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Select record 21
ArticlesPeer ReviewedFull Text
Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis
Author / Creator:Vig, Balvinder S ; Lorenzi, Philip J ; Mittal, Sachin ; Landowski, Christopher P ; Shin, Ho-Chul ; Mosberg, Henry I ; Hilfinger, John M ; Amidon, Gordon L
Publisher:United States: Springer Nature B.V
Journal title:Pharmaceutical research, 2003-09, Vol.20 (9), p.1381-1388
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Highly regioselective galactosylation of floxuridine catalyzed by β-galactosidase from bovine liver
Author / Creator:Zeng, Quan-Ming ; Li, Ning ; Zong, Min-Hua
Publisher:Dordrecht: Dordrecht : Springer Netherlands
Journal title:Biotechnology letters, 2010-09, Vol.32 (9), p.1251-1254
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Increase of [18F]FLT Tumor Uptake In Vivo Mediated by FdUrd: Toward Improving Cell Proliferation Positron Emission Tomography
Author / Creator:Viertl, David ; Bischof Delaloye, Angelika ; Lanz, Bernard ; Poitry-Yamate, Carole ; Gruetter, Rolf ; Mlynarik, Vladimir ; Ametamey, Simon M. ; Ross, Tobias L. ; Lehr, Hans-Anton ; André, Pierre-Alain ; Perillo-Adamer, Florence ; Kosinski, Marek ; Dupertuis, Yves M. ; Buchegger, Franz
Publisher:New York: Springer-Verlag
Journal title:Molecular imaging and biology, 2011-04, Vol.13 (2), p.321-331
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Unexpected reversal of the regioselectivity in Thermomyces lanuginosus lipase-catalyzed acylation of floxuridine
Author / Creator:Li, Ning ; Zong, Min-Hua ; Ma, Ding
Publisher:Dordrecht: Dordrecht : Springer Netherlands
Journal title:Biotechnology letters, 2009-08, Vol.31 (8), p.1241-1244
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Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC
Author / Creator:Maier, S ; Strasser, S ; Saiko, P ; Leisser, C ; Sasgary, S ; Grusch, M ; Madlener, S ; Bader, Y ; Hartmann, J ; Schott, H ; Mader, R M ; Szekeres, T ; Fritzer-Szekeres, M ; Krupitza, G
Publisher:Netherlands: Springer Nature B.V
Journal title:Apoptosis (London), 2006-03, Vol.11 (3), p.427-440
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Antiviral Activities and Phosphorylation of 5-halo-2'-Deoxyuridines and N-Methanocarbathymidine in Cells Infected with Vaccinia Virus
Author / Creator:Smee, Donald F ; Humphreys, Daniel E ; Hurst, Brett L ; Barnard, Dale L
Publisher:London, England: SAGE Publications
Journal title:Antiviral chemistry & chemotherapy, 2008-02, Vol.19 (1), p.15-24
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Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines
Author / Creator:PATEL, Manish ; AGARWAL, Ram ; ARDALAN, Bach
Publisher:Berlin: Springer
Journal title:Journal of cancer research and clinical oncology, 2004-08, Vol.130 (8), p.453-459
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Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver
Author / Creator:OZAWA, Shogo ; HAMADA, Masashi ; MURAYAMA, Norie ; NAKAJIMA, Yukiko ; KANIWA, Nahoko ; MATSUMOTO, Yoshiaki ; FUKUOKA, Masamichi ; SAWADA, Jun-Ichi ; OHNO, Yasuo
Publisher:Berlin: Springer
Journal title:Cancer chemotherapy and pharmacology, 2002-12, Vol.50 (6), p.454-458
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Intra-aortal therapy with 5-fluorouracil-polyethylene glycol stealth liposomes : Does the metabolism of 5-fluorouracil into 5-fluoro-2'-deoxyuridine depend on pH value? An animal study in VX-2 liver t...
Author / Creator:POHLEN, U ; BINNENHEI, M ; RESZKA, R ; BUHR, H. J ; BERGER, G
Publisher:Basel: Karger
Journal title:Chemotherapy (Basel), 2004-06, Vol.50 (2), p.67-75
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Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored by [19F]-nuclear magnetic resonance spectroscopy in vivo
Author / Creator:PORT, R ; HANISCH, F ; BECKER, M ; BACHERT, P ; ZELLER, J
Publisher:Berlin: Springer
Journal title:Cancer chemotherapy and pharmacology, 1999, Vol.44 (1), p.65-73
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Effect of coadministered uridine on intestinal first-pass metabolism of 5'-deoxy-5-fluorouridine in conscious rats : An evaluation by method of portal-systemic concentration difference
Author / Creator:SAWAI, Y ; YAMAOKA, K ; NAKAGAWA, T
Publisher:New York, NY: Springer
Journal title:Pharmaceutical research, 1998-07, Vol.15 (7), p.1007-1011
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Select record 32
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Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine
Author / Creator:Ninomiya, Yasuyuki ; Miwa, Masanori ; Eda, Hiroyuki ; Sahara, Hiroshi ; Fujimoto, Kaori ; Ishida, Masako ; Umeda, Isao ; Yokose, Kazuteru ; Ishitsuka, Hideo
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 1990-02, Vol.81 (2), p.188-195
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Select record 33
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5-fluorodeoxyuridine as an Alternative to the Synthesis of Mixed Hybridization Probes for the Detection of Specific Gene Sequences
Author / Creator:Habener, Joel F. ; Vo, Chon D. ; Le, Dinh B. ; Gryan, Gary P. ; Ercolani, Louis ; Andrew H.-J. Wang
Publisher:Washington, DC: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1988-03, Vol.85 (6), p.1735-1739
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Select record 34
ArticlesPeer ReviewedFull Text
In vivo Antitumor Effects of Fluoropyrimidines on Colon Adenocarcinoma 38 and Enhancement by Leucovorin
Author / Creator:Iigo, Masaaki ; Nishikata, Ken‐ichi ; Hoshi, Akio
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 1992-04, Vol.83 (4), p.392-396
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Select record 35
ArticlesPeer ReviewedFull Text
Thymidylate Synthetase Purified to Homogeneity from Human Leukemic Cells
Author / Creator:Lockshin, Arnold ; Moran, Richard G. ; Danenberg, Peter V.
Publisher:United States: National Academy of Sciences of the United States of America
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1979-02, Vol.76 (2), p.750-754
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Select record 36
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Competitive Binding Radioassay for the Determination of 5‐Fluorodeoxyuridine and 5‐Fluorodeoxyuridine‐5′‐monophosphate Levels in Plasma and Tumor Tissue
Author / Creator:Miyata, Seiji ; Mikami, Hidetada ; Tai, Masaru ; Hori, Takako ; Fujita, Hiroshi
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 1991-06, Vol.82 (6), p.742-746
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Select record 37
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Ribose‐transfer Activity from Uridine to 5‐Fluorouracil in Ehrlich Ascites Tumor Cells
Author / Creator:Nabeya, Yoshihiro ; Isono, Kaichi ; Moriyama, Yoichi ; Fujimura, Shinji
Publisher:Oxford, UK: Blackwell Publishing Ltd
Journal title:Cancer science, 1990-06, Vol.81 (6‐7), p.692-700
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Select record 38
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Incorporation of intermediary products of 5-FU anabolism into colorectal cancer
Author / Creator:Giles, G R ; Woodhouse, L ; Finan, P J ; Chisholm, E M
Publisher:London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 1986-02, Vol.27 (2), p.176-181
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Select record 39
ArticlesPeer ReviewedFull Text
5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates
Author / Creator:Fernandes, D J ; Bertino, J R
Publisher:United States: National Acad Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 1980-10, Vol.77 (10), p.5663-5667
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Select record 40
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Cause of Deficient DNA Synthesis in Generation 1 of X-Irradiated HeLa Cells
Author / Creator:Hopwood, L. E.
Publisher:United States: Academic Press, Inc
Journal title:Radiation research, 1974-06, Vol.58 (3), p.349-360
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Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis

