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Select record 41
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A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation
Author / Creator:Fedeles, Sorin V ; Tian, Xin ; Gallagher, Anna-Rachel ; Mitobe, Michihiro ; Nishio, Saori ; Lee, Seung Hun ; Cai, Yiqiang ; Geng, Lin ; Crews, Craig M ; Somlo, Stefan
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-07, Vol.43 (7), p.639-647
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New treatment paradigms for ADPKD: moving towards precision medicine
Author / Creator:Lanktree, Matthew B. ; Chapman, Arlene B.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Nephrology, 2017-12, Vol.13 (12), p.750-768
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Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases
Author / Creator:Uno, Takaya ; Hosomi, Kouichi ; Yokoyama, Satoshi
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-10, Vol.14 (1), p.25943-10, Article 25943
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Reversing polycystic kidney disease
Author / Creator:Boletta, Alessandra
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2021-12, Vol.53 (12), p.1623-1624
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Select record 45
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The cilia protein IFT88 is required for spindle orientation in mitosis
Author / Creator:Delaval, Benedicte ; Bright, Alison ; Lawson, Nathan D. ; Doxsey, Stephen
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2011-04, Vol.13 (4), p.461-468
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Select record 46
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Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression
Author / Creator:Yang, Chaozhe ; Harafuji, Naoe ; O’Connor, Amber K. ; Kesterson, Robert A. ; Watts, Jacob A. ; Majmundar, Amar J. ; Braun, Daniela A. ; Lek, Monkol ; Laricchia, Kristen M. ; Fathy, Hanan M. ; Mane, Shrikant ; Shril, Shirlee ; Hildebrandt, Friedhelm ; Guay-Woodford, Lisa M.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-09, Vol.11 (1), p.18274-18274, Article 18274
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A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells
Author / Creator:Asawa, Rosita R. ; Danchik, Carina ; Zakharov, Alexey ; Chen, Yuchi ; Voss, Ty ; Jadhav, Ajit ; Wallace, Darren P. ; Trott, Josephine F. ; Weiss, Robert H. ; Simeonov, Anton ; Martinez, Natalia J.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-03, Vol.10 (1), p.4203-4203, Article 4203
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Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models
Author / Creator:Natoli, Thomas A ; Smith, Laurie A ; Rogers, Kelly A ; Wang, Bing ; Komarnitsky, Svetlana ; Budman, Yeva ; Belenky, Alexei ; Bukanov, Nikolay O ; Dackowski, William R ; Husson, Hervé ; Russo, Ryan J ; Shayman, James A ; Ledbetter, Steven R ; Leonard, John P ; Ibraghimov-Beskrovnaya, Oxana
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2010-07, Vol.16 (7), p.788-792
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Select record 49
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The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease
Author / Creator:Jamadar, Abeda ; Suma, Sreenath M. ; Mathew, Sijo ; Fields, Timothy A. ; Wallace, Darren P. ; Calvet, James P. ; Rao, Reena
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-10, Vol.12 (10), p.947-8, Article 947
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Translational research in ADPKD: lessons from animal models
Author / Creator:Happé, Hester ; Peters, Dorien J. M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Nephrology, 2014-10, Vol.10 (10), p.587-601
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Renal denervation does not affect hypertension or the renin-angiotensin system in a rodent model of juvenile-onset polycystic kidney disease: clinical implications
Author / Creator:Li, Sheran ; Hildreth, Cara M. ; Rahman, Ahmed A. ; Barton, Sean A. ; Wyse, Benjamin F. ; Lim, Chai K. ; Pilowsky, Paul M. ; Phillips, Jacqueline K.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-07, Vol.11 (1), p.14286-16, Article 14286
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Crystal deposition aids cystogenesis: POLYCYSTIC KIDNEY DISEASE
Author / Creator:Allison, Susan J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Nephrology, 2019-12, Vol.15 (12), p.730-730
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Select record 53
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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective
Author / Creator:Kanhai, Anish A. ; Bange, Hester ; Verburg, Lotte ; Dijkstra, Kyra L. ; Price, Leo S. ; Peters, Dorien J. M. ; Leonhard, Wouter N.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2020-02, Vol.10 (1), p.1672-1672, Article 1672
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Early infiltrating macrophage subtype correlates with late-stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease
Author / Creator:Zimmerman, Kurt A. ; Song, Cheng J. ; Aloria, Ernald J.G. ; Li, Zhang ; Zhou, Juling ; Bland, Sarah J. ; Yashchenko, Alex ; Crossman, David K. ; Mrug, Michal ; Yoder, Bradley K.
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2021-10, Vol.101 (10), p.1382-1393
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Select record 55
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Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease
Author / Creator:Zhang, Jennifer Qin Jing ; Burgess, Jane ; Stepanova, Daria ; Saravanabavan, Sayanthooran ; Wong, Annette T.Y. ; Kaldis, Philipp ; Rangan, Gopala K.
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2020-05, Vol.100 (5), p.696-711
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Select record 56
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Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3
Author / Creator:Mitsuhata, Yuto ; Abe, Takaya ; Misaki, Kazuyo ; Nakajima, Yuna ; Kiriya, Keita ; Kawasaki, Miwa ; Kiyonari, Hiroshi ; Takeichi, Masatoshi ; Toya, Mika ; Sato, Masamitsu
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2021-03, Vol.11 (1), p.5857-5857, Article 5857
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Select record 57
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Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD
Author / Creator:Hort, Yvonne ; Sullivan, Patricia ; Wedd, Laura ; Fowles, Lindsay ; Stevanovski, Igor ; Deveson, Ira ; Simons, Cas ; Mallett, Andrew ; Patel, Chirag ; Furlong, Timothy ; Cowley, Mark J. ; Shine, John ; Mallawaarachchi, Amali
Publisher:London: Nature Publishing Group UK
Journal title:Npj genomic medicine, 2023-07, Vol.8 (1), p.16-16, Article 16
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Select record 58
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Molecular diagnostics for autosomal dominant polycystic kidney disease
Author / Creator:Harris, Peter C. ; Rossetti, Sandro
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Nephrology, 2010-04, Vol.6 (4), p.197-206
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Select record 59
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Somatic mutation in autosomal dominant polycystic kidney disease revealed by deep sequencing human kidney cysts
Author / Creator:Mallawaarachchi, Amali C. ; Hort, Yvonne ; Wedd, Laura ; Lo, Kitty ; Senum, Sarah ; Toumari, Mojgan ; Chen, Wenhan ; Utsiwegota, Mike ; Mawson, Jane ; Leslie, Scott ; Laurence, Jerome ; Anderson, Lyndal ; Snelling, Paul ; Salomon, Robert ; Rangan, Gopala K. ; Furlong, Timothy ; Shine, John ; Cowley, Mark J.
Publisher:London: Nature Publishing Group UK
Journal title:Npj genomic medicine, 2024-12, Vol.9 (1), p.69-9, Article 69
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Select record 60
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PKD2 founder mutation is the most common mutation of polycystic kidney disease in Taiwan
Author / Creator:Yu, Chih-Chuan ; Lee, An-Fu ; Kohl, Stefen ; Lin, Ming-Yen ; Cheng, Siao Muk ; Hung, Chi-Chih ; Chang, Jer-Ming ; Chiu, Yi-Wen ; Hwang, Shang-Jyh ; Otto, Edgar A. ; Hildebrandt, Friedhelm ; Hwang, Daw-Yang
Publisher:London: Nature Publishing Group UK
Journal title:Npj genomic medicine, 2022-07, Vol.7 (1), p.40-40, Article 40
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Showing 41 to 60 of 91 results

