Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
About this item
Full title
Author / Creator
Dong, Pengfei , Hoffman, Gabriel E. , Apontes, Pasha , Bendl, Jaroslav , Rahman, Samir , Fernando, Michael B. , Zeng, Biao , Vicari, James M. , Zhang, Wen , Girdhar, Kiran , Townsley, Kayla G. , Misir, Ruth , Brennand, Kristen J. , Haroutunian, Vahram , Voloudakis, Georgios , Fullard, John F. , Roussos, Panos , CommonMind Consortium and the CommonMind Consortium
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Identification of risk variants for neuropsychiatric diseases within enhancers underscores the importance of understanding population-level variation in enhancer function in the human brain. Besides regulating tissue-specific and cell-type-specific transcription of target genes, enhancers themselves can be transcribed. By jointly analyzing large-sc...
Alternative Titles
Full title
Population-level variation in enhancer expression identifies disease mechanisms in the human brain
Authors, Artists and Contributors
Author / Creator
Hoffman, Gabriel E.
Apontes, Pasha
Bendl, Jaroslav
Rahman, Samir
Fernando, Michael B.
Zeng, Biao
Vicari, James M.
Zhang, Wen
Girdhar, Kiran
Townsley, Kayla G.
Misir, Ruth
Brennand, Kristen J.
Haroutunian, Vahram
Voloudakis, Georgios
Fullard, John F.
Roussos, Panos
CommonMind Consortium
the CommonMind Consortium
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9547946
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9547946
Other Identifiers
ISSN
1061-4036,1546-1718
E-ISSN
1546-1718
DOI
10.1038/s41588-022-01170-4
