Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug phar...
Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics
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Publisher
New York: Nature Publishing Group US
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Language
English
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Publisher
New York: Nature Publishing Group US
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Contents
Purpose
Variability in pharmacokinetics and drug response is shaped by single-nucleotide variants (SNVs) as well as copy-number variants (CNVs) in genes with importance for drug absorption, distribution, metabolism, and excretion (ADME). While SNVs have been extensively studied, a systematic assessment of the CNV landscape in ADME genes is lacki...
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Novel copy-number variations in pharmacogenes contribute to interindividual differences in drug pharmacokinetics
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TN_cdi_swepub_primary_oai_swepub_ki_se_491758
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_491758
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ISSN
1098-3600
E-ISSN
1530-0366
DOI
10.1038/gim.2017.156
