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305 results for Spindle+Apparatus+-+genetics

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ArticlesPeer ReviewedFull Text
Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis
Author / Creator:Sacristan, Carlos ; Ahmad, Misbha Ud Din ; Keller, Jenny ; Fermie, Job ; Groenewold, Vincent ; Tromer, Eelco ; Fish, Alexander ; Melero, Roberto ; Carazo, José María ; Klumperman, Judith ; Musacchio, Andrea ; Perrakis, Anastassis ; Kops, Geert JPL
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2018-07, Vol.20 (7), p.800-810
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NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation
Author / Creator:Sun, Mengjie ; Jia, Mingkang ; Ren, He ; Yang, Biying ; Chi, Wangfei ; Xin, Guangwei ; Jiang, Qing ; Zhang, Chuanmao
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7157-7157, Article 7157
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The doublecortin-family kinase ZYG-8DCLK1 regulates microtubule dynamics and motor-driven forces to promote the stability of C. elegans acentrosomal spindles
Author / Creator:Czajkowski, Emily R. ; Zou, Yuntong ; Divekar, Nikita S. ; Wignall, Sarah M.
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS genetics, 2024-09, Vol.20 (9), p.e1011373
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Spindle integrity is regulated by a phospho-dependent interaction between the Ndc80 and Dam1 kinetochore complexes
Author / Creator:Nelson, Christian R. ; Mallett, Darren R. ; Biggins, Sue
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2025-04, Vol.21 (4), p.e1011645
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Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11
Author / Creator:Zadra, Ivan ; Jimenez-Delgado, Senda ; Anglada-Girotto, Miquel ; Segura-Morales, Carolina ; Compton, Zachary J. ; Janke, Carsten ; Serrano, Luis ; Ruprecht, Verena ; Vernos, Isabelle
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-11, Vol.13 (1), p.7147-7147, Article 7147
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Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells
Author / Creator:Ertych, Norman ; Stolz, Ailine ; Stenzinger, Albrecht ; Weichert, Wilko ; Kaulfuß, Silke ; Burfeind, Peter ; Aigner, Achim ; Wordeman, Linda ; Bastians, Holger
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2014-08, Vol.16 (8), p.779-791
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Epithelial junctions maintain tissue architecture by directing planar spindle orientation
Author / Creator:Nakajima, Yu-ichiro ; Meyer, Emily J. ; Kroesen, Amanda ; McKinney, Sean A. ; Gibson, Matthew C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-08, Vol.500 (7462), p.359-362
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The mitotic spindle is chiral due to torques within microtubule bundles
Author / Creator:Novak, Maja ; Polak, Bruno ; Simunić, Juraj ; Boban, Zvonimir ; Kuzmić, Barbara ; Thomae, Andreas W ; Tolić, Iva M ; Pavin, Nenad
Publisher:London: Nature Publishing Group
Journal title:Nature communications, 2018-09, Vol.9, p.1-10
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A monoastral mitotic spindle determines lineage fate and position in the mouse embryo
Author / Creator:Pomp Oz ; Lim Hui Yi Grace ; Skory, Robin M ; Moverley Adam A ; Tetlak Piotr ; Bissiere Stephanie ; Plachta, Nicolas
Publisher:London: Nature Publishing Group
Journal title:Nature cell biology, 2022-02, Vol.24 (2), p.155-167
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The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans
Author / Creator:Polisetty, Satya Dev ; Bhat, Krishna ; Das, Kuladeep ; Clark, Ivan ; Hardwick, Kevin G. ; Sanyal, Kaustuv
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2025-01, Vol.21 (1), p.e1011552
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Negative feedback at kinetochores underlies a responsive spindle checkpoint signal
Author / Creator:Nijenhuis, Wilco ; Vallardi, Giulia ; Teixeira, Antoinette ; Kops, Geert J. P. L. ; Saurin, Adrian T.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2014-12, Vol.16 (12), p.1257-1264
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Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes
Author / Creator:Shapiro, Joanatta G. ; Changela, Neha ; Jang, Janet K. ; Joshi, Jay N. ; McKim, Kim S.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2025-01, Vol.21 (1), p.e1011400
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ArticlesPeer ReviewedFull Text
Cohesin is required for meiotic spindle assembly independent of its role in cohesion in C. elegans
Author / Creator:McNally, Karen P. ; Beath, Elizabeth A. ; Danlasky, Brennan M. ; Barroso, Consuelo ; Gong, Ting ; Li, Wenzhe ; Martinez-Perez, Enrique ; McNally, Francis J.
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2022-10, Vol.18 (10), p.e1010136-e1010136
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ArticlesPeer ReviewedFull Text
Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells
Author / Creator:Tauchman, Eric C. ; Boehm, Frederick J. ; DeLuca, Jennifer G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-12, Vol.6 (1), p.10036-10036, Article 10036
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ArticlesPeer ReviewedFull Text
Chromosome Segregation in Budding Yeast: Sister Chromatid Cohesion and Related Mechanisms
Author / Creator:Marston, Adele L
Publisher:United States: Genetics Society of America
Journal title:Genetics (Austin), 2014-01, Vol.196 (1), p.31-63
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Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips
Author / Creator:Gudimchuk, Nikita ; Vitre, Benjamin ; Kim, Yumi ; Kiyatkin, Anatoly ; Cleveland, Don W. ; Ataullakhanov, Fazly I. ; Grishchuk, Ekaterina L.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-09, Vol.15 (9), p.1079-1088
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WDR62 is associated with the spindle pole and is mutated in human microcephaly
Author / Creator:Nicholas, Adeline K ; Khurshid, Maryam ; Désir, Julie ; Carvalho, Ofélia P ; Cox, James J ; Thornton, Gemma ; Kausar, Rizwana ; Ansar, Muhammad ; Ahmad, Wasim ; Verloes, Alain ; Passemard, Sandrine ; Misson, Jean-Paul ; Lindsay, Susan ; Gergely, Fanni ; Dobyns, William B ; Roberts, Emma ; Abramowicz, Marc ; Woods, C Geoffrey
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2010-11, Vol.42 (11), p.1010-1014
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Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes
Author / Creator:Pfender, Sybille ; Kuznetsov, Vitaliy ; Pasternak, Michał ; Tischer, Thomas ; Santhanam, Balaji ; Schuh, Melina
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-08, Vol.524 (7564), p.239-242
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Cryptococcus neoformans Slu7 ensures nuclear positioning during mitotic progression through RNA splicing
Author / Creator:Krishnan, Vishnu Priya ; Negi, Manendra Singh ; Peesapati, Raghavaram ; Vijayraghavan, Usha
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2024-05, Vol.20 (5), p.e1011272
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RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS
Author / Creator:Dharmadhikari, Avinash V. ; Abad, Maria Alba ; Khan, Sheraz ; Maroofian, Reza ; Sands, Tristan T. ; Ullah, Farid ; Samejima, Itaru ; Shen, Yanwen ; Wear, Martin A. ; Moore, Kiara E. ; Kondakova, Elena ; Mitina, Natalia ; Schaub, Theres ; Lee, Grace K. ; Umandap, Christine H. ; Berger, Sara M. ; Iglesias, Alejandro D. ; Popp, Bernt ; Abou Jamra, Rami ; Gabriel, Heinz ; Rentas, Stefan ; Rippert, Alyssa L. ; Gray, Christopher ; Izumi, Kosuke ; Conlin, Laura K. ; Koboldt, Daniel C. ; Mosher, Theresa Mihalic ; Hickey, Scott E. ; Albert, Dara V. F. ; Norwood, Haley ; Lewanda, Amy Feldman ; Dai, Hongzheng ; Liu, Pengfei ; Mitani, Tadahiro ; Marafi, Dana ; Eker, Hatice Koçak ; Pehlivan, Davut ; Posey, Jennifer E. ; Lippa, Natalie C. ; Vena, Natalie ; Heinzen, Erin L. ; Goldstein, David B. ; Mignot, Cyril ; de Sainte Agathe, Jean-Madeleine ; Al-Sannaa, Nouriya Abbas ; Zamani, Mina ; Sadeghian, Saeid ; Azizimalamiri, Reza ; Seifia, Tahere ; Zaki, Maha S. ; Abdel-Salam, Ghada M. H. ; Abdel-Hamid, Mohamed S. ; Alabdi, Lama ; Alkuraya, Fowzan Sami ; Dawoud, Heba ; Lofty, Aya ; Bauer, Peter ; Zifarelli, Giovanni ; Afzal, Erum ; Zafar, Faisal ; Efthymiou, Stephanie ; Gossett, Daniel ; Towne, Meghan C. ; Yeneabat, Raey ; Perez-Duenas, Belen ; Cazurro-Gutierrez, Ana ; Verdura, Edgard ; Cantarin-Extremera, Veronica ; Marques, Ana do Vale ; Helwak, Aleksandra ; Tollervey, David ; Wontakal, Sandeep N. ; Aggarwal, Vimla S. ; Rosenfeld, Jill A. ; Tarabykin, Victor ; Ohta, Shinya ; Lupski, James R. ; Houlden, Henry ; Earnshaw, William C. ; Davis, Erica E. ; Jeyaprakash, A. Arockia ; Liao, Jun
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-02, Vol.16 (1), p.1703-24
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Showing 21 to 40 of 305 results

