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Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604728

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

About this item

Full title

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Publisher

New York: Nature Publishing Group US

Journal title

Nature chemical biology, 2021-12, Vol.17 (12), p.1238-1244

Language

English

Formats

Publication information

Publisher

New York: Nature Publishing Group US

More information

Scope and Contents

Contents

Cholecystokinin A receptor (CCK
A
R) belongs to family A G-protein-coupled receptors and regulates nutrient homeostasis upon stimulation by cholecystokinin (CCK). It is an attractive drug target for gastrointestinal and metabolic diseases. One distinguishing feature of CCK
A
R is its ability to interact with a sulfated ligand and to cou...

Alternative Titles

Full title

Ligand recognition and G-protein coupling selectivity of cholecystokinin A receptor

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604728

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8604728

Other Identifiers

ISSN

1552-4450

E-ISSN

1552-4469

DOI

10.1038/s41589-021-00841-3

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