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Select record 21
ArticlesPeer ReviewedFull Text
Autophagy in healthy aging and disease
Author / Creator:Aman, Yahyah ; Schmauck-Medina, Tomas ; Hansen, Malene ; Morimoto, Richard I. ; Simon, Anna Katharina ; Bjedov, Ivana ; Palikaras, Konstantinos ; Simonsen, Anne ; Johansen, Terje ; Tavernarakis, Nektarios ; Rubinsztein, David C. ; Partridge, Linda ; Kroemer, Guido ; Labbadia, John ; Fang, Evandro F.
Publisher:New York: Nature Publishing Group US
Journal title:Nature aging, 2021-08, Vol.1 (8), p.634-650
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ArticlesPeer ReviewedFull Text
Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2
Author / Creator:Hu, Yuxia ; Zhang, Zhao ; Mao, Qiyu ; Zhang, Xiang ; Hao, Aihua ; Xun, Yu ; Wang, Yeda ; Han, Lin ; Zhan, Wuqiang ; Liu, Qianying ; Yin, Yue ; Peng, Chao ; Moresco, Eva Marie Y. ; Chen, Zhenguo ; Beutler, Bruce ; Sun, Lei
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2024-02, Vol.31 (2), p.336-350
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ArticlesPeer ReviewedFull Text
Structural insights into the catalysis and regulation of E3 ubiquitin ligases
Author / Creator:Buetow, Lori ; Huang, Danny T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Molecular cell biology, 2016-10, Vol.17 (10), p.626-642
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The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system
Author / Creator:Ji, Chang Hoon ; Kim, Hee Yeon ; Lee, Min Ju ; Heo, Ah Jung ; Park, Daniel Youngjae ; Lim, Sungsu ; Shin, Seulgi ; Ganipisetti, Srinivasrao ; Yang, Woo Seung ; Jung, Chang An ; Kim, Kun Young ; Jeong, Eun Hye ; Park, Sun Ho ; Bin Kim, Su ; Lee, Su Jin ; Na, Jeong Eun ; Kang, Ji In ; Chi, Hyung Min ; Kim, Hyun Tae ; Kim, Yun Kyung ; Kim, Bo Yeon ; Kwon, Yong Tae
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.904-904, Article 904
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ArticlesPeer ReviewedFull Text
Ribosome-associated protein quality control
Author / Creator:Brandman, Onn ; Hegde, Ramanujan S
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2016-01, Vol.23 (1), p.7-15
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Proteasome inhibitors in cancer therapy
Author / Creator:Manasanch, Elisabet E. ; Orlowski, Robert Z.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2017-07, Vol.14 (7), p.417-433
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ArticlesPeer ReviewedFull Text
Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4
Author / Creator:Skrott, Zdenek ; Mistrik, Martin ; Andersen, Klaus Kaae ; Friis, Søren ; Majera, Dusana ; Gursky, Jan ; Ozdian, Tomas ; Bartkova, Jirina ; Turi, Zsofia ; Moudry, Pavel ; Kraus, Marianne ; Michalova, Martina ; Vaclavkova, Jana ; Dzubak, Petr ; Vrobel, Ivo ; Pouckova, Pavla ; Sedlacek, Jindrich ; Miklovicova, Andrea ; Kutt, Anne ; Li, Jing ; Mattova, Jana ; Driessen, Christoph ; Dou, Q. Ping ; Olsen, Jørgen ; Hajduch, Marian ; Cvek, Boris ; Deshaies, Raymond J. ; Bartek, Jiri
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-12, Vol.552 (7684), p.194-199
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ArticlesPeer ReviewedFull Text
Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1
Author / Creator:Breckel, Carolyn Allain ; Johnson, Zane M. ; Hickey, Christopher M. ; Hochstrasser, Mark
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-01, Vol.14 (1), p.2048-16, Article 2048
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ArticlesPeer ReviewedFull Text
SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection
Author / Creator:Gassen, Nils C. ; Niemeyer, Daniela ; Muth, Doreen ; Corman, Victor M. ; Martinelli, Silvia ; Gassen, Alwine ; Hafner, Kathrin ; Papies, Jan ; Mösbauer, Kirstin ; Zellner, Andreas ; Zannas, Anthony S. ; Herrmann, Alexander ; Holsboer, Florian ; Brack-Werner, Ruth ; Boshart, Michael ; Müller-Myhsok, Bertram ; Drosten, Christian ; Müller, Marcel A. ; Rein, Theo
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5770-16, Article 5770
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ArticlesPeer ReviewedFull Text
The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice
Author / Creator:Yesbolatova, Aisha ; Saito, Yuichiro ; Kitamoto, Naomi ; Makino-Itou, Hatsune ; Ajima, Rieko ; Nakano, Risako ; Nakaoka, Hirofumi ; Fukui, Kosuke ; Gamo, Kanae ; Tominari, Yusuke ; Takeuchi, Haruki ; Saga, Yumiko ; Hayashi, Ken-ichiro ; Kanemaki, Masato T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-11, Vol.11 (1), p.5701-5701, Article 5701
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ArticlesPeer ReviewedFull Text
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
Author / Creator:Shapira, Tirosh ; Monreal, I. Abrrey ; Dion, Sébastien P. ; Buchholz, David W. ; Imbiakha, Brian ; Olmstead, Andrea D. ; Jager, Mason ; Désilets, Antoine ; Gao, Guang ; Martins, Mathias ; Vandal, Thierry ; Thompson, Connor A. H. ; Chin, Aaleigha ; Rees, William D. ; Steiner, Theodore ; Nabi, Ivan Robert ; Marsault, Eric ; Sahler, Julie ; Diel, Diego G. ; Van de Walle, Gerlinde R. ; August, Avery ; Whittaker, Gary R. ; Boudreault, Pierre-Luc ; Leduc, Richard ; Aguilar, Hector C. ; Jean, François
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-05, Vol.605 (7909), p.340-348
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Select record 32
ArticlesPeer ReviewedFull Text
Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response
Author / Creator:Olson, Oakley C. ; Joyce, Johanna A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2015-12, Vol.15 (12), p.712-729
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ArticlesPeer ReviewedFull Text
MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control
Author / Creator:König, Tim ; Nolte, Hendrik ; Aaltonen, Mari J. ; Tatsuta, Takashi ; Krols, Michiel ; Stroh, Thomas ; Langer, Thomas ; McBride, Heidi M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2021-12, Vol.23 (12), p.1271-1286
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ArticlesPeer ReviewedFull Text
Neutrophils direct preexisting matrix to initiate repair in damaged tissues
Author / Creator:Fischer, Adrian ; Wannemacher, Juliane ; Christ, Simon ; Koopmans, Tim ; Kadri, Safwen ; Zhao, Jiakuan ; Gouda, Mahesh ; Ye, Haifeng ; Mück-Häusl, Martin ; Krenn, Peter W. ; Machens, Hans-Günther ; Fässler, Reinhard ; Neumann, Philipp-Alexander ; Hauck, Stefanie M. ; Rinkevich, Yuval
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-04, Vol.23 (4), p.518-531
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ArticlesPeer ReviewedFull Text
Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines
Author / Creator:Olivares, Adrian O. ; Baker, Tania A. ; Sauer, Robert T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2016-01, Vol.14 (1), p.33-44
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ArticlesPeer ReviewedFull Text
p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response
Author / Creator:Kageyama, Shun ; Gudmundsson, Sigurdur Runar ; Sou, Yu-Shin ; Ichimura, Yoshinobu ; Tamura, Naoki ; Kazuno, Saiko ; Ueno, Takashi ; Miura, Yoshiki ; Noshiro, Daisuke ; Abe, Manabu ; Mizushima, Tsunehiro ; Miura, Nobuaki ; Okuda, Shujiro ; Motohashi, Hozumi ; Lee, Jin-A ; Sakimura, Kenji ; Ohe, Tomoyuki ; Noda, Nobuo N. ; Waguri, Satoshi ; Eskelinen, Eeva-Liisa ; Komatsu, Masaaki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.16-16, Article 16
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ArticlesPeer ReviewedFull Text
Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system
Author / Creator:Rinaldi, Laura ; Delle Donne, Rossella ; Catalanotti, Bruno ; Torres-Quesada, Omar ; Enzler, Florian ; Moraca, Federica ; Nisticò, Robert ; Chiuso, Francesco ; Piccinin, Sonia ; Bachmann, Verena ; Lindner, Herbert H ; Garbi, Corrado ; Scorziello, Antonella ; Russo, Nicola Antonino ; Synofzik, Matthis ; Stelzl, Ulrich ; Annunziato, Lucio ; Stefan, Eduard ; Feliciello, Antonio
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-06, Vol.10 (1), p.2572-2572, Article 2572
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Select record 38
ArticlesPeer ReviewedFull Text
Mechanism of ubiquitylation by dimeric RING ligase RNF4
Author / Creator:Plechanovová, Anna ; Jaffray, Ellis G ; McMahon, Stephen A ; Johnson, Kenneth A ; Navrátilová, Iva ; Naismith, James H ; Hay, Ronald T
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2011-09, Vol.18 (9), p.1052-1059
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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation
Author / Creator:Liu, Qingjun ; Zhang, Shihui ; Sun, Zhongjie ; Guo, Xiao ; Zhou, Hong
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2019-11, Vol.26 (11), p.2386-2399
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Select record 40
ArticlesPeer ReviewedFull Text
Roles of F-box proteins in cancer
Author / Creator:Wang, Zhiwei ; Liu, Pengda ; Inuzuka, Hiroyuki ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2014-04, Vol.14 (4), p.233-247
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Showing 21 to 40 of 519 results

