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Select record 21
ArticlesPeer ReviewedFull Text
L1 drives IFN in senescent cells and promotes age-associated inflammation
Author / Creator:De Cecco, Marco ; Ito, Takahiro ; Petrashen, Anna P. ; Elias, Amy E. ; Skvir, Nicholas J. ; Criscione, Steven W. ; Caligiana, Alberto ; Brocculi, Greta ; Adney, Emily M. ; Boeke, Jef D. ; Le, Oanh ; Beauséjour, Christian ; Ambati, Jayakrishna ; Ambati, Kameshwari ; Simon, Matthew ; Seluanov, Andrei ; Gorbunova, Vera ; Slagboom, P. Eline ; Helfand, Stephen L. ; Neretti, Nicola ; Sedivy, John M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-02, Vol.566 (7742), p.73-78
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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity
Author / Creator:Kinker, Gabriela S. ; Greenwald, Alissa C. ; Tal, Rotem ; Orlova, Zhanna ; Cuoco, Michael S. ; McFarland, James M. ; Warren, Allison ; Rodman, Christopher ; Roth, Jennifer A. ; Bender, Samantha A. ; Kumar, Bhavna ; Rocco, James W. ; Fernandes, Pedro A. C. M. ; Mader, Christopher C. ; Keren-Shaul, Hadas ; Plotnikov, Alexander ; Barr, Haim ; Tsherniak, Aviad ; Rozenblatt-Rosen, Orit ; Krizhanovsky, Valery ; Puram, Sidharth V. ; Regev, Aviv ; Tirosh, Itay
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2020-11, Vol.52 (11), p.1208-1218
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Cytoplasmic chromatin triggers inflammation in senescence and cancer
Author / Creator:Dou, Zhixun ; Ghosh, Kanad ; Vizioli, Maria Grazia ; Zhu, Jiajun ; Sen, Payel ; Wangensteen, Kirk J. ; Simithy, Johayra ; Lan, Yemin ; Lin, Yanping ; Zhou, Zhuo ; Capell, Brian C. ; Xu, Caiyue ; Xu, Mingang ; Kieckhaefer, Julia E. ; Jiang, Tianying ; Shoshkes-Carmel, Michal ; Tanim, K. M. Ahasan Al ; Barber, Glen N. ; Seykora, John T. ; Millar, Sarah E. ; Kaestner, Klaus H. ; Garcia, Benjamin A. ; Adams, Peter D. ; Berger, Shelley L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-10, Vol.550 (7676), p.402-406
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A multidimensional systems biology analysis of cellular senescence in aging and disease
Author / Creator:Avelar, Roberto A ; Ortega, Javier Gómez ; Tacutu, Robi ; Tyler, Eleanor J ; Bennett, Dominic ; Binetti, Paolo ; Budovsky, Arie ; Chatsirisupachai, Kasit ; Johnson, Emily ; Murray, Alex ; Shields, Samuel ; Tejada-Martinez, Daniela ; Thornton, Daniel ; Fraifeld, Vadim E ; Bishop, Cleo L ; de Magalhães, João Pedro
Publisher:England: BioMed Central Ltd
Journal title:Genome Biology, 2020-04, Vol.21 (1), p.91-91, Article 91
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Measuring biological aging in humans: A quest
Author / Creator:Ferrucci, Luigi ; Gonzalez‐Freire, Marta ; Fabbri, Elisa ; Simonsick, Eleanor ; Tanaka, Toshiko ; Moore, Zenobia ; Salimi, Shabnam ; Sierra, Felipe ; Cabo, Rafael
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2020-02, Vol.19 (2), p.e13080-n/a
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Pattern recognition receptors in health and diseases
Author / Creator:Li, Danyang ; Wu, Minghua
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2021-08, Vol.6 (1), p.291-24, Article 291
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Aging and aging-related diseases: from molecular mechanisms to interventions and treatments
Author / Creator:Guo, Jun ; Huang, Xiuqing ; Dou, Lin ; Yan, Mingjing ; Shen, Tao ; Tang, Weiqing ; Li, Jian
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2022-12, Vol.7 (1), p.391-40, Article 391
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Molecular and physiological manifestations and measurement of aging in humans
Author / Creator:Khan, Sadiya S. ; Singer, Benjamin D. ; Vaughan, Douglas E.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2017-08, Vol.16 (4), p.624-633
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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
Author / Creator:Xu, Ming ; Tchkonia, Tamara ; Ding, Husheng ; Ogrodnik, Mikolaj ; Lubbers, Ellen R. ; Pirtskhalava, Tamar ; White, Thomas A. ; Johnson, Kurt O. ; Stout, Michael B. ; Mezera, Vojtech ; Giorgadze, Nino ; Jensen, Michael D. ; LeBrasseur, Nathan K. ; Kirkland, James L.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-11, Vol.112 (46), p.E6301-E6310