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Highly regioselective galactosylation of floxuridine catalyzed by β-galactosidase from bovine liver

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Increase of [18F]FLT Tumor Uptake In Vivo Mediated by FdUrd: Toward Improving Cell Proliferation Positron Emission Tomography

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Unexpected reversal of the regioselectivity in Thermomyces lanuginosus lipase-catalyzed acylation of floxuridine

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Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC

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Antiviral Activities and Phosphorylation of 5-halo-2'-Deoxyuridines and N-Methanocarbathymidine in Cells Infected with Vaccinia Virus

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Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines

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Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver

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Intra-aortal therapy with 5-fluorouracil-polyethylene glycol stealth liposomes : Does the metabolism of 5-fluorouracil into 5-fluoro-2'-deoxyuridine depend on pH value? An animal study in VX-2 liver t...

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Local disposition kinetics of floxuridine after intratumoral and subcutaneous injection as monitored by [19F]-nuclear magnetic resonance spectroscopy in vivo

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Effect of coadministered uridine on intestinal first-pass metabolism of 5'-deoxy-5-fluorouridine in conscious rats : An evaluation by method of portal-systemic concentration difference

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Comparative Antitumor Activity and Intestinal Toxicity of 5′‐Deoxy‐5‐fluorouridine and Its Prodrug Trimethoxybenzoyl‐5′‐deoxy‐5‐fluorocytidine

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5-fluorodeoxyuridine as an Alternative to the Synthesis of Mixed Hybridization Probes for the Detection of Specific Gene Sequences

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In vivo Antitumor Effects of Fluoropyrimidines on Colon Adenocarcinoma 38 and Enhancement by Leucovorin

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Thymidylate Synthetase Purified to Homogeneity from Human Leukemic Cells

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Competitive Binding Radioassay for the Determination of 5‐Fluorodeoxyuridine and 5‐Fluorodeoxyuridine‐5′‐monophosphate Levels in Plasma and Tumor Tissue

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Ribose‐transfer Activity from Uridine to 5‐Fluorouracil in Ehrlich Ascites Tumor Cells

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Incorporation of intermediary products of 5-FU anabolism into colorectal cancer

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5-fluorouracil-methotrexate synergy: enhancement of 5-fluorodeoxyridylate binding to thymidylate synthase by dihydropteroylpolyglutamates

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Cause of Deficient DNA Synthesis in Generation 1 of X-Irradiated HeLa Cells

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