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ArticlesPeer ReviewedFull Text
Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells
Author / Creator:Hoffmann, Michèle J. ; Meneceur, Sarah ; Hommel, Katrin ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:Switzerland: MDPI AG
Journal title:Genes, 2021-02, Vol.12 (2), p.260
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Many Different LINE-1 Retroelements Are Activated in Bladder Cancer
Author / Creator:Whongsiri, Patcharawalai ; Goering, Wolfgang ; Lautwein, Tobias ; Hader, Christiane ; Niegisch, Günter ; Köhrer, Karl ; Hoffmann, Michèle J. ; Schulz, Wolfgang A.
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2020-12, Vol.21 (24), p.9433
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Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines
Author / Creator:Hölscher, Alexander S. ; Schulz, Wolfgang A. ; Pinkerneil, Maria ; Niegisch, Günter ; Hoffmann, Michèle J.
Publisher:Germany: BioMed Central Ltd
Journal title:Clinical epigenetics, 2018-01, Vol.10 (1), p.1-14, Article 1
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ArticlesPeer ReviewedFull Text
Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer
Author / Creator:Olah, Csilla ; Reis, Henning ; Hoffmann, Michèle J. ; Mairinger, Fabian ; Ting, Saskia ; Hadaschik, Boris ; Krafft, Ulrich ; Grünwald, Viktor ; Nyirady, Peter ; Varadi, Melinda ; Győrffy, Balázs ; Kiss, Andras ; Szekely, Eszter ; Sjödahl, Gottfrid ; Szarvas, Tibor
Publisher:United States: John Wiley & Sons, Inc
Journal title:Cancer medicine (Malden, MA), 2023-03, Vol.12 (5), p.5222-5232
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Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells
Author / Creator:Koutsogiannouli, Evangelia A. ; Wagner, Nicholas ; Hader, Christiane ; Pinkerneil, Maria ; Hoffmann, Michèle J. ; Schulz, Wolfgang A.
Publisher:Switzerland: MDPI
Journal title:International journal of molecular sciences, 2017-07, Vol.18 (7), p.1449
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A Novel Pipeline for Drug Repurposing for Bladder Cancer Based on Patients’ Omics Signatures
Author / Creator:Mokou, Marika ; Lygirou, Vasiliki ; Angelioudaki, Ioanna ; Paschalidis, Nikolaos ; Stroggilos, Rafael ; Frantzi, Maria ; Latosinska, Agnieszka ; Bamias, Aristotelis ; Hoffmann, Michèle J. ; Mischak, Harald ; Vlahou, Antonia
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2020-11, Vol.12 (12), p.3519
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ArticlesPeer ReviewedFull Text
Differential DNA Methylation of THOR and hTAPAS in the Regulation of hTERT and the Diagnosis of Cancer
Author / Creator:Ott, Pauline ; Araúzo-Bravo, Marcos J. ; Hoffmann, Michèle J. ; Poyet, Cedric ; Bendhack, Marcelo L. ; Santourlidis, Simeon ; Erichsen, Lars
Publisher:Basel: MDPI AG
Journal title:Cancers, 2022-09, Vol.14 (18), p.4384
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Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1
Author / Creator:Erichsen, Lars ; Seifert, Hans-Helge ; Schulz, Wolfgang A. ; Hoffmann, Michèle J. ; Niegisch, Günter ; Araúzo-Bravo, Marcos J. ; Bendhack, Marcelo L. ; Poyet, Cedric ; Hermanns, Thomas ; Beermann, Agnes ; Hassan, Mohamed ; Theis, Lisa ; Mahmood, Wardah ; Santourlidis, Simeon
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-03, Vol.10 (1), p.3808, Article 3808
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Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines
Author / Creator:Skowron, Margaretha ; Niegisch, Günter ; Albrecht, Philipp ; Van Koeveringe, Gommert ; Romano, Andrea ; Albers, Peter ; Schulz, Wolfgang ; Hoffmann, Michèle
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2017-08, Vol.18 (8), p.1680
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Select record 30
ArticlesPeer ReviewedFull Text
Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression
Author / Creator:Jaguva Vasudevan, Ananda Ayyappan ; Hoffmann, Michèle J. ; Poschmann, Gereon ; Petzsch, Patrick ; Wiek, Constanze ; Stühler, Kai ; Köhrer, Karl ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:London: Nature Publishing Group UK
Journal title:Scientific data, 2022-05, Vol.9 (1), p.240-240, Article 240
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ArticlesPeer ReviewedFull Text
HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition
Author / Creator:Jaguva Vasudevan, Ananda Ayyappan ; Hoffmann, Michèle J. ; Beck, Michael L. C. ; Poschmann, Gereon ; Petzsch, Patrick ; Wiek, Constanze ; Stühler, Kai ; Köhrer, Karl ; Schulz, Wolfgang A. ; Niegisch, Günter
