Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects
Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Language
English
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Publisher
Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag
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Contents
Purpose Ultrarapid drug metabolism of antidepressants has been associated with therapeutic failures. The CYP2C19*17 allele has been associated with higher levels of CYP2C19 gene transcription and increased rates of omeprazole and mephenytoin metabolism. The aim of this study was to compare the impact of the CYP2C19*17 allele on omeprazole single-do...
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Full title
Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects
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TN_cdi_swepub_primary_oai_swepub_ki_se_563053
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_563053
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ISSN
0031-6970
E-ISSN
1432-1041
DOI
10.1007/s00228-008-0529-z