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A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation

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New treatment paradigms for ADPKD: moving towards precision medicine

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Evaluation of tolvaptan-associated hepatic disorder using different national pharmacovigilance databases

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Reversing polycystic kidney disease

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The cilia protein IFT88 is required for spindle orientation in mitosis

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Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression

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A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells

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Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models

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The tyrosine-kinase inhibitor Nintedanib ameliorates autosomal-dominant polycystic kidney disease

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Translational research in ADPKD: lessons from animal models

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Renal denervation does not affect hypertension or the renin-angiotensin system in a rodent model of juvenile-onset polycystic kidney disease: clinical implications

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Crystal deposition aids cystogenesis: POLYCYSTIC KIDNEY DISEASE

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Renal cyst growth is attenuated by a combination treatment of tolvaptan and pioglitazone, while pioglitazone treatment alone is not effective

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Early infiltrating macrophage subtype correlates with late-stage phenotypic outcome in a mouse model of hepatorenal fibrocystic disease

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Role of cyclin-dependent kinase 2 in the progression of mouse juvenile cystic kidney disease

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Cyst formation in proximal renal tubules caused by dysfunction of the microtubule minus-end regulator CAMSAP3

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Atypical splicing variants in PKD1 explain most undiagnosed typical familial ADPKD

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Molecular diagnostics for autosomal dominant polycystic kidney disease

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Somatic mutation in autosomal dominant polycystic kidney disease revealed by deep sequencing human kidney cysts

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PKD2 founder mutation is the most common mutation of polycystic kidney disease in Taiwan

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