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2019-04, Vol.20 (9), p.2135
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ArticlesPeer ReviewedFull Text
Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines
Author / Creator:Skowron, Margaretha A. ; Petzsch, Patrick ; Hardt, Karin ; Wagner, Nicholas ; Beier, Manfred ; Stepanow, Stefanie ; Drechsler, Matthias ; Rieder, Harald ; Köhrer, Karl ; Niegisch, Günter ; Hoffmann, Michèle J. ; Schulz, Wolfgang A.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.14476-14, Article 14476
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Select record 33
ArticlesPeer ReviewedFull Text
Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment
Author / Creator:Thy, Sophia ; Hommel, Alexandra ; Meneceur, Sarah ; Bartkowiak, Anna L. ; Schulz, Wolfgang A. ; Niegisch, Günter ; Hoffmann, Michèle J.
Publisher:Switzerland: MDPI
Journal title:Cancers, 2021-03, Vol.13 (6), p.1376
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ArticlesPeer ReviewedFull Text
CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma
Author / Creator:Klümper, Niklas ; Ralser, Damian J ; Zarbl, Romina ; Schlack, Katrin ; Schrader, Andres Jan ; Rehlinghaus, Marc ; Hoffmann, Michèle J ; Niegisch, Günter ; Uhlig, Annemarie ; Trojan, Lutz ; Steinestel, Julie ; Steinestel, Konrad ; Wirtz, Ralph M ; Sikic, Danijel ; Eckstein, Markus ; Kristiansen, Glen ; Toma, Marieta ; Hölzel, Michael ; Ritter, Manuel ; Strieth, Sebastian ; Ellinger, Jörg ; Dietrich, Dimo
Publisher:England: BMJ Publishing Group LTD
Journal title:Journal for immunotherapy of cancer, 2021-08, Vol.9 (8), p.e002949
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ArticlesPeer ReviewedFull Text
Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines
Author / Creator:Skowron, Margaretha A. ; Niegisch, Günter ; Fritz, Gerhard ; Arent, Tanja ; van Roermund, Joep G. H. ; Romano, Andrea ; Albers, Peter ; Schulz, Wolfgang A. ; Hoffmann, Michèle J.
Publisher:England: BioMed Central Ltd
Journal title:Journal of experimental & clinical cancer research, 2015-11, Vol.34 (1), p.144-144, Article 144
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Select record 36
ArticlesPeer ReviewedFull Text
MMP-7 Serum and Tissue Levels Are Associated with Poor Survival in Platinum-Treated Bladder Cancer Patients
Author / Creator:Szarvas, Tibor ; Hoffmann, Michèle J. ; Olah, Csilla ; Szekely, Eszter ; Kiss, Andras ; Hess, Jochen ; Tschirdewahn, Stephan ; Hadaschik, Boris ; Grotheer, Vera ; Nyirady, Peter ; Csizmarik, Anita ; Varadi, Melinda ; Reis, Henning
Publisher:Switzerland: MDPI AG
Journal title:Diagnostics (Basel), 2020-12, Vol.11 (1), p.48
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Soluble Syndecan-1 Levels Are Associated with Survival in Platinum-Treated Bladder Cancer Patients
Author / Creator:Olah, Csilla ; Tschirdewahn, Stephan ; Hoffmann, Michèle J. ; Krafft, Ulrich ; Hadaschik, Boris ; Nyirady, Peter ; Szendröi, Attila ; Módos, Orsolya ; Csizmarik, Anita ; Kovalszky, Ilona ; Reis, Henning ; Szarvas, Tibor
Publisher:MDPI
Journal title:Diagnostics (Basel), 2020-10, Vol.10 (11), p.864
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Select record 38
ArticlesPeer ReviewedFull Text
Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors
Author / Creator:Hoffmann, Michèle ; Dehn, Judith ; Droop, Johanna ; Niegisch, Günter ; Niedworok, Christian ; Szarvas, Tibor ; Schulz, Wolfgang
Publisher:Switzerland: MDPI AG
Journal title:Non-coding RNA, 2015-12, Vol.1 (3), p.266-284
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Select record 39
ArticlesPeer ReviewedFull Text
Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer
Author / Creator:Wu, Qiong ; Hoffmann, Michèle J ; Hartmann, Florian H ; Schulz, Wolfgang A
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2005-05, Vol.4 (1), p.16-16, Article 16
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Select record 40
ArticlesPeer ReviewedFull Text
Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer
Author / Creator:Schulz, Wolfgang A ; Alexa, Adrian ; Jung, Volker ; Hader, Christiane ; Hoffmann, Michèle J ; Yamanaka, Masanori ; Fritzsche, Sandy ; Wlazlinski, Agnes ; Müller, Mirko ; Lengauer, Thomas ; Engers, Rainer ; Florl, Andrea R ; Wullich, Bernd ; Rahnenführer, Jörg
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2007-02, Vol.6 (1), p.14-14
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Showing 21 to 40 of 44 results