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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases
Author / Creator:Watanabe, Sugiko ; Kawamoto, Shimpei ; Ohtani, Naoko ; Hara, Eiji
Publisher:England: John Wiley and Sons Inc
Journal title:Cancer science, 2017-04, Vol.108 (4), p.563-569
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Targeting senescent cells alleviates obesity‐induced metabolic dysfunction
Author / Creator:Palmer, Allyson K. ; Xu, Ming ; Zhu, Yi ; Pirtskhalava, Tamar ; Weivoda, Megan M. ; Hachfeld, Christine M. ; Prata, Larissa G. ; Dijk, Theo H. ; Verkade, Esther ; Casaclang‐Verzosa, Grace ; Johnson, Kurt O. ; Cubro, Hajrunisa ; Doornebal, Ewald J. ; Ogrodnik, Mikolaj ; Jurk, Diana ; Jensen, Michael D. ; Chini, Eduardo N. ; Miller, Jordan D. ; Matveyenko, Aleksey ; Stout, Michael B. ; Schafer, Marissa J. ; White, Thomas A. ; Hickson, LaTonya J. ; Demaria, Marco ; Garovic, Vesna ; Grande, Joseph ; Arriaga, Edgar A. ; Kuipers, Folkert ; Zglinicki, Thomas ; LeBrasseur, Nathan K. ; Campisi, Judith ; Tchkonia, Tamar ; Kirkland, James L.
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-06, Vol.18 (3), p.e12950-n/a
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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk
Author / Creator:Zannas, Anthony S. ; Jia, Meiwen ; Hafner, Kathrin ; Baumert, Jens ; Wiechmann, Tobias ; Pape, Julius C. ; Arloth, Janine ; Ködel, Maik ; Martinelli, Silvia ; Roitman, Maria ; Röh, Simone ; Haehle, Andreas ; Emeny, Rebecca T. ; Iurato, Stella ; Carrillo-Roa, Tania ; Lahti, Jari ; Räikkönen, Katri ; Eriksson, Johan G. ; Drake, Amanda J. ; Waldenberger, Melanie ; Wahl, Simone ; Kunze, Sonja ; Lucae, Susanne ; Bradley, Bekh ; Gieger, Christian ; Hausch, Felix ; Smith, Alicia K. ; Ressler, Kerry J. ; Müller-Myhsok, Bertram ; Ladwig, Karl-Heinz ; Rein, Theo ; Gassen, Nils C. ; Binder, Elisabeth B.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2019-06, Vol.116 (23), p.11370-11379
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Aging increases cell-to-cell transcriptional variability upon immune stimulation
Author / Creator:Martinez-Jimenez, Celia Pilar ; Eling, Nils ; Chen, Hung-Chang ; Vallejos, Catalina A. ; Kolodziejczyk, Aleksandra A. ; Connor, Frances ; Stojic, Lovorka ; Rayner, Timothy F. ; Stubbington, Michael J. T. ; Teichmann, Sarah A. ; de la Roche, Maike ; Marioni, John C. ; Odom, Duncan T.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-03, Vol.355 (6332), p.1433-1436
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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory
Author / Creator:Lanna, Alessio ; Vaz, Bruno ; D’Ambra, Clara ; Valvo, Salvatore ; Vuotto, Claudia ; Chiurchiù, Valerio ; Devine, Oliver ; Sanchez, Massimo ; Borsellino, Giovanna ; Akbar, Arne N. ; De Bardi, Marco ; Gilroy, Derek W. ; Dustin, Michael L. ; Blumer, Brendan ; Karin, Michael
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2022-10, Vol.24 (10), p.1461-1474
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Comparison of telomere length measurement methods
Author / Creator:Lai, Tsung-Po ; Wright, Woodring E. ; Shay, Jerry W.
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series B. Biological sciences, 2018-03, Vol.373 (1741), p.20160451-20160451
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Immunosenescence: molecular mechanisms and diseases
Author / Creator:Liu, Zaoqu ; Liang, Qimeng ; Ren, Yuqing ; Guo, Chunguang ; Ge, Xiaoyong ; Wang, Libo ; Cheng, Quan ; Luo, Peng ; Zhang, Yi ; Han, Xinwei
Publisher:London: Nature Publishing Group UK
Journal title:Signal transduction and targeted therapy, 2023-05, Vol.8 (1), p.200-200, Article 200
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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment
Author / Creator:Jeon, Ok Hee ; Kim, Chaekyu ; Laberge, Remi-Martin ; Demaria, Marco ; Rathod, Sona ; Vasserot, Alain P ; Chung, Jae Wook ; Kim, Do Hun ; Poon, Yan ; David, Nathaniel ; Baker, Darren J ; van Deursen, Jan M ; Campisi, Judith ; Elisseeff, Jennifer H
