Somatic mutation rates scale with lifespan across mammals
Somatic mutation rates scale with lifespan across mammals
About this item
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Author / Creator
Cagan, Alex , Baez-Ortega, Adrian , Brzozowska, Natalia , Abascal, Federico , Coorens, Tim H. H. , Sanders, Mathijs A. , Lawson, Andrew R. J. , Harvey, Luke M. R. , Bhosle, Shriram , Jones, David , Alcantara, Raul E. , Butler, Timothy M. , Hooks, Yvette , Roberts, Kirsty , Anderson, Elizabeth , Lunn, Sharna , Flach, Edmund , Spiro, Simon , Januszczak, Inez , Wrigglesworth, Ethan , Jenkins, Hannah , Dallas, Tilly , Masters, Nic , Perkins, Matthew W. , Deaville, Robert , Druce, Megan , Bogeska, Ruzhica , Milsom, Michael D. , Neumann, Björn , Gorman, Frank , Constantino-Casas, Fernando , Peachey, Laura , Bochynska, Diana , Smith, Ewan St. John , Gerstung, Moritz , Campbell, Peter J. , Murchison, Elizabeth P. , Stratton, Michael R. and Martincorena, Iñigo
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
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Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
The rates and patterns of somatic mutation in normal tissues are largely unknown outside of humans
1
–
7
. Comparative analyses can shed light on the diversity of mutagenesis across species, and on long-standing hypotheses about the evolution of somatic mutation rates and their role in cancer and ageing. Here we performed whole-genome s...
Alternative Titles
Full title
Somatic mutation rates scale with lifespan across mammals
Authors, Artists and Contributors
Author / Creator
Baez-Ortega, Adrian
Brzozowska, Natalia
Abascal, Federico
Coorens, Tim H. H.
Sanders, Mathijs A.
Lawson, Andrew R. J.
Harvey, Luke M. R.
Bhosle, Shriram
Jones, David
Alcantara, Raul E.
Butler, Timothy M.
Hooks, Yvette
Roberts, Kirsty
Anderson, Elizabeth
Lunn, Sharna
Flach, Edmund
Spiro, Simon
Januszczak, Inez
Wrigglesworth, Ethan
Jenkins, Hannah
Dallas, Tilly
Masters, Nic
Perkins, Matthew W.
Deaville, Robert
Druce, Megan
Bogeska, Ruzhica
Milsom, Michael D.
Neumann, Björn
Gorman, Frank
Constantino-Casas, Fernando
Peachey, Laura
Bochynska, Diana
Smith, Ewan St. John
Gerstung, Moritz
Campbell, Peter J.
Murchison, Elizabeth P.
Stratton, Michael R.
Martincorena, Iñigo
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9021023
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9021023
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-022-04618-z
