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Select record 21
ArticlesPeer ReviewedFull Text
Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states
Author / Creator:Jaber, Mohammad ; Radwan, Ahmed ; Loyfer, Netanel ; Abdeen, Mufeed ; Sebban, Shulamit ; Khatib, Areej ; Yassen, Hazar ; Kolb, Thorsten ; Zapatka, Marc ; Makedonski, Kirill ; Ernst, Aurelie ; Kaplan, Tommy ; Buganim, Yosef
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-06, Vol.13 (1), p.3475-21, Article 3475
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A novel cloning strategy for one-step assembly of multiplex CRISPR vectors
Author / Creator:Zuckermann, Marc ; Hlevnjak, Mario ; Yazdanparast, Haniyeh ; Zapatka, Marc ; Jones, David T. W. ; Lichter, Peter ; Gronych, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-11, Vol.8 (1), p.17499-8, Article 17499
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Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients
Author / Creator:Öztürk Selcen ; Yashna, Paul ; Afzal Saira ; Gil-Farina, Irene ; Jauch, Anna ; Peter-Martin, Bruch ; Kalter Verena ; Bola, Hanna ; Arseni Lavinia ; Roessner, Philipp M ; Schmidt, Manfred ; Stilgenbauer Stephan ; Dietrich, Sascha ; Lichter, Peter ; Zapatka Marc ; Seiffert Martina
Publisher:London: Nature Publishing Group
Journal title:Leukemia, 2022-02, Vol.36 (2), p.464-475
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Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
Author / Creator:Smirnov, Petr ; Przybilla, Moritz J. ; Simovic-Lorenz, Milena ; Parra, R. Gonzalo ; Susak, Hana ; Ratnaparkhe, Manasi ; Wong, John KL ; Körber, Verena ; Mallm, Jan-Philipp ; Philippos, George ; Sill, Martin ; Kolb, Thorsten ; Kumar, Rithu ; Casiraghi, Nicola ; Okonechnikov, Konstantin ; Ghasemi, David R. ; Maaß, Kendra Korinna ; Pajtler, Kristian W. ; Jauch, Anna ; Korshunov, Andrey ; Höfer, Thomas ; Zapatka, Marc ; Pfister, Stefan M. ; Huber, Wolfgang ; Stegle, Oliver ; Ernst, Aurélie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-11, Vol.15 (1), p.10183-20, Article 10183
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Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL
Author / Creator:Arseni, Lavinia ; Sigismondo, Gianluca ; Yazdanparast, Haniyeh ; Hermansen, Johanne U. ; Mack, Norman ; Ohl, Sibylle ; Kalter, Verena ; Iskar, Murat ; Kalxdorf, Mathias ; Friedel, Dennis ; Rettel, Mandy ; Paul, Yashna ; Ringshausen, Ingo ; Eldering, Eric ; Dubois, Julie ; Kater, Arnon P. ; Zapatka, Marc ; Roessner, Philipp M. ; Tausch, Eugen ; Stilgenbauer, Stephan ; Dietrich, Sascha ; Savitski, Mikhail M. ; Skånland, Sigrid S. ; Krijgsveld, Jeroen ; Lichter, Peter ; Seiffert, Martina
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.1041-16, Article 1041
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Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability
Author / Creator:Smirnov, Petr ; Przybilla, Moritz J. ; Simovic-Lorenz, Milena ; Parra, R. Gonzalo ; Susak, Hana ; Ratnaparkhe, Manasi ; Wong, John KL ; Körber, Verena ; Mallm, Jan-Philipp ; Philippos, George ; Sill, Martin ; Kolb, Thorsten ; Kumar, Rithu ; Casiraghi, Nicola ; Okonechnikov, Konstantin ; Ghasemi, David R. ; Maaß, Kendra Korinna ; Pajtler, Kristian W. ; Jauch, Anna ; Korshunov, Andrey ; Höfer, Thomas ; Zapatka, Marc ; Pfister, Stefan M. ; Huber, Wolfgang ; Stegle, Oliver ; Ernst, Aurélie
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-01, Vol.16 (1), p.1085-1, Article 1085
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Select record 27
ArticlesPeer ReviewedFull Text
Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies
Author / Creator:Rieber, Nora ; Zapatka, Marc ; Lasitschka, Bärbel ; Jones, David ; Northcott, Paul ; Hutter, Barbara ; Jäger, Natalie ; Kool, Marcel ; Taylor, Michael ; Lichter, Peter ; Pfister, Stefan ; Wolf, Stephan ; Brors, Benedikt ; Eils, Roland
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e66621
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Select record 28
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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks
Author / Creator:Mallm, Jan‐Philipp ; Iskar, Murat ; Ishaque, Naveed ; Klett, Lara C ; Kugler, Sabrina J ; Muino, Jose M ; Teif, Vladimir B ; Poos, Alexandra M ; Großmann, Sebastian ; Erdel, Fabian ; Tavernari, Daniele ; Koser, Sandra D ; Schumacher, Sabrina ; Brors, Benedikt ; König, Rainer ; Remondini, Daniel ; Vingron, Martin ; Stilgenbauer, Stephan ; Lichter, Peter ; Zapatka, Marc ; Mertens, Daniel ; Rippe, Karsten
