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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores
Author / Creator:Allan, Lindsey A. ; Corno, Andrea ; Valverde, Juan Manuel ; Toth, Rachel ; Ly, Tony ; Saurin, Adrian T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-03, Vol.16 (1), p.3069-15, Article 3069
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Cryo-EM structure of the Hippo signaling integrator human STRIPAK
Author / Creator:Jeong, Byung-Cheon ; Bae, Sung Jun ; Ni, Lisheng ; Zhang, Xuewu ; Bai, Xiao-chen ; Luo, Xuelian
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2021-03, Vol.28 (3), p.290-299
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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis
Author / Creator:Bian, Chao ; Guo, Xiaoyu ; Zhang, Yi ; Wang, Lu ; Xu, Tongda ; DeLong, Alison ; Dong, Juan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2020-06, Vol.117 (23), p.13127-13137
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Phosphatase PP2A is requisite for the function of regulatory T cells
Author / Creator:Apostolidis, Sokratis A ; Rodríguez-Rodríguez, Noé ; Suárez-Fueyo, Abel ; Dioufa, Nikolina ; Ozcan, Esra ; Crispín, José C ; Tsokos, Maria G ; Tsokos, George C
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2016-05, Vol.17 (5), p.556-564
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Structural basis of Integrator-dependent RNA polymerase II termination
Author / Creator:Fianu, Isaac ; Ochmann, Moritz ; Walshe, James L. ; Dybkov, Olexandr ; Cruz, Joseph Neos ; Urlaub, Henning ; Cramer, Patrick
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2024-05, Vol.629 (8010), p.219-227
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Cancer-Associated Mutations in Endometriosis without Cancer
Author / Creator:Anglesio, Michael S ; Papadopoulos, Nickolas ; Ayhan, Ayse ; Nazeran, Tayyebeh M ; Noë, Michaël ; Horlings, Hugo M ; Lum, Amy ; Jones, Siân ; Senz, Janine ; Seckin, Tamer ; Ho, Julie ; Wu, Ren-Chin ; Lac, Vivian ; Ogawa, Hiroshi ; Tessier-Cloutier, Basile ; Alhassan, Rami ; Wang, Amy ; Wang, Yuxuan ; Cohen, Joshua D ; Wong, Fontayne ; Hasanovic, Adnan ; Orr, Natasha ; Zhang, Ming ; Popoli, Maria ; McMahon, Wyatt ; Wood, Laura D ; Mattox, Austin ; Allaire, Catherine ; Segars, James ; Williams, Christina ; Tomasetti, Cristian ; Boyd, Niki ; Kinzler, Kenneth W ; Gilks, C. Blake ; Diaz, Luis ; Wang, Tian-Li ; Vogelstein, Bert ; Yong, Paul J ; Huntsman, David G ; Shih, Ie-Ming
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2017-05, Vol.376 (19), p.1835-1848
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In vivo discovery of immunotherapy targets in the tumour microenvironment
Author / Creator:Zhou, Penghui ; Shaffer, Donald R. ; Alvarez Arias, Diana A. ; Nakazaki, Yukoh ; Pos, Wouter ; Torres, Alexis J. ; Cremasco, Viviana ; Dougan, Stephanie K. ; Cowley, Glenn S. ; Elpek, Kutlu ; Brogdon, Jennifer ; Lamb, John ; Turley, Shannon J. ; Ploegh, Hidde L. ; Root, David E. ; Love, J. Christopher ; Dranoff, Glenn ; Hacohen, Nir ; Cantor, Harvey ; Wucherpfennig, Kai W.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-02, Vol.506 (7486), p.52-57
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ArticlesPeer ReviewedFull Text
Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification
Author / Creator:Hein, Jamin B ; Nguyen, Hieu T ; Garvanska, Dimitriya H ; Nasa, Isha ; Kruse, Thomas ; Feng, Yinnian ; Lopez Mendez, Blanca ; Davey, Norman ; Kettenbach, Arminja N ; Fordyce, Polly M ; Nilsson, Jakob
Publisher:England: EMBO Press
Journal title:Molecular systems biology, 2023-12, Vol.19 (12), p.e11782-n/a
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ArticlesPeer ReviewedFull Text
Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer
Author / Creator:Janghorban, Mahnaz ; Farrell, Amy S. ; Allen-Petersen, Brittany L. ; Pelz, Carl ; Daniel, Colin J. ; Oddo, Jessica ; Langer, Ellen M. ; Christensen, Dale J. ; Sears, Rosalie C.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (25), p.9157-9162
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ArticlesPeer ReviewedFull Text
Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A
Author / Creator:Gharbi-Ayachi, Aicha ; Labbé, Jean-Claude ; Burgess, Andrew ; Vigneron, Suzanne ; Strub, Jean-Marc ; Brioudes, Estelle ; Van-Dorsselaer, Alain ; Castro, Anna ; Lorca, Thierry
Publisher:Washington, DC: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2010-12, Vol.330 (6011), p.1673-1677
