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31 results for Westwood,+Nicholas+J

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Select record 21
ArticlesPeer ReviewedFull Text
Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation
Author / Creator:Odell, Anahi V. ; Tran, Fanny ; Foderaro, Jenna E. ; Poupart, Séverine ; Pathak, Ravi ; Westwood, Nicholas J. ; Ward, Gary E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-03, Vol.10 (3), p.e0120331
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Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion
Author / Creator:Leung, Jacqueline M. ; Tran, Fanny ; Pathak, Ravindra B. ; Poupart, Séverine ; Heaslip, Aoife T. ; Ballif, Bryan A. ; Westwood, Nicholas J. ; Ward, Gary E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-06, Vol.9 (6), p.e98056-e98056
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Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib
Author / Creator:Ladds, Marcus J. G. W. ; Pastor-Fernández, Andrés ; Popova, Gergana ; van Leeuwen, Ingeborg M. M. ; Eng, Kai Er ; Drummond, Catherine J. ; Johansson, Lars ; Svensson, Richard ; Westwood, Nicholas J. ; McCarthy, Anna R. ; Tholander, Fredrik ; Popa, Mihaela ; Lane, David P. ; McCormack, Emmet ; McInerney, Gerald M. ; Bhatia, Ravi ; Laín, Sonia
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-04, Vol.13 (4), p.e0195956-e0195956
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Select record 24
ArticlesPeer ReviewedFull Text
A Small-Molecule Approach to Studying Invasive Mechanisms of Toxoplasma gondii
Author / Creator:Carey, Kimberly L. ; Westwood, Nicholas J. ; Mitchison, Timothy J. ; Ward, Gary E. ; Miller, Louis H.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-05, Vol.101 (19), p.7433-7438
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A Modular Approach to Triazole-Containing Chemical Inducers of Dimerisation for Yeast Three-Hybrid Screening
Author / Creator:Tran, Fanny ; Odell, Anahi ; Ward, Gary ; Westwood, Nicholas
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2013-09, Vol.18 (9), p.11639-11657
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Select record 26
ArticlesPeer ReviewedFull Text
A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity
Author / Creator:Heaslip, Aoife T. ; Leung, Jacqueline M. ; Carey, Kimberly L. ; Catti, Federica ; Warshaw, David M. ; Westwood, Nicholas J. ; Ballif, Bryan A. ; Ward, Gary E.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2010-01, Vol.6 (1), p.e1000720-e1000720
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Select record 27
ArticlesPeer ReviewedFull Text
Discovery and Validation of SIRT2 Inhibitors Based on Tenovin-6: Use of a 1H-NMR Method to Assess Deacetylase Activity
Author / Creator:Pirrie, Lisa ; McCarthy, Anna R. ; Major, Louise L. ; Morkūnaitė, Vaida ; Zubrienė, Asta ; Matulis, Daumantas ; Lain, Sonia ; Lebl, Tomas ; Westwood, Nicholas J.
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2012-10, Vol.17 (10), p.12206-12224
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Select record 28
ArticlesPeer ReviewedFull Text
Chemical genetics: how does it function?
Author / Creator:Thompson, J. M. T. ; Westwood, Nicholas J.
Publisher:England: The Royal Society
Journal title:Philosophical transactions of the Royal Society of London. Series A: Mathematical, physical, and engineering sciences, 2004-12, Vol.362 (1825), p.2761-2774
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Select record 29
ArticlesPeer ReviewedFull Text
Valorisation of Natural Resources and the Need for Economic and Sustainability Assessment: The Case of Cocoa Pod Husk in Indonesia
Author / Creator:Picchioni, Fiorella ; Warren, Geoffrey P. ; Lambert, Smilja ; Balcombe, Kelvin ; Robinson, J. Steve ; Srinivasan, Chittur ; D. Gomez, Leonardo ; Faas, Laura ; Westwood, Nicholas J. ; Chatzifragkou, Afroditi ; Charalampopoulos, Dimitris ; Shaw, Liz J.
Publisher:Basel: MDPI AG
Journal title:Sustainability, 2020-11, Vol.12 (21), p.8962
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Select record 30
ArticlesPeer ReviewedFull Text
Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6
Author / Creator:MacCallum, Stephanie F. ; Groves, Michael J. ; James, John ; Murray, Karen ; Appleyard, Virginia ; Prescott, Alan R. ; Drbal, Abed A. ; Nicolaou, Anna ; Cunningham, Joan ; Haydock, Sally ; Ganley, Ian G. ; Westwood, Nicholas J. ; Coates, Philip J. ; Lain, Sonia ; Tauro, Sudhir
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2013-02, Vol.3 (1), p.1275, Article 1275
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Select record 31
ArticlesPeer ReviewedFull Text
A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Author / Creator:Ladds, MJGW ; van, Leeuwen IMM ; Drummond, CJ ; Chu, S ; Healy, AR ; Popova, G ; Fernandez, AP ; Mollick, T ; Darekar, S ; Sedimbi, SK
Journal title:NATURE COMMUNICATIONS, 2018-05, Vol.9 (1)
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Select record 32
ArticlesPeer ReviewedFull Text
Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage
Author / Creator:Ladds, Marcus J. G. W. ; van Leeuwen, Ingeborg M. M. ; Drummond, Catherine J. ; Chu, Su ; Healy, Alan R. ; Popova, Gergana ; Pastor Fernández, Andrés ; Mollick, Tanzina ; Darekar, Suhas ; Sedimbi, Saikiran K. ; Nekulova, Marta ; Sachweh, Marijke C. C. ; Campbell, Johanna ; Higgins, Maureen ; Tuck, Chloe ; Popa, Mihaela ; Safont, Mireia Mayoral ; Gelebart, Pascal ; Fandalyuk, Zinayida ; Thompson, Alastair M. ; Svensson, Richard ; Gustavsson, Anna-Lena ; Johansson, Lars ; Färnegårdh, Katarina ; Yngve, Ulrika ; Saleh, Aljona ; Haraldsson, Martin ; D’Hollander, Agathe C. A. ; Franco, Marcela ; Zhao, Yan ; Håkansson, Maria ; Walse, Björn ; Larsson, Karin ; Peat, Emma M. ; Pelechano, Vicent ; Lunec, John ; Vojtesek, Borivoj ; Carmena, Mar ; Earnshaw, William C. ; McCarthy, Anna R. ; Westwood, Nicholas J. ; Arsenian-Henriksson, Marie ; Lane, David P. ; Bhatia, Ravi ; McCormack, Emmet ; Laín, Sonia
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-05, Vol.9 (1), p.2071-2, Article 2071
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Select record 33
ArticlesPeer ReviewedFull Text
Identification of TgCBAP, a Novel Cytoskeletal Protein that Localizes to Three Distinct Subcompartments of the Toxoplasma gondii Pellicle: e98492
Author / Creator:Tilley, Lucas D ; Krishnamurthy, Shruthi ; Westwood, Nicholas J ; Ward, Gary E
Journal title:PloS one, 2014-06, Vol.9 (6)
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Select record 34
ArticlesPeer ReviewedFull Text
Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation: e0120331
Author / Creator:Odell, Anahi V ; Tran, Fanny ; Foderaro, Jenna E ; Poupart, Severine ; Pathak, Ravi ; Westwood, Nicholas J ; Ward, Gary E
Journal title:PloS one, 2015-03, Vol.10 (3)
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Select record 35
ArticlesPeer ReviewedFull Text
A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity: e1000720
Author / Creator:Heaslip, Aoife T ; Leung, Jacqueline M ; Carey, Kimberly L ; Catti, Federica ; Warshaw, David M ; Westwood, Nicholas J ; Ballif, Bryan A ; Ward, Gary E
Publisher:San Francisco: Public Library of Science
Journal title:PLoS pathogens, 2010-01, Vol.6 (1)
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Select record 36
ArticlesPeer ReviewedFull Text
Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion: e98056
Author / Creator:Leung, Jacqueline M ; Tran, Fanny ; Pathak, Ravindra B ; Poupart, Severine ; Heaslip, Aoife T ; Ballif, Bryan A ; Westwood, Nicholas J ; Ward, Gary E
Journal title:PloS one, 2014-06, Vol.9 (6)
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Select record 37
ArticlesPeer ReviewedFull Text
Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties: e0124481
Author / Creator:Figuera-Losada, Mariana ; Stathis, Marigo ; Dorskind, Joelle M ; Thomas, Ajit G ; Bandaru, Veera VenkataRatnam ; Yoo, Seung-Wan ; Westwood, Nicholas J ; Rogers, Graeme W ; McArthur, Justin C ; Haughey, Norman J
Journal title:PloS one, 2015-05, Vol.10 (5)
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Select record 38
ArticlesPeer ReviewedFull Text
Structure of a specific acyl-enzyme complex formed between β-casomorphin-7 and porcine pancreatic elastase
Author / Creator:Wilmouth, Rupert C. ; Clifton, Ian J. ; Robinson, Carol V. ; Roach, Peter L. ; Aplin, Robin T. ; Westwood, Nicholas J. ; Hajdu, Janos ; Schofield, Christopher J.
Publisher:New York: Nature Publishing Group US
Journal title:Nature Structural Biology, 1997-06, Vol.4 (6), p.456-462
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Showing 21 to 40 of 31 results