Publisher:London: Nature Publishing Group UK
Journal title:Molecular systems biology, 2019-05, Vol.15 (5), p.e8339-n/a
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Select record 29
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Relevance of PTEN loss in brain metastasis formation in breast cancer patients
Author / Creator:Wikman, Harriet ; Lamszus, Katrin ; Detels, Niclas ; Uslar, Liubov ; Wrage, Michaela ; Benner, Christian ; Hohensee, Ina ; Ylstra, Bauke ; Eylmann, Kathrin ; Zapatka, Marc ; Sauter, Guido ; Kemming, Dirk ; Glatzel, Markus ; Müller, Volkmar ; Westphal, Manfred ; Pantel, Klaus
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2012-03, Vol.14 (2), p.R49-R49, Article R49
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Select record 30
ArticlesPeer ReviewedFull Text
Monitoring CSF Proteome Alterations in Amyotrophic Lateral Sclerosis: Obstacles and Perspectives in Translating a Novel Marker Panel to the Clinic
Author / Creator:von Neuhoff, Nils ; Oumeraci, Tonio ; Wolf, Thomas ; Kollewe, Katja ; Bewerunge, Peter ; Neumann, Boris ; Brors, Benedikt ; Bufler, Johannes ; Wurster, Ulrich ; Schlegelberger, Brigitte ; Dengler, Reinhard ; Zapatka, Marc ; Petri, Susanne
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-09, Vol.7 (9), p.e44401
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Select record 31
ArticlesPeer ReviewedFull Text
Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia
Author / Creator:Juraeva, Dilafruz ; Haenisch, Britta ; Zapatka, Marc ; Frank, Josef ; Witt, Stephanie H. ; Mühleisen, Thomas W. ; Treutlein, Jens ; Strohmaier, Jana ; Meier, Sandra ; Degenhardt, Franziska ; Giegling, Ina ; Ripke, Stephan ; Leber, Markus ; Lange, Christoph ; Schulze, Thomas G. ; Mössner, Rainald ; Nenadic, Igor ; Sauer, Heinrich ; Rujescu, Dan ; Maier, Wolfgang ; Børglum, Anders ; Ophoff, Roel ; Cichon, Sven ; Nöthen, Markus M. ; Rietschel, Marcella ; Mattheisen, Manuel ; Brors, Benedikt
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2014-06, Vol.10 (6), p.e1004345
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Select record 32
ArticlesPeer ReviewedFull Text
Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy
Author / Creator:Ugurel, Selma ; Schrama, David ; Keller, Gunhild ; Schadendorf, Dirk ; Bröcker, Eva-Bettina ; Houben, Roland ; Zapatka, Marc ; Fink, Wolfram ; Kaufman, Howard L. ; Becker, Jürgen C.
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cancer Immunology, Immunotherapy, 2008-05, Vol.57 (5), p.685-691
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Select record 33
ArticlesPeer ReviewedFull Text
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli
Author / Creator:Schramm, Gunnar ; Zapatka, Marc ; Eils, Roland ; König, Rainer
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2007-05, Vol.8 (1), p.149-149, Article 149
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Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5)
Author / Creator:Zboralski, Dirk ; Böckmann, Miriam ; Zapatka, Marc ; Hoppe, Sabine ; Schöneck, Anna ; Hahn, Stephan A ; Schmiegel, Wolff ; Schwarte-Waldhoff, Irmgard
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2008-07, Vol.8 (1), p.215-215, Article 215
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Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms
Author / Creator:König, Rainer ; Schramm, Gunnar ; Oswald, Marcus ; Seitz, Hanna ; Sager, Sebastian ; Zapatka, Marc ; Reinelt, Gerhard ; Eils, Roland
Publisher:England: BioMed Central Ltd
Journal title:BMC bioinformatics, 2006-03, Vol.7 (1), p.119-119, Article 119
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High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix compositi...
Author / Creator:Klein-Scory, Susanne ; Zapatka, Marc ; Eilert-Micus, Christina ; Hoppe, Sabine ; Schwarz, Elisabeth ; Schmiegel, Wolff ; Hahn, Stephan A ; Schwarte-Waldhoff, Irmgard
Publisher:England: BioMed Central Ltd
Journal title:BMC cancer, 2007-11, Vol.7 (1), p.209-209, Article 209
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Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling