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Structural basis of host protein hijacking in human T-cell leukemia virus integration
Author / Creator:Bhatt, Veer ; Shi, Ke ; Salamango, Daniel J. ; Moeller, Nicholas H. ; Pandey, Krishan K. ; Bera, Sibes ; Bohl, Heather O. ; Kurniawan, Fredy ; Orellana, Kayo ; Zhang, Wei ; Grandgenett, Duane P. ; Harris, Reuben S. ; Sundborger-Lunna, Anna C. ; Aihara, Hideki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.3121-3121, Article 3121
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ArticlesPeer ReviewedFull Text
The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division
Author / Creator:Lemonnier, Tom ; Daldello, Enrico Maria ; Poulhe, Robert ; Le, Tran ; Miot, Marika ; Lignières, Laurent ; Jessus, Catherine ; Dupré, Aude
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-03, Vol.12 (1), p.1837-16, Article 1837
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The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers
Author / Creator:Fujiki, Hirota ; Sueoka, Eisaburo ; Watanabe, Tatsuro ; Suganuma, Masami
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2018-12, Vol.144 (12), p.2339-2349
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Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes
Author / Creator:Zhong, Yifei ; Lee, Kyung ; Deng, Yueyi ; Ma, Yueming ; Chen, Yiping ; Li, Xueling ; Wei, Chengguo ; Yang, Shumin ; Wang, Tianming ; Wong, Nicholas J. ; Muwonge, Alecia N. ; Azeloglu, Evren U. ; Zhang, Weijia ; Das, Bhaskar ; He, John Cijiang ; Liu, Ruijie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-10, Vol.10 (1), p.4523-15, Article 4523
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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A
Author / Creator:Wong, Pui-Mun ; Feng, Yan ; Wang, Junru ; Shi, Rong ; Jiang, Xuejun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-08, Vol.6 (1), p.8048-8048, Article 8048
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Quantitative interaction proteomics using mass spectrometry
Author / Creator:Wepf, Alexander ; Glatter, Timo ; Schmidt, Alexander ; Aebersold, Ruedi ; Gstaiger, Matthias
Publisher:New York: Nature Publishing Group US
Journal title:Nature methods, 2009-03, Vol.6 (3), p.203-205
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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth
Author / Creator:Sangodkar, Jaya ; Perl, Abbey ; Tohme, Rita ; Kiselar, Janna ; Kastrinsky, David B. ; Zaware, Nilesh ; Izadmehr, Sudeh ; Mazhar, Sahar ; Wiredja, Danica D. ; O’Connor, Caitlin M. ; Hoon, Divya ; Dhawan, Neil S. ; Schlatzer, Daniela ; Yao, Shen ; Leonard, Daniel ; Borczuk, Alain C. ; Gokulrangan, Giridharan ; Wang, Lifu ; Svenson, Elena ; Farrington, Caroline C. ; Yuan, Eric ; Avelar, Rita A. ; Stachnik, Agnes ; Smith, Blake ; Gidwani, Vickram ; Giannini, Heather M. ; McQuaid, Daniel ; McClinch, Kimberly ; Wang, Zhizhi ; Levine, Alice C. ; Sears, Rosalie C. ; Chen, Edward Y. ; Duan, Qiaonan ; Datt, Manish ; Haider, Shozeb ; Ma’ayan, Avi ; DiFeo, Analisa ; Sharma, Neelesh ; Galsky, Matthew D. ; Brautigan, David L. ; Ioannou, Yiannis A. ; Xu, Wenqing ; Chance, Mark R. ; Ohlmeyer, Michael ; Narla, Goutham
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2017-06, Vol.127 (6), p.2081-2090
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RETRACTED: MicroRNA-527 Induces Proliferation and Cell Cycle in Esophageal Squamous Cell Carcinoma Cells by Repressing PH Domain Leucine-Rich-Repeats Protein Phosphatase 2
Author / Creator:Xian, Qingjie ; Zhao, Ronglei ; Fu, Juanjuan
Publisher:Los Angeles, CA: SAGE Publications
Journal title:Dose-response, 2020-04, Vol.18 (2)
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Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2
Author / Creator:Ramesh, Sangeetha ; Morrell, Craig N. ; Tarango, Cristina ; Thomas, Gail D. ; Yuhanna, Ivan S. ; Girardi, Guillermina ; Herz, Joachim ; Urbanus, Rolf T. ; de Groot, Philip G. ; Thorpe, Philip E. ; Salmon, Jane E. ; Shaul, Philip W. ; Mineo, Chieko
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2011-01, Vol.121 (1), p.120-131
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Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration
Author / Creator:Lee, Mi-Sun ; Wan, Jin ; Goldman, Daniel
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2020-05, Vol.9
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A chemical-genetic system to rapidly inhibit the PP2A-B56 phosphatase reveals a role at metaphase kinetochores

