Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelo...
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
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Full title
Author / Creator
Bernard, Elsa , Nannya, Yasuhito , Hasserjian, Robert P. , Devlin, Sean M. , Tuechler, Heinz , Medina-Martinez, Juan S. , Yoshizato, Tetsuichi , Shiozawa, Yusuke , Saiki, Ryunosuke , Malcovati, Luca , Levine, Max F. , Arango, Juan E. , Zhou, Yangyu , Solé, Francesc , Cargo, Catherine A. , Haase, Detlef , Creignou, Maria , Germing, Ulrich , Zhang, Yanming , Gundem, Gunes , Sarian, Araxe , van de Loosdrecht, Arjan A. , Jädersten, Martin , Tobiasson, Magnus , Kosmider, Olivier , Follo, Matilde Y. , Thol, Felicitas , Pinheiro, Ronald F. , Santini, Valeria , Kotsianidis, Ioannis , Boultwood, Jacqueline , Santos, Fabio P. S. , Schanz, Julie , Kasahara, Senji , Ishikawa, Takayuki , Tsurumi, Hisashi , Takaori-Kondo, Akifumi , Kiguchi, Toru , Polprasert, Chantana , Bennett, John M. , Klimek, Virginia M. , Savona, Michael R. , Belickova, Monika , Ganster, Christina , Palomo, Laura , Sanz, Guillermo , Ades, Lionel , Della Porta, Matteo Giovanni , Elias, Harold K. , Smith, Alexandra G. , Werner, Yesenia , Patel, Minal , Viale, Agnès , Vanness, Katelynd , Neuberg, Donna S. , Stevenson, Kristen E. , Menghrajani, Kamal , Bolton, Kelly L. , Fenaux, Pierre , Pellagatti, Andrea , Platzbecker, Uwe , Heuser, Michael , Valent, Peter , Chiba, Shigeru , Miyazaki, Yasushi , Finelli, Carlo , Voso, Maria Teresa , Shih, Lee-Yung , Fontenay, Michaela , Jansen, Joop H. , Cervera, José , Atsuta, Yoshiko , Gattermann, Norbert , Ebert, Benjamin L. , Bejar, Rafael , Greenberg, Peter L. , Cazzola, Mario , Hellström-Lindberg, Eva , Ogawa, Seishi and Papaemmanuil, Elli
Publisher
New York: Nature Publishing Group US
Journal title
Language
English
Formats
Publication information
Publisher
New York: Nature Publishing Group US
Subjects
More information
Scope and Contents
Contents
Tumor protein p53 (
TP53
) is the most frequently mutated gene in cancer
1
,
2
. In patients with myelodysplastic syndromes (MDS),
TP53
mutations are associated with high-risk disease
3
,
4
, rapid transformation to acute myeloid leukemia (AML)
5
, resistance to conventional therapies
6
–
8
and...
Alternative Titles
Full title
Implications of TP53 allelic state for genome stability, clinical presentation and outcomes in myelodysplastic syndromes
Authors, Artists and Contributors
Author / Creator
Nannya, Yasuhito
Hasserjian, Robert P.
Devlin, Sean M.
Tuechler, Heinz
Medina-Martinez, Juan S.
Yoshizato, Tetsuichi
Shiozawa, Yusuke
Saiki, Ryunosuke
Malcovati, Luca
Levine, Max F.
Arango, Juan E.
Zhou, Yangyu
Solé, Francesc
Cargo, Catherine A.
Haase, Detlef
Creignou, Maria
Germing, Ulrich
Zhang, Yanming
Gundem, Gunes
Sarian, Araxe
van de Loosdrecht, Arjan A.
Jädersten, Martin
Tobiasson, Magnus
Kosmider, Olivier
Follo, Matilde Y.
Thol, Felicitas
Pinheiro, Ronald F.
Santini, Valeria
Kotsianidis, Ioannis
Boultwood, Jacqueline
Santos, Fabio P. S.
Schanz, Julie
Kasahara, Senji
Ishikawa, Takayuki
Tsurumi, Hisashi
Takaori-Kondo, Akifumi
Kiguchi, Toru
Polprasert, Chantana
Bennett, John M.
Klimek, Virginia M.
Savona, Michael R.
Belickova, Monika
Ganster, Christina
Palomo, Laura
Sanz, Guillermo
Ades, Lionel
Della Porta, Matteo Giovanni
Elias, Harold K.
Smith, Alexandra G.
Werner, Yesenia
Patel, Minal
Viale, Agnès
Vanness, Katelynd
Neuberg, Donna S.
Stevenson, Kristen E.
Menghrajani, Kamal
Bolton, Kelly L.
Fenaux, Pierre
Pellagatti, Andrea
Platzbecker, Uwe
Heuser, Michael
Valent, Peter
Chiba, Shigeru
Miyazaki, Yasushi
Finelli, Carlo
Voso, Maria Teresa
Shih, Lee-Yung
Fontenay, Michaela
Jansen, Joop H.
Cervera, José
Atsuta, Yoshiko
Gattermann, Norbert
Ebert, Benjamin L.
Bejar, Rafael
Greenberg, Peter L.
Cazzola, Mario
Hellström-Lindberg, Eva
Ogawa, Seishi
Papaemmanuil, Elli
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_469234
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_469234
Other Identifiers
ISSN
1078-8956,1546-170X
E-ISSN
1546-170X
DOI
10.1038/s41591-020-1008-z