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Autophagy in healthy aging and disease

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Dynamic molecular architecture and substrate recruitment of cullin3–RING E3 ligase CRL3KBTBD2

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Structural insights into the catalysis and regulation of E3 ubiquitin ligases

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The AUTOTAC chemical biology platform for targeted protein degradation via the autophagy-lysosome system

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Ribosome-associated protein quality control

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Proteasome inhibitors in cancer therapy

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Alcohol-abuse drug disulfiram targets cancer via p97 segregase adaptor NPL4

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Yeast 26S proteasome nuclear import is coupled to nucleus-specific degradation of the karyopherin adaptor protein Sts1

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SKP2 attenuates autophagy through Beclin1-ubiquitination and its inhibition reduces MERS-Coronavirus infection

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The auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice

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A﻿ TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

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Cysteine cathepsin proteases: regulators of cancer progression and therapeutic response

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MIROs and DRP1 drive mitochondrial-derived vesicle biogenesis and promote quality control

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Neutrophils direct preexisting matrix to initiate repair in damaged tissues

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Mechanistic insights into bacterial AAA+ proteases and protein-remodelling machines

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p62/SQSTM1-droplet serves as a platform for autophagosome formation and anti-oxidative stress response

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Feedback inhibition of cAMP effector signaling by a chaperone-assisted ubiquitin system

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Mechanism of ubiquitylation by dimeric RING ligase RNF4

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E3 ubiquitin ligase Nedd4 is a key negative regulator for non-canonical inflammasome activation

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Roles of F-box proteins in cancer

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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic