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Select record 21
ArticlesPeer ReviewedFull Text
The CD70-CD27 axis in oncology: the new kids on the block
Author / Creator:Flieswasser, Tal ; Van den Eynde, Astrid ; Van Audenaerde, Jonas ; De Waele, Jorrit ; Lardon, Filip ; Riether, Carsten ; de Haard, Hans ; Smits, Evelien ; Pauwels, Patrick ; Jacobs, Julie
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2022-01, Vol.41 (1), p.12-12, Article 12
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ArticlesPeer ReviewedFull Text
A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels
Author / Creator:Khetarpal, Sumeet A ; Zeng, Xuemei ; Millar, John S ; Vitali, Cecilia ; Somasundara, Amritha Varshini Hanasoge ; Zanoni, Paolo ; Landro, James A ; Barucci, Nicole ; Zavadoski, William J ; Sun, Zhiyuan ; de Haard, Hans ; Toth, Ildikó V ; Peloso, Gina M ; Natarajan, Pradeep ; Cuchel, Marina ; Lund-Katz, Sissel ; Phillips, Michael C ; Tall, Alan R ; Kathiresan, Sekar ; DaSilva-Jardine, Paul ; Yates, Nathan A ; Rader, Daniel J
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2017-09, Vol.23 (9), p.1086-1094
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ArticlesPeer ReviewedFull Text
The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement
Author / Creator:Brinkhaus, Maximilian ; Pannecoucke, Erwin ; van der Kooi, Elvera J. ; Bentlage, Arthur E. H. ; Derksen, Ninotska I. L. ; Andries, Julie ; Balbino, Bianca ; Sips, Magdalena ; Ulrichts, Peter ; Verheesen, Peter ; de Haard, Hans ; Rispens, Theo ; Savvides, Savvas N. ; Vidarsson, Gestur
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-10, Vol.13 (1), p.6073-6073, Article 6073
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ArticlesPeer ReviewedFull Text
Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies
Author / Creator:Roovers, Rob C. ; Laeremans, Toon ; Huang, Lieven ; De Taeye, Severine ; Verkleij, Arie J. ; Revets, Hilde ; de Haard, Hans J. ; van Bergen en Henegouwen, Paul M. P.
Publisher:Heidelberg: Springer Nature B.V
Journal title:Cancer Immunology, Immunotherapy, 2007-03, Vol.56 (3), p.303-317
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ArticlesPeer ReviewedFull Text
Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C
Author / Creator:Strokappe, Nika ; Szynol, Agnieszka ; Aasa-Chapman, Marlèn ; Gorlani, Andrea ; Forsman Quigley, Anna ; Hulsik, David Lutje ; Chen, Lei ; Weiss, Robin ; de Haard, Hans ; Verrips, Theo
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-03, Vol.7 (3), p.e33298
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ArticlesPeer ReviewedFull Text
VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells
Author / Creator:Heukers, Raimond ; Mashayekhi, Vida ; Ramirez-Escudero, Mercedes ; de Haard, Hans ; Verrips, Theo C. ; van Bergen en Henegouwen, Paul. M.P. ; Oliveira, Sabrina
Publisher:Basel: MDPI AG
Journal title:Antibodies (Basel), 2019-06, Vol.8 (2), p.26
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ArticlesPeer ReviewedFull Text
Site-specific 68Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models
Author / Creator:Dewulf, Jonatan ; Flieswasser, Tal ; Delahaye, Tim ; Vangestel, Christel ; Miranda, Alan ; de Haard, Hans ; Jacobs, Julie ; Smits, Evelien ; Van den Wyngaert, Tim ; Elvas, Filipe
Publisher:Cham: Springer International Publishing
Journal title:EJNMMI radiopharmacy and chemistry, 2023-04, Vol.8 (1), p.8-8, Article 8
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ArticlesPeer ReviewedFull Text
Selection of Nanobodies that Target Human Neonatal Fc Receptor
Author / Creator:Andersen, Jan Terje ; Gonzalez-Pajuelo, Maria ; Foss, Stian ; Landsverk, Ole J. B. ; Pinto, Débora ; Szyroki, Alexander ; de Haard, Hans J. ; Saunders, Michael ; Vanlandschoot, Peter ; Sandlie, Inger
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2013, Vol.3 (1), p.1118-1118, Article 1118
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ArticlesPeer ReviewedFull Text
The NHance® Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients
Author / Creator:Aftimos, Philippe ; Rolfo, Christian ; Rottey, Sylvie ; Barthélémy, Philippe ; Borg, Christophe ; Park, Keunchil ; Oh, Do-Youn ; Kim, Sang-We ; De Jonge, Natalie ; Hanssens, Valérie ; Zwanenpoel, Karen ; Molthoff, Carla ; Vugts, Daniëlle ; Dreier, Torsten ; Verheesen, Peter ; van Dongen, Guus A.M.S. ; Jacobs, Julie ; Van Rompaey, Luc ; Hultberg, Anna ; Michieli, Paolo ; Pauwels, Patrick ; Fung, Samson ; Thibault, Alain ; de Haard, Hans ; Leupin, Nicolas ; Awada, Ahmad
Publisher:Basel: MDPI AG
Journal title:Biomedicines, 2021-06, Vol.9 (6), p.665
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ArticlesPeer ReviewedFull Text
Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses