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-06, Vol.23 (6), p.775-781
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Senescence-associated reprogramming promotes cancer stemness
Author / Creator:Milanovic, Maja ; Fan, Dorothy N. Y. ; Belenki, Dimitri ; Däbritz, J. Henry M. ; Zhao, Zhen ; Yu, Yong ; Dörr, Jan R. ; Dimitrova, Lora ; Lenze, Dido ; Monteiro Barbosa, Ines A. ; Mendoza-Parra, Marco A. ; Kanashova, Tamara ; Metzner, Marlen ; Pardon, Katharina ; Reimann, Maurice ; Trumpp, Andreas ; Dörken, Bernd ; Zuber, Johannes ; Gronemeyer, Hinrich ; Hummel, Michael ; Dittmar, Gunnar ; Lee, Soyoung ; Schmitt, Clemens A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-01, Vol.553 (7686), p.96-100
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Select record 39
ArticlesPeer ReviewedFull Text
Cellular senescence in osteoarthritis pathology
Author / Creator:McCulloch, Kendal ; Litherland, Gary J. ; Rai, Taranjit Singh
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2017-04, Vol.16 (2), p.210-218
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Targeting cellular senescence prevents age-related bone loss in mice
Author / Creator:Farr, Joshua N ; Xu, Ming ; Weivoda, Megan M ; Monroe, David G ; Fraser, Daniel G ; Onken, Jennifer L ; Negley, Brittany A ; Sfeir, Jad G ; Ogrodnik, Mikolaj B ; Hachfeld, Christine M ; LeBrasseur, Nathan K ; Drake, Matthew T ; Pignolo, Robert J ; Pirtskhalava, Tamar ; Tchkonia, Tamara ; Oursler, Merry Jo ; Kirkland, James L ; Khosla, Sundeep
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-09, Vol.23 (9), p.1072-1079
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L1 drives IFN in senescent cells and promotes age-associated inflammation

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Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity

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Cytoplasmic chromatin triggers inflammation in senescence and cancer

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A multidimensional systems biology analysis of cellular senescence in aging and disease

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Measuring biological aging in humans: A quest

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Pattern recognition receptors in health and diseases

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Aging and aging-related diseases: from molecular mechanisms to interventions and treatments

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Molecular and physiological manifestations and measurement of aging in humans

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JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age

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Impact of senescence‐associated secretory phenotype and its potential as a therapeutic target for senescence‐associated diseases

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Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk

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Aging increases cell-to-cell transcriptional variability upon immune stimulation

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An intercellular transfer of telomeres rescues T cells from senescence and promotes long-term immunological memory

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Comparison of telomere length measurement methods

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Immunosenescence: molecular mechanisms and diseases

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Local clearance of senescent cells attenuates the development of post-traumatic osteoarthritis and creates a pro-regenerative environment

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Senescence-associated reprogramming promotes cancer stemness

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Cellular senescence in osteoarthritis pathology

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Targeting cellular senescence prevents age-related bone loss in mice

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