Author / Creator:Zuckermann, Marc ; Hovestadt, Volker ; Knobbe-Thomsen, Christiane B. ; Zapatka, Marc ; Northcott, Paul A. ; Schramm, Kathrin ; Belic, Jelena ; Jones, David T. W. ; Tschida, Barbara ; Moriarity, Branden ; Largaespada, David ; Roussel, Martine F. ; Korshunov, Andrey ; Reifenberger, Guido ; Pfister, Stefan M. ; Lichter, Peter ; Kawauchi, Daisuke ; Gronych, Jan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-06, Vol.6 (1), p.7391, Article 7391
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Select record 38
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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma
Author / Creator:Schwartzentruber, Jeremy ; Korshunov, Andrey ; Liu, Xiao-Yang ; Jones, David T. W. ; Pfaff, Elke ; Jacob, Karine ; Sturm, Dominik ; Fontebasso, Adam M. ; Quang, Dong-Anh Khuong ; Tönjes, Martje ; Hovestadt, Volker ; Albrecht, Steffen ; Kool, Marcel ; Nantel, Andre ; Konermann, Carolin ; Lindroth, Anders ; Jäger, Natalie ; Rausch, Tobias ; Ryzhova, Marina ; Korbel, Jan O. ; Hielscher, Thomas ; Hauser, Peter ; Garami, Miklos ; Klekner, Almos ; Bognar, Laszlo ; Ebinger, Martin ; Schuhmann, Martin U. ; Scheurlen, Wolfram ; Pekrun, Arnulf ; Frühwald, Michael C. ; Roggendorf, Wolfgang ; Kramm, Christoph ; Dürken, Matthias ; Atkinson, Jeffrey ; Lepage, Pierre ; Montpetit, Alexandre ; Zakrzewska, Magdalena ; Zakrzewski, Krzystof ; Liberski, Pawel P. ; Dong, Zhifeng ; Siegel, Peter ; Kulozik, Andreas E. ; Zapatka, Marc ; Guha, Abhijit ; Malkin, David ; Felsberg, Jörg ; Reifenberger, Guido ; von Deimling, Andreas ; Ichimura, Koichi ; Collins, V. Peter ; Witt, Hendrik ; Milde, Till ; Witt, Olaf ; Zhang, Cindy ; Castelo-Branco, Pedro ; Lichter, Peter ; Faury, Damien ; Tabori, Uri ; Plass, Christoph ; Majewski, Jacek ; Pfister, Stefan M. ; Jabado, Nada
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-02, Vol.482 (7384), p.226-231
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Active medulloblastoma enhancers reveal subgroup-specific cellular origins
Author / Creator:Lin, Charles Y. ; Erkek, Serap ; Tong, Yiai ; Yin, Linlin ; Federation, Alexander J. ; Zapatka, Marc ; Haldipur, Parthiv ; Kawauchi, Daisuke ; Risch, Thomas ; Warnatz, Hans-Jörg ; Worst, Barbara C. ; Ju, Bensheng ; Orr, Brent A. ; Zeid, Rhamy ; Polaski, Donald R. ; Segura-Wang, Maia ; Waszak, Sebastian M. ; Jones, David T. W. ; Kool, Marcel ; Hovestadt, Volker ; Buchhalter, Ivo ; Sieber, Laura ; Johann, Pascal ; Chavez, Lukas ; Gröschel, Stefan ; Ryzhova, Marina ; Korshunov, Andrey ; Chen, Wenbiao ; Chizhikov, Victor V. ; Millen, Kathleen J. ; Amstislavskiy, Vyacheslav ; Lehrach, Hans ; Yaspo, Marie-Laure ; Eils, Roland ; Lichter, Peter ; Korbel, Jan O. ; Pfister, Stefan M. ; Bradner, James E. ; Northcott, Paul A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-02, Vol.530 (7588), p.57-62
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Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
Author / Creator:Jones, David T W ; Hutter, Barbara ; Jäger, Natalie ; Korshunov, Andrey ; Kool, Marcel ; Warnatz, Hans-Jörg ; Zichner, Thomas ; Lambert, Sally R ; Ryzhova, Marina ; Quang, Dong Anh Khuong ; Fontebasso, Adam M ; Stütz, Adrian M ; Hutter, Sonja ; Zuckermann, Marc ; Sturm, Dominik ; Gronych, Jan ; Lasitschka, Bärbel ; Schmidt, Sabine ; Şeker-Cin, Huriye ; Witt, Hendrik ; Sultan, Marc ; Ralser, Meryem ; Northcott, Paul A ; Hovestadt, Volker ; Bender, Sebastian ; Pfaff, Elke ; Stark, Sebastian ; Faury, Damien ; Schwartzentruber, Jeremy ; Majewski, Jacek ; Weber, Ursula D ; Zapatka, Marc ; Raeder, Benjamin ; Schlesner, Matthias ; Worth, Catherine L ; Bartholomae, Cynthia C ; von Kalle, Christof ; Imbusch, Charles D ; Radomski, Sylwester ; Lawerenz, Chris ; van Sluis, Peter ; Koster, Jan ; Volckmann, Richard ; Versteeg, Rogier ; Lehrach, Hans ; Monoranu, Camelia ; Winkler, Beate ; Unterberg, Andreas ; Herold-Mende, Christel ; Milde, Till ; Kulozik, Andreas E ; Ebinger, Martin ; Schuhmann, Martin U ; Cho, Yoon-Jae ; Pomeroy, Scott L ; von Deimling, Andreas ; Witt, Olaf ; Taylor, Michael D ; Wolf, Stephan ; Karajannis, Matthias A ; Eberhart, Charles G ; Scheurlen, Wolfram ; Hasselblatt, Martin ; Ligon, Keith L ; Kieran, Mark W ; Korbel, Jan O ; Yaspo, Marie-Laure ; Brors, Benedikt ; Felsberg, Jörg ; Reifenberger, Guido ; Collins, V Peter ; Jabado, Nada ; Eils, Roland ; Lichter, Peter
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2013-08, Vol.45 (8), p.927-932
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Comparative parallel multi-omics analysis during the induction of pluripotent and trophectoderm states