Author / Creator:Spinelli, Silvia ; Desmyter, Aline ; Verrips, C Theo ; de Haard, Hans J W ; Moineau, Sylvain ; Cambillau, Christian
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2006-01, Vol.13 (1), p.85-89
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ArticlesPeer ReviewedFull Text
Lactobacillli expressing llama VHH fragments neutralise Lactococcus phages
Author / Creator:Hultberg, Anna ; Tremblay, Denise M ; de Haard, Hans ; Verrips, Theo ; Moineau, Sylvain ; Hammarström, Lennart ; Marcotte, Harold
Publisher:England: BioMed Central Ltd
Journal title:BMC biotechnology, 2007-09, Vol.7 (1), p.58-58
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Select record 32
Newsletter articlesFull Text
De Haard Hans, Leupin Nicolas, Ochsenbein Adrian, Riether Carsten and Van Rompaey Luc Seek Patent for Treatment for Acute Myeloid Leukemia
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Medical Patent News, 2019
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Newsletter articlesFull Text
U.S. Patent and Trademark Office Releases Percier Jean-Michel, Blanchetot Christophe, Saunders Michael, De Haard Hans, Van Der Woning Sebastian, Persson Emma, Lambrecht Bart, Savvides Savvas, Hammad H...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2019
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Select record 34
ArticlesPeer ReviewedFull Text
Crystal structure of the neutralizing Llama V(HH) D7 and its mode of HIV-1 gp120 interaction
Author / Creator:Hinz, Andreas ; Lutje Hulsik, David ; Forsman, Anna ; Koh, Willie Wee-Lee ; Belrhali, Hassan ; Gorlani, Andrea ; de Haard, Hans ; Weiss, Robin A ; Verrips, Theo ; Weissenhorn, Winfried
Publisher:United States: Public Library of Science (PLoS)
Journal title:PloS one, 2010-05, Vol.5 (5), p.e10482
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ArticlesPeer ReviewedFull Text
Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method
Author / Creator:Flieswasser, Tal ; Camara-Clayette, Valérie ; Danu, Alina ; Bosq, Jacques ; Ribrag, Vincent ; Zabrocki, Piotr ; Van Rompaey, Luc ; de Haard, Hans ; Zwaenepoel, Karen ; Smits, Evelien ; Pauwels, Patrick ; Jacobs, Julie
Publisher:Basel: MDPI AG
Journal title:Cancers, 2019-10, Vol.11 (10), p.1611
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ArticlesPeer ReviewedFull Text
Four individually druggable MET hotspots mediate HGF-driven tumor progression
Author / Creator:Basilico, Cristina ; Hultberg, Anna ; Blanchetot, Christophe ; de Jonge, Natalie ; Festjens, Els ; Hanssens, Valérie ; Osepa, Sjudry-Ilona ; De Boeck, Gitte ; Mira, Alessia ; Cazzanti, Manuela ; Morello, Virginia ; Dreier, Torsten ; Saunders, Michael ; de Haard, Hans ; Michieli, Paolo
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2014-07, Vol.124 (7), p.3172-3186
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ArticlesPeer ReviewedFull Text
Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans
Author / Creator:Ulrichts, Peter ; Guglietta, Antonio ; Dreier, Torsten ; Bragt, Tonke van ; Hanssens, Valérie ; Hofman, Erik ; Vankerckhoven, Bernhardt ; Verheesen, Peter ; Ongenae, Nicolas ; Lykhopiy, Valentina ; Enriquez, F Javier ; Cho, JunHaeng ; Ober, Raimund J ; Ward, E Sally ; de Haard, Hans ; Leupin, Nicolas
Publisher:Ann Arbor: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2018-10, Vol.128 (10), p.4372-4386
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Select record 38
ArticlesPeer ReviewedFull Text
Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models
Author / Creator:Dewulf, Jonatan ; Flieswasser, Tal ; Delahaye, Tim ; Vangestel, Christel ; Miranda, Alan ; de Haard, Hans ; Jacobs, Julie ; Smits, Evelien ; Van den Wyngaert, Tim ; Elvas, Filipe
Publisher:England
Journal title:EJNMMI radiopharmacy and chemistry, 2023-04, Vol.8 (1), p.8
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ArticlesPeer ReviewedFull Text
Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy
Author / Creator:Godar, Marie ; Morello, Virginia ; Sadi, Ava ; Hultberg, Anna ; De Jonge, Natalie ; Basilico, Cristina ; Hanssens, Valérie ; Saunders, Michael ; Lambrecht, Bart N. ; El Khattabi, Mohamed ; de Haard, Hans ; Michieli, Paolo ; Blanchetot, Christophe
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-08, Vol.6 (1), p.31621-31621, Article 31621
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Select record 40
ArticlesPeer ReviewedFull Text
Neutralisation of HIV-1 cell-cell spread by human and llama antibodies
Author / Creator:McCoy, Laura E ; Groppelli, Elisabetta ; Blanchetot, Christophe ; de Haard, Hans ; Verrips, Theo ; Rutten, Lucy ; Weiss, Robin A ; Jolly, Clare
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2014-10, Vol.11 (1), p.83-83, Article 83
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The CD70-CD27 axis in oncology: the new kids on the block