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Dynamic kinetochore size regulation promotes microtubule capture and chromosome biorientation in mitosis

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NuMA regulates mitotic spindle assembly, structural dynamics and function via phase separation

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The doublecortin-family kinase ZYG-8DCLK1 regulates microtubule dynamics and motor-driven forces to promote the stability of C. elegans acentrosomal spindles

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Spindle integrity is regulated by a phospho-dependent interaction between the Ndc80 and Dam1 kinetochore complexes

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Chromosome segregation fidelity requires microtubule polyglutamylation by the cancer downregulated enzyme TTLL11

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Increased microtubule assembly rates influence chromosomal instability in colorectal cancer cells

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Epithelial junctions maintain tissue architecture by directing planar spindle orientation

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The mitotic spindle is chiral due to torques within microtubule bundles

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A monoastral mitotic spindle determines lineage fate and position in the mouse embryo

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The dependence of shugoshin on Bub1-kinase activity is dispensable for the maintenance of spindle assembly checkpoint response in Cryptococcus neoformans

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Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

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Distinct checkpoint and homolog biorientation pathways regulate meiosis I in Drosophila oocytes

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Cohesin is required for meiotic spindle assembly independent of its role in cohesion in C. elegans

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Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells

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Chromosome Segregation in Budding Yeast: Sister Chromatid Cohesion and Related Mechanisms

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Kinetochore kinesin CENP-E is a processive bi-directional tracker of dynamic microtubule tips

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WDR62 is associated with the spindle pole and is mutated in human microcephaly

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Live imaging RNAi screen reveals genes essential for meiosis in mammalian oocytes

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Cryptococcus neoformans Slu7 ensures nuclear positioning during mitotic progression through RNA splicing

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RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS

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