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Downregulation of Cell Cycle and Checkpoint Genes by Class I HDAC Inhibitors Limits Synergism with G2/M Checkpoint Inhibitor MK-1775 in Bladder Cancer Cells

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Many Different LINE-1 Retroelements Are Activated in Bladder Cancer

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Combined inhibition of BET proteins and class I HDACs synergistically induces apoptosis in urothelial carcinoma cell lines

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Predictive value of molecular subtypes and APOBEC3G for adjuvant chemotherapy in urothelial bladder cancer

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Differential Effects of Histone Acetyltransferase GCN5 or PCAF Knockdown on Urothelial Carcinoma Cells

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A Novel Pipeline for Drug Repurposing for Bladder Cancer Based on Patients’ Omics Signatures

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Differential DNA Methylation of THOR and hTAPAS in the Regulation of hTERT and the Diagnosis of Cancer

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Basic Hallmarks of Urothelial Cancer Unleashed in Primary Uroepithelium by Interference with the Epigenetic Master Regulator ODC1

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Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines

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Proteomic and transcriptomic profiles of human urothelial cancer cells with histone deacetylase 5 overexpression

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HDAC5 Expression in Urothelial Carcinoma Cell Lines Inhibits Long-Term Proliferation but Can Promote Epithelial-to-Mesenchymal Transition

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Distinctive mutational spectrum and karyotype disruption in long-term cisplatin-treated urothelial carcinoma cell lines

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Epigenetic Treatment of Urothelial Carcinoma Cells Sensitizes to Cisplatin Chemotherapy and PARP Inhibitor Treatment

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CTLA4 promoter hypomethylation is a negative prognostic biomarker at initial diagnosis but predicts response and favorable outcome to anti-PD-1 based immunotherapy in clear cell renal cell carcinoma

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Phenotype plasticity rather than repopulation from CD90/CK14+ cancer stem cells leads to cisplatin resistance of urothelial carcinoma cell lines

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MMP-7 Serum and Tissue Levels Are Associated with Poor Survival in Platinum-Treated Bladder Cancer Patients

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Soluble Syndecan-1 Levels Are Associated with Survival in Platinum-Treated Bladder Cancer Patients

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Truncated Isoforms of lncRNA ANRIL Are Overexpressed in Bladder Cancer, But Do Not Contribute to Repression of INK4 Tumor Suppressors

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Amplification and overexpression of the ID4 gene at 6p22.3 in bladder cancer

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Factor interaction analysis for chromosome 8 and DNA methylation alterations highlights innate immune response suppression and cytoskeletal changes in prostate cancer

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