12 (3), p.399
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Consequences of Amyloid‐β Deficiency for the Liver
Author / Creator:Buniatian, Gayane Hrachia ; Schwinghammer, Ute ; Tremmel, Roman ; Cynis, Holger ; Weiss, Thomas S. ; Weiskirchen, Ralf ; Lauschke, Volker M. ; Youhanna, Sonia ; Ramos, Isbaal ; Valcarcel, Maria ; Seferyan, Torgom ; Rahfeld, Jens‐Ulrich ; Rieckmann, Vera ; Klein, Kathrin ; Buadze, Marine ; Weber, Victoria ; Kolak, Valentina ; Gebhardt, Rolf ; Friedman, Scott L. ; Müller, Ulrike C. ; Schwab, Matthias ; Danielyan, Lusine
Publisher:Germany: John Wiley & Sons, Inc
Journal title:Advanced science, 2024-05, Vol.11 (18), p.e2307734-n/a
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Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver
Author / Creator:Buniatian, Gayane Hrachia ; Weiskirchen, Ralf ; Weiss, Thomas S. ; Schwinghammer, Ute ; Fritz, Martin ; Seferyan, Torgom ; Proksch, Barbara ; Glaser, Michael ; Lourhmati, Ali ; Buadze, Marine ; Borkham-Kamphorst, Erawan ; Gaunitz, Frank ; Gleiter, Christoph H. ; Lang, Thomas ; Schaeffeler, Elke ; Tremmel, Roman ; Cynis, Holger ; Frey, William H. ; Gebhardt, Rolf ; Friedman, Scott L. ; Mikulits, Wolfgang ; Schwab, Matthias ; Danielyan, Lusine
Publisher:Switzerland: MDPI
Journal title:Cells (Basel, Switzerland), 2020-02, Vol.9 (2), p.452
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A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues
Publisher:Vienna: Springer Nature B.V
Journal title:Amino acids, 2013-04, Vol.44 (4), p.1205-1214
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Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β
Author / Creator:Nussbaum, Justin M. ; Schilling, Stephan ; Cynis, Holger ; Silva, Antonia ; Swanson, Eric ; Wangsanut, Tanaporn ; Tayler, Kaycie ; Wiltgen, Brian ; Hatami, Asa ; Rönicke, Raik ; Reymann, Klaus ; Hutter-Paier, Birgit ; Alexandru, Anca ; Jagla, Wolfgang ; Graubner, Sigrid ; Glabe, Charles G. ; Demuth, Hans-Ulrich ; Bloom, George S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-05, Vol.485 (7400), p.651-655
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Immunogenicity of the Envelope Surface Unit of Human Endogenous Retrovirus K18 in Mice
Author / Creator:Ilse, Victoria ; Scholz, Rebekka ; Wermann, Michael ; Naumann, Marcel ; Staege, Martin S. ; Roßner, Steffen ; Cynis, Holger
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2022-08, Vol.23 (15), p.8330
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Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model
Author / Creator:Wirths, Oliver ; Breyhan, Henning ; Cynis, Holger ; Schilling, Stephan ; Demuth, Hans-Ulrich ; Bayer, Thomas A.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Acta neuropathologica, 2009-10, Vol.118 (4), p.487-496
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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life
Author / Creator:Uhlmann, Ruth E. ; Rother, Christine ; Rasmussen, Jay ; Schelle, Juliane ; Bergmann, Carina ; Ullrich Gavilanes, Emily M. ; Fritschi, Sarah K. ; Buehler, Anika ; Baumann, Frank ; Skodras, Angelos ; Al-Shaana, Rawaa ; Beschorner, Natalie ; Ye, Lan ; Kaeser, Stephan A. ; Obermüller, Ulrike ; Christensen, Søren ; Kartberg, Fredrik ; Stavenhagen, Jeffrey B. ; Rahfeld, Jens-Ulrich ; Cynis, Holger ; Qian, Fang ; Weinreb, Paul H. ; Bussiere, Thierry ; Walker, Lary C. ; Staufenbiel, Matthias ; Jucker, Mathias
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2020-12, Vol.23 (12), p.1580-1588
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3D-printed microstructured alginate scaffolds for neural tissue engineering
Author / Creator:Li, Jianfeng ; Hietel, Benjamin ; Brunk, Michael G.K ; Reimers, Armin ; Willems, Christian ; Groth, Thomas ; Cynis, Holger ; Adelung, Rainer ; Schütt, Fabian ; Sacher, Wesley D ; Poon, Joyce K.S
Publisher:England: Elsevier Ltd
Journal title:Trends in biotechnology (Regular ed.), 2025-02, Vol.43 (2), p.447-461
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Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges
Author / Creator:Cynis, Holger ; Frost, Jeffrey L. ; Crehan, Helen ; Lemere, Cynthia A.
Publisher:England: BioMed Central Ltd
Journal title:Molecular neurodegeneration, 2016-06, Vol.11 (1), p.48-48, Article 48
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Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells
Author / Creator:Barth, Marie ; Gröger, Victoria ; Cynis, Holger ; Staege, Martin Sebastian
Publisher:Dordrecht: Springer Netherlands
Journal title:Molecular biology reports, 2019-04, Vol.46 (2), p.1885-1893
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Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology
Author / Creator:Schilling, Stephan ; Zeitschel, Ulrike ; Hoffmann, Torsten ; Heiser, Ulrich ; Francke, Mike ; Kehlen, Astrid ; Holzer, Max ; Hutter-Paier, Birgit ; Prokesch, Manuela ; Windisch, Manfred ; Jagla, Wolfgang ; Schlenzig, Dagmar ; Lindner, Christiane ; Rudolph, Thomas ; Reuter, Gunter ; Cynis, Holger ; Montag, Dirk ; Demuth, Hans-Ulrich ; Rossner, Steffen
Publisher:London: Nature Publishing Group UK
Journal title:Nature medicine, 2008-10, Vol.14 (10), p.1106-1111
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Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions
Author / Creator:Jansig, Edith ; Geissler, Stefanie ; Rieckmann, Vera ; Kuenemund, Anja ; Hietel, Benjamin ; Schenk, Mathias ; Wussow, Sebastian ; Kreideweiss, Patrick ; Panzner, Steffen ; Reinsch, Christian ; Cynis, Holger
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-09, Vol.10 (1), p.15090-15090, Article 15090
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Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level
Author / Creator:Gröger, Victoria ; Wieland, Lisa ; Naumann, Marcel ; Meinecke, Ann-Christin ; Meinhardt, Beate ; Rossner, Steffen ; Ihling, Christian ; Emmer, Alexander ; Staege, Martin S. ; Cynis, Holger
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-10, Vol.21 (21), p.7855
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Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease
Author / Creator:Hartlage-Rübsamen, Maike ; Waniek, Alexander ; Meißner, Juliane ; Morawski, Markus ; Schilling, Stephan ; Jäger, Carsten ; Kleinschmidt, Martin ; Cynis, Holger ; Kehlen, Astrid ; Arendt, Thomas ; Demuth, Hans-Ulrich ; Roßner, Steffen
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2015-04, Vol.129 (4), p.565-583
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Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms
Author / Creator:Hartlage-Rübsamen, Maike ; Morawski, Markus ; Waniek, Alexander ; Jäger, Carsten ; Zeitschel, Ulrike ; Koch, Birgit ; Cynis, Holger ; Schilling, Stephan ; Schliebs, Reinhard ; Demuth, Hans-Ulrich ; Roßner, Steffen
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Acta neuropathologica, 2011-06, Vol.121 (6), p.705-719
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Showing 1 to 20 of 34 results