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Cryo-EM structure of the Hippo signaling integrator human STRIPAK

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Protein phosphatase 2A promotes stomatal development by stabilizing SPEECHLESS in Arabidopsis

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Phosphatase PP2A is requisite for the function of regulatory T cells

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Structural basis of Integrator-dependent RNA polymerase II termination

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Cancer-Associated Mutations in Endometriosis without Cancer

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In vivo discovery of immunotherapy targets in the tumour microenvironment

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Phosphatase specificity principles uncovered by MRBLE:Dephos and global substrate identification

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Targeting c-MYC by antagonizing PP2A inhibitors in breast cancer

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Substrate of Greatwall Kinase, Arpp19, Controls Mitosis by Inhibiting Protein Phosphatase 2A

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Structural basis of host protein hijacking in human T-cell leukemia virus integration

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The M-phase regulatory phosphatase PP2A-B55δ opposes protein kinase A on Arpp19 to initiate meiotic division

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The concept of the okadaic acid class of tumor promoters is revived in endogenous protein inhibitors of protein phosphatase 2A, SET and CIP2A, in human cancers

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Arctigenin attenuates diabetic kidney disease through the activation of PP2A in podocytes

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Regulation of autophagy by coordinated action of mTORC1 and protein phosphatase 2A

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Quantitative interaction proteomics using mass spectrometry

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Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth

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RETRACTED: MicroRNA-527 Induces Proliferation and Cell Cycle in Esophageal Squamous Cell Carcinoma Cells by Repressing PH Domain Leucine-Rich-Repeats Protein Phosphatase 2

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Antiphospholipid antibodies promote leukocyte–endothelial cell adhesion and thrombosis in mice by antagonizing eNOS via β2GPI and apoER2

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Tgfb3 collaborates with PP2A and notch signaling pathways to inhibit retina regeneration

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