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The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8203465

Publication information

Publisher

United States: American Society for Clinical Investigation

More information

Scope and Contents

Contents

Cutaneous melanoma remains the most lethal skin cancer, and ranks third among all malignancies in terms of years of life lost. Despite the advent of immune checkpoint and targeted therapies, only roughly half of patients with advanced melanoma achieve a durable remission. Sirtuin 5 (SIRT5) is a member of the sirtuin family of protein deacylases tha...

Alternative Titles

Full title

The deacylase SIRT5 supports melanoma viability by influencing chromatin dynamics

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8203465

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8203465

Other Identifiers

ISSN

1558-8238,0021-9738

E-ISSN

1558-8238

DOI

10.1172/JCI138926

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