Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2...
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
About this item
Full title
Author / Creator
Dampalla, Chamandi S. , Zheng, Jian , Perera, Krishani Dinali , Wong, Lok-Yin Roy , Meyerholz, David K. , Nguyen, Harry Nhat , Kashipathy, Maithri M. , Battaile, Kevin P. , Lovell, Scott , Kim, Yunjeong , Perlman, Stanley , Groutas, William C. , Chang, Kyeong-Ok and Argonne National Laboratory (ANL), Argonne, IL (United States)
Publisher
United States: National Academy of Sciences
Journal title
Language
English
Formats
Publication information
Publisher
United States: National Academy of Sciences
Subjects
More information
Scope and Contents
Contents
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to be a serious global public health threat. The 3C-like protease (3CLpro) is a virus protease encoded by SARS-CoV-2, which is essential for virus replication. We have previously reported a series of small-molecule 3CLpro inhibitors effective for inhibiting replication...
Alternative Titles
Full title
Postinfection treatment with a protease inhibitor increases survival of mice with a fatal SARS-CoV-2 infection
Authors, Artists and Contributors
Author / Creator
Zheng, Jian
Perera, Krishani Dinali
Wong, Lok-Yin Roy
Meyerholz, David K.
Nguyen, Harry Nhat
Kashipathy, Maithri M.
Battaile, Kevin P.
Lovell, Scott
Kim, Yunjeong
Perlman, Stanley
Groutas, William C.
Chang, Kyeong-Ok
Argonne National Laboratory (ANL), Argonne, IL (United States)
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8307543
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8307543
Other Identifiers
ISSN
0027-8424
E-ISSN
1091-6490
DOI
10.1073/pnas.2101555118
