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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_537038

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

About this item

Full title

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Author / Creator

Voight, Benjamin F, PhD , Peloso, Gina M, PhD , Orho-Melander, Marju, PhD , Frikke-Schmidt, Ruth, DMSc , Jensen, Majken K, PhD , Hólm, Hilma, MD , Johnson, Toby, PhD , Schunkert, Heribert, Prof , Samani, Nilesh J, Prof , Hopewell, Jemma C, PhD , Thompson, John F, Prof , Li, Mingyao, PhD , Newton-Cheh, Christopher, MD , Musunuru, Kiran, MD , Saleheen, Danish, MBBS , Chen, Li, MSc , Stewart, Alexandre FR, PhD , Schillert, Arne, PhD , Thorsteinsdottir, Unnur, PhD , Thorgeirsson, Gudmundur, MD , Engert, James C, PhD , Morgan, Thomas, MD , Spertus, John, Prof , Stoll, Monika, Prof , Berger, Klaus, Prof , Girelli, Domenico, Prof , Patterson, Christopher C, PhD , Devaney, Joseph, PhD , Burnett, Mary-Susan, PhD , Mooser, Vincent, MD , Ripatti, Samuli, PhD , Sinisalo, Juha, MD , Lokki, Marja-Liisa, PhD , Havulinna, Aki, PhD , de Faire, Ulf, Prof , Gigante, Bruna, MD , Ingelsson, Erik, PhD , Wild, Philipp, MD , de Bakker, Paul I W, Prof , Maitland-van der Zee, Anke-Hilse, PhD , Grobbee, Diederick E, Prof , Kamphuisen, Pieter W, PhD , Deneer, Vera H M, PhD , Elbers, Clara C, PhD , Onland-Moret, N Charlotte, PhD , Hofker, Marten H, Prof , Wijmenga, Cisca, Prof , Verschuren, WM Monique, PhD , Rasheed, Asif , Frossard, Philippe , Demissie, Serkalem, PhD , Willer, Cristen, PhD , Do, Ron, PhD , Ordovas, Jose M, Prof , Abecasis, Gonçalo R, Prof , Boehnke, Michael, Prof , Mohlke, Karen L, PhD , Daly, Mark J, PhD , Guiducci, Candace, BS , Surti, Aarti, BS , Gonzalez, Elena, BS , Purcell, Shaun, PhD , Gabriel, Stacey, PhD , Marrugat, Jaume, PhD , Peden, John, PhD , Diemert, Patrick, MD , Willenborg, Christina, MSc , König, Inke R, PhD , Fischer, Marcus, MD , Ziegler, Andreas, PhD , Buysschaert, Ian, MD , Lambrechts, Diether, PhD , Van de Werf, Frans, Prof , Fox, Keith A, Prof , El Mokhtari, Nour Eddine, MD , Rubin, Diana, MD , Schreiber, Stefan, Prof , Schäfer, Arne, PhD , Danesh, John, Prof , Roberts, Robert, Prof , McPherson, Ruth, Prof , Watkins, Hugh, Prof , Hall, Alistair S, Prof , Rimm, Eric, ScD , Boerwinkle, Eric, PhD , Cupples, L Adrienne, Prof , Reilly, Muredach P, MD , Melander, Olle, Prof , Mannucci, Pier M, Prof , Ardissino, Diego, Prof , Siscovick, David, Prof , Elosua, Roberto, PhD , Stefansson, Kari, MD , O'Donnell, Christopher J, MD , Salomaa, Veikko, Prof , Rader, Daniel J, Prof , Peltonen, Leena, Prof , Schwartz, Stephen M, Prof , Altshuler, David, Prof and Kathiresan, Sekar, Dr MD

Publisher

Kidlington: Elsevier Ltd

Journal title

The Lancet (British edition), 2012-08, Vol.380 (9841), p.572-580

Language

English

Formats

Publication information

Publisher

Kidlington: Elsevier Ltd

More information

Scope and Contents

Contents

Summary Background High plasma HDL cholesterol is associated with reduced risk of myocardial infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are randomly assigned at meiosis, are independent of non-genetic confounding, and are unmodified by disease processes, mendelian randomisation can be used to t...

