Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes
About this item
Full title
Author / Creator
Keinan, Omer , Valentine, Joseph M. , Xiao, Haopeng , Mahata, Sushil K. , Reilly, Shannon M. , Abu-Odeh, Mohammad , Deluca, Julia H. , Dadpey, Benyamin , Cho, Leslie , Pan, Austin , Yu, Ruth T. , Dai, Yang , Liddle, Christopher , Downes, Michael , Evans, Ronald M. , Lusis, Aldons J. , Laakso, Markku , Chouchani, Edward T. , Rydén, Mikael and Saltiel, Alan R.
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
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More information
Scope and Contents
Contents
Adipocytes increase energy expenditure in response to prolonged sympathetic activation via persistent expression of uncoupling protein 1 (UCP1)
1
,
2
. Here we report that the regulation of glycogen metabolism by catecholamines is critical for UCP1 expression. Chronic β-adrenergic activation leads to increased glycogen accumulation in a...
Alternative Titles
Full title
Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes
Authors, Artists and Contributors
Author / Creator
Valentine, Joseph M.
Xiao, Haopeng
Mahata, Sushil K.
Reilly, Shannon M.
Abu-Odeh, Mohammad
Deluca, Julia H.
Dadpey, Benyamin
Cho, Leslie
Pan, Austin
Yu, Ruth T.
Dai, Yang
Liddle, Christopher
Downes, Michael
Evans, Ronald M.
Lusis, Aldons J.
Laakso, Markku
Chouchani, Edward T.
Rydén, Mikael
Saltiel, Alan R.
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9186421
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9186421
Other Identifiers
ISSN
0028-0836
E-ISSN
1476-4687
DOI
10.1038/s41586-021-04019-8
