Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune dise...
Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease
About this item
Full title
Author / Creator
Pfeifle, René , Rothe, Tobias , Ipseiz, Natacha , Scherer, Hans U , Culemann, Stephan , Harre, Ulrike , Ackermann, Jochen A , Seefried, Martina , Kleyer, Arnd , Uderhardt, Stefan , Haugg, Benjamin , Hueber, Axel J , Daum, Patrick , Heidkamp, Gordon F , Ge, Changrong , Böhm, Sybille , Lux, Anja , Schuh, Wolfgang , Magorivska, Iryna , Nandakumar, Kutty S , Lönnblom, Erik , Becker, Christoph , Dudziak, Diana , Wuhrer, Manfred , Rombouts, Yoann , Koeleman, Carolien A , Toes, René , Winkler, Thomas H , Holmdahl, Rikard , Herrmann, Martin , Blüml, Stephan , Nimmerjahn, Falk , Schett, Georg and Krönke, Gerhard
Publisher
United States
Journal title
Language
English
Formats
Publication information
Publisher
United States
Subjects
More information
Scope and Contents
Contents
The checkpoints and mechanisms that contribute to autoantibody-driven disease are as yet incompletely understood. Here we identified the axis of interleukin 23 (IL-23) and the T
17 subset of helper T cells as a decisive factor that controlled the intrinsic inflammatory activity of autoantibodies and triggered the clinical onset of autoimmune art...
Alternative Titles
Full title
Regulation of autoantibody activity by the IL-23-T H 17 axis determines the onset of autoimmune disease
Authors, Artists and Contributors
Author / Creator
Rothe, Tobias
Ipseiz, Natacha
Scherer, Hans U
Culemann, Stephan
Harre, Ulrike
Ackermann, Jochen A
Seefried, Martina
Kleyer, Arnd
Uderhardt, Stefan
Haugg, Benjamin
Hueber, Axel J
Daum, Patrick
Heidkamp, Gordon F
Ge, Changrong
Böhm, Sybille
Lux, Anja
Schuh, Wolfgang
Magorivska, Iryna
Nandakumar, Kutty S
Lönnblom, Erik
Becker, Christoph
Dudziak, Diana
Wuhrer, Manfred
Rombouts, Yoann
Koeleman, Carolien A
Toes, René
Winkler, Thomas H
Holmdahl, Rikard
Herrmann, Martin
Blüml, Stephan
Nimmerjahn, Falk
Schett, Georg
Krönke, Gerhard
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_swepub_primary_oai_swepub_ki_se_501244
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_501244
Other Identifiers
ISSN
1529-2908
E-ISSN
1529-2916
DOI
10.1038/ni.3579
