Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid...
Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial
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Full title
Author / Creator
Cortes, Jorge, Prof , Perl, Alexander E, MD , Döhner, Hartmut, Prof , Kantarjian, Hagop, Prof , Martinelli, Giovanni, Prof , Kovacsovics, Tibor, Prof , Rousselot, Philippe, Prof , Steffen, Björn, MD , Dombret, Hervé, Prof , Estey, Elihu, Prof , Strickland, Stephen, MD , Altman, Jessica K, MD , Baldus, Claudia D, Prof , Burnett, Alan, Prof , Krämer, Alwin, Prof , Russell, Nigel, Prof , Shah, Neil P, Prof , Smith, Catherine C, MD , Wang, Eunice S, Prof , Ifrah, Norbert, Prof , Gammon, Guy, MRCP , Trone, Denise, MS , Lazzaretto, Deborah, MS and Levis, Mark, Prof
Publisher
England: Elsevier Ltd
Journal title
Language
English
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Publication information
Publisher
England: Elsevier Ltd
Subjects
More information
Scope and Contents
Contents
SummaryBackgroundOld age and FMS-like tyrosine kinase 3 internal tandem duplication ( FLT3-ITD) mutations in patients with acute myeloid leukaemia are associated with early relapse and poor survival. Quizartinib is an oral, highly potent, and selective next-generation FLT3 inhibitor with clinical antileukaemic activity in relapsed or refractory acu...
Alternative Titles
Full title
Quizartinib, an FLT3 inhibitor, as monotherapy in patients with relapsed or refractory acute myeloid leukaemia: an open-label, multicentre, single-arm, phase 2 trial
Authors, Artists and Contributors
Author / Creator
Perl, Alexander E, MD
Döhner, Hartmut, Prof
Kantarjian, Hagop, Prof
Martinelli, Giovanni, Prof
Kovacsovics, Tibor, Prof
Rousselot, Philippe, Prof
Steffen, Björn, MD
Dombret, Hervé, Prof
Estey, Elihu, Prof
Strickland, Stephen, MD
Altman, Jessica K, MD
Baldus, Claudia D, Prof
Burnett, Alan, Prof
Krämer, Alwin, Prof
Russell, Nigel, Prof
Shah, Neil P, Prof
Smith, Catherine C, MD
Wang, Eunice S, Prof
Ifrah, Norbert, Prof
Gammon, Guy, MRCP
Trone, Denise, MS
Lazzaretto, Deborah, MS
Levis, Mark, Prof
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8152787
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8152787
Other Identifiers
ISSN
1470-2045
E-ISSN
1474-5488
DOI
10.1016/S1470-2045(18)30240-7