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Endogenous Retroviruses in Nervous System Disorders

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A novel human tau knock-in mouse model reveals interaction of Abeta and human tau under progressing cerebral amyloidosis in 5xFAD mice

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Focal Cerebral Ischemia Induces Expression of Glutaminyl Cyclase along with Downstream Molecular and Cellular Inflammatory Responses

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Targeting isoaspartate-modified Aβ rescues behavioral deficits in transgenic mice with Alzheimer’s disease-like pathology

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Evidence for Enhanced Efficacy of Passive Immunotherapy against Beta-Amyloid in CD33-Negative 5xFAD Mice

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Consequences of Amyloid‐β Deficiency for the Liver

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Antifibrotic Effects of Amyloid-Beta and Its Loss in Cirrhotic Liver

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A quantitative analysis of spontaneous isoaspartate formation from N-terminal asparaginyl and aspartyl residues

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Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

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Immunogenicity of the Envelope Surface Unit of Human Endogenous Retrovirus K18 in Mice

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Intraneuronal pyroglutamate-Abeta 3–42 triggers neurodegeneration and lethal neurological deficits in a transgenic mouse model

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Acute targeting of pre-amyloid seeds in transgenic mice reduces Alzheimer-like pathology later in life

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3D-printed microstructured alginate scaffolds for neural tissue engineering

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Immunotherapy targeting pyroglutamate-3 Aβ: prospects and challenges

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Identification of human endogenous retrovirus transcripts in Hodgkin Lymphoma cells

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Glutaminyl cyclase inhibition attenuates pyroglutamate Aβ and Alzheimer's disease–like pathology

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Viromers as carriers for mRNA-mediated expression of therapeutic molecules under inflammatory conditions

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Formation of HERV-K and HERV-Fc1 Envelope Family Members is Suppressed on Transcriptional and Translational Level

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Isoglutaminyl cyclase contributes to CCL2-driven neuroinflammation in Alzheimer’s disease

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Glutaminyl cyclase contributes to the formation of focal and diffuse pyroglutamate (pGlu)-Aβ deposits in hippocampus via distinct cellular mechanisms

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