Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-...
Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes
About this item
Full title
Author / Creator
Affandi, Alsya J. , Grabowska, Joanna , Olesek, Katarzyna , Venegas, Miguel Lopez , Barbaria, Arnaud , Rodríguez, Ernesto , Mulder, Patrick P. G. , Pijffers, Helen J. , Ambrosini, Martino , Kalay, Hakan , O’Toole, Tom , Zwart, Eline S. , Kazemier, Geert , Nazmi, Kamran , Bikker, Floris J. , Stöckl, Johannes , van den Eertwegh, Alfons J. M. , de Gruijl, Tanja D. , Storm, Gert , van Kooyk, Yvette and den Haan, Joke M. M.
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Priming of CD8⁺ T cells by dendritic cells (DCs) is crucial for the generation of effective antitumor immune responses. Here, we describe a liposomal vaccine carrier that delivers tumor antigens to human CD169/Siglec-1⁺ antigen-presenting cells using gangliosides as targeting ligands. Ganglioside-liposomes specifically bound to CD169 and were inter...
Alternative Titles
Full title
Selective tumor antigen vaccine delivery to human CD169+ antigen-presenting cells using ganglioside-liposomes
Authors, Artists and Contributors
Author / Creator
Grabowska, Joanna
Olesek, Katarzyna
Venegas, Miguel Lopez
Barbaria, Arnaud
Rodríguez, Ernesto
Mulder, Patrick P. G.
Pijffers, Helen J.
Ambrosini, Martino
Kalay, Hakan
O’Toole, Tom
Zwart, Eline S.
Kazemier, Geert
Nazmi, Kamran
Bikker, Floris J.
Stöckl, Johannes
van den Eertwegh, Alfons J. M.
de Gruijl, Tanja D.
Storm, Gert
van Kooyk, Yvette
den Haan, Joke M. M.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7959579
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_7959579
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2006186117