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A human APOC3 missense variant and monoclonal antibody accelerate apoC-III clearance and lower triglyceride-rich lipoprotein levels

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The Fab region of IgG impairs the internalization pathway of FcRn upon Fc engagement

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Efficient inhibition of EGFR signalling and of tumour growth by antagonistic anti-EGFR Nanobodies

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Llama antibody fragments recognizing various epitopes of the CD4bs neutralize a broad range of HIV-1 subtypes A, B and C

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VHH-Photosensitizer Conjugates for Targeted Photodynamic Therapy of Met-Overexpressing Tumor Cells

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Site-specific 68Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

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Selection of Nanobodies that Target Human Neonatal Fc Receptor

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The NHance® Mutation-Equipped Anti-MET Antibody ARGX-111 Displays Increased Tissue Penetration and Anti-Tumor Activity in Advanced Cancer Patients

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Lactococcal bacteriophage p2 receptor-binding protein structure suggests a common ancestor gene with bacterial and mammalian viruses

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Lactobacillli expressing llama VHH fragments neutralise Lactococcus phages

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De Haard Hans, Leupin Nicolas, Ochsenbein Adrian, Riether Carsten and Van Rompaey Luc Seek Patent for Treatment for Acute Myeloid Leukemia

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U.S. Patent and Trademark Office Releases Percier Jean-Michel, Blanchetot Christophe, Saunders Michael, De Haard Hans, Van Der Woning Sebastian, Persson Emma, Lambrecht Bart, Savvides Savvas, Hammad H...

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Crystal structure of the neutralizing Llama V(HH) D7 and its mode of HIV-1 gp120 interaction

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Screening a Broad Range of Solid and Haematological Tumour Types for CD70 Expression Using a Uniform IHC Methodology as Potential Patient Stratification Method

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Four individually druggable MET hotspots mediate HGF-driven tumor progression

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Neonatal Fc receptor antagonist efgartigimod safely and sustainably reduces IgGs in humans

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Site-specific 68 Ga-labeled nanobody for PET imaging of CD70 expression in preclinical tumor models

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Dual anti-idiotypic purification of a novel, native-format biparatopic anti-MET antibody with improved in vitro and in vivo efficacy

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Neutralisation of HIV-1 cell-cell spread by human and llama antibodies

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