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A novel cloning strategy for one-step assembly of multiplex CRISPR vectors

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Longitudinal analyses of CLL in mice identify leukemia-related clonal changes including a Myc gain predicting poor outcome in patients

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Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability

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Longitudinal omics data and preclinical treatment suggest the proteasome inhibitor carfilzomib as therapy for ibrutinib-resistant CLL

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Author Correction: Multi-omic and single-cell profiling of chromothriptic medulloblastoma reveals genomic and transcriptomic consequences of genome instability

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Coverage Bias and Sensitivity of Variant Calling for Four Whole-genome Sequencing Technologies

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Linking aberrant chromatin features in chronic lymphocytic leukemia to transcription factor networks

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Relevance of PTEN loss in brain metastasis formation in breast cancer patients

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Monitoring CSF Proteome Alterations in Amyotrophic Lateral Sclerosis: Obstacles and Perspectives in Translating a Novel Marker Panel to the Clinic

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Integrated Pathway-Based Approach Identifies Association between Genomic Regions at CTCF and CACNB2 and Schizophrenia

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Impact of the CCR5 gene polymorphism on the survival of metastatic melanoma patients receiving immunotherapy

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Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation of Escherichia coli

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Divergent mechanisms underlie Smad4-mediated positive regulation of the three genes encoding the basement membrane component laminin-332 (laminin-5)

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Discovering functional gene expression patterns in the metabolic network of Escherichia coli with wavelets transforms

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High-level inducible Smad4-reexpression in the cervical cancer cell line C4-II is associated with a gene expression profile that predicts a preferential role of Smad4 in extracellular matrix compositi...

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Somatic CRISPR/Cas9-mediated tumour suppressor disruption enables versatile brain tumour modelling

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Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

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Active medulloblastoma enhancers reveal subgroup-specific cellular origins

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Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

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