Retinoic acid signaling is critical during the totipotency window in early mammalian development
Retinoic acid signaling is critical during the totipotency window in early mammalian development
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New York: Nature Publishing Group US
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Language
English
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New York: Nature Publishing Group US
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Totipotent cells hold enormous potential for regenerative medicine. Thus, the development of cellular models recapitulating totipotent-like features is of paramount importance. Cells resembling the totipotent cells of early embryos arise spontaneously in mouse embryonic stem (ES) cell cultures. Such ‘2-cell-like-cells’ (2CLCs) recapitulate 2-cell-s...
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Retinoic acid signaling is critical during the totipotency window in early mammalian development
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TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8195742
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https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8195742
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ISSN
1545-9993,1545-9985
E-ISSN
1545-9985
DOI
10.1038/s41594-021-00590-w