Alternative Titles

Full title

Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study

Authors, Artists and Contributors

Author / Creator

Voight, Benjamin F, PhD
Peloso, Gina M, PhD
Orho-Melander, Marju, PhD
Frikke-Schmidt, Ruth, DMSc
Jensen, Majken K, PhD
Hólm, Hilma, MD
Johnson, Toby, PhD
Schunkert, Heribert, Prof
Samani, Nilesh J, Prof
Hopewell, Jemma C, PhD
Thompson, John F, Prof
Li, Mingyao, PhD
Newton-Cheh, Christopher, MD
Musunuru, Kiran, MD
Saleheen, Danish, MBBS
Chen, Li, MSc
Stewart, Alexandre FR, PhD
Schillert, Arne, PhD
Thorsteinsdottir, Unnur, PhD
Thorgeirsson, Gudmundur, MD
Engert, James C, PhD
Morgan, Thomas, MD
Spertus, John, Prof
Stoll, Monika, Prof
Berger, Klaus, Prof
Girelli, Domenico, Prof
Patterson, Christopher C, PhD
Devaney, Joseph, PhD
Burnett, Mary-Susan, PhD
Mooser, Vincent, MD
Ripatti, Samuli, PhD
Sinisalo, Juha, MD
Lokki, Marja-Liisa, PhD
Havulinna, Aki, PhD
de Faire, Ulf, Prof
Gigante, Bruna, MD
Ingelsson, Erik, PhD
Wild, Philipp, MD
de Bakker, Paul I W, Prof
Maitland-van der Zee, Anke-Hilse, PhD
Grobbee, Diederick E, Prof
Kamphuisen, Pieter W, PhD
Deneer, Vera H M, PhD
Elbers, Clara C, PhD
Onland-Moret, N Charlotte, PhD
Hofker, Marten H, Prof
Wijmenga, Cisca, Prof
Verschuren, WM Monique, PhD
Rasheed, Asif
Frossard, Philippe
Demissie, Serkalem, PhD
Willer, Cristen, PhD
Do, Ron, PhD
Ordovas, Jose M, Prof
Abecasis, Gonçalo R, Prof
Boehnke, Michael, Prof
Mohlke, Karen L, PhD
Daly, Mark J, PhD
Guiducci, Candace, BS
Surti, Aarti, BS
Gonzalez, Elena, BS
Purcell, Shaun, PhD
Gabriel, Stacey, PhD
Marrugat, Jaume, PhD
Peden, John, PhD
Diemert, Patrick, MD
Willenborg, Christina, MSc
König, Inke R, PhD
Fischer, Marcus, MD
Ziegler, Andreas, PhD
Buysschaert, Ian, MD
Lambrechts, Diether, PhD
Van de Werf, Frans, Prof
Fox, Keith A, Prof
El Mokhtari, Nour Eddine, MD
Rubin, Diana, MD
Schreiber, Stefan, Prof
Schäfer, Arne, PhD
Danesh, John, Prof
Roberts, Robert, Prof
McPherson, Ruth, Prof
Watkins, Hugh, Prof
Hall, Alistair S, Prof
Rimm, Eric, ScD
Boerwinkle, Eric, PhD
Cupples, L Adrienne, Prof
Reilly, Muredach P, MD
Melander, Olle, Prof
Mannucci, Pier M, Prof
Ardissino, Diego, Prof
Siscovick, David, Prof
Elosua, Roberto, PhD
Stefansson, Kari, MD
O'Donnell, Christopher J, MD
Salomaa, Veikko, Prof
Rader, Daniel J, Prof
Peltonen, Leena, Prof
Schwartz, Stephen M, Prof
Altshuler, David, Prof
Kathiresan, Sekar, Dr MD

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_537038

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_537038

Other Identifiers

ISSN

0140-6736,1474-547X

E-ISSN

1474-547X

DOI

10.1016/S0140-6736(12)60312-2