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Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_563053

Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

About this item

Full title

Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

Journal title

European journal of clinical pharmacology, 2008-12, Vol.64 (12), p.1175-1179

Language

English

Formats

Publication information

Publisher

Berlin/Heidelberg: Berlin/Heidelberg : Springer-Verlag

More information

Scope and Contents

Contents

Purpose Ultrarapid drug metabolism of antidepressants has been associated with therapeutic failures. The CYP2C19*17 allele has been associated with higher levels of CYP2C19 gene transcription and increased rates of omeprazole and mephenytoin metabolism. The aim of this study was to compare the impact of the CYP2C19*17 allele on omeprazole single-do...

Alternative Titles

Full title

Kinetics of omeprazole and escitalopram in relation to the CYP2C1917 allele in healthy subjects

Identifiers

Primary Identifiers

Record Identifier

TN_cdi_swepub_primary_oai_swepub_ki_se_563053

Permalink

https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_swepub_primary_oai_swepub_ki_se_563053

Other Identifiers

ISSN

0031-6970

E-ISSN

1432-1041

DOI

10.1007/s00228-008-0529-z