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Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation

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Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion

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Autophagic flux blockage by accumulation of weakly basic tenovins leads to elimination of B-Raf mutant tumour cells that survive vemurafenib

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A Small-Molecule Approach to Studying Invasive Mechanisms of Toxoplasma gondii

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A Modular Approach to Triazole-Containing Chemical Inducers of Dimerisation for Yeast Three-Hybrid Screening

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A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity

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Discovery and Validation of SIRT2 Inhibitors Based on Tenovin-6: Use of a 1H-NMR Method to Assess Deacetylase Activity

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Chemical genetics: how does it function?

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Valorisation of Natural Resources and the Need for Economic and Sustainability Assessment: The Case of Cocoa Pod Husk in Indonesia

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Dysregulation of autophagy in chronic lymphocytic leukemia with the small-molecule Sirtuin inhibitor Tenovin-6

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A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

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Publisher Correction: A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage

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Identification of TgCBAP, a Novel Cytoskeletal Protein that Localizes to Three Distinct Subcompartments of the Toxoplasma gondii Pellicle: e98492

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Yeast Three-Hybrid Screen Identifies TgBRADIN/GRA24 as a Negative Regulator of Toxoplasma gondii Bradyzoite Differentiation: e0120331

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A Small-Molecule Inhibitor of T. gondii Motility Induces the Posttranslational Modification of Myosin Light Chain-1 and Inhibits Myosin Motor Activity: e1000720

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Identification of T. gondii Myosin Light Chain-1 as a Direct Target of TachypleginA-2, a Small-Molecule Inhibitor of Parasite Motility and Invasion: e98056

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Cambinol, a Novel Inhibitor of Neutral Sphingomyelinase 2 Shows Neuroprotective Properties: e0124481

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Structure of a specific acyl-enzyme complex formed between β-casomorphin-7 and porcine pancreatic elastase

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