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1,135 results for Plaque,+Amyloid+-+pathology

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Select record 41
ArticlesPeer ReviewedFull Text
Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging
Author / Creator:Füger, Petra ; Hefendehl, Jasmin K ; Veeraraghavalu, Karthik ; Wendeln, Ann-Christin ; Schlosser, Christine ; Obermüller, Ulrike ; Wegenast-Braun, Bettina M ; Neher, Jonas J ; Martus, Peter ; Kohsaka, Shinichi ; Thunemann, Martin ; Feil, Robert ; Sisodia, Sangram S ; Skodras, Angelos ; Jucker, Mathias
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2017-10, Vol.20 (10), p.1371-1376
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ScaleS: an optical clearing palette for biological imaging
Author / Creator:Hama, Hiroshi ; Hioki, Hiroyuki ; Namiki, Kana ; Hoshida, Tetsushi ; Kurokawa, Hiroshi ; Ishidate, Fumiyoshi ; Kaneko, Takeshi ; Akagi, Takumi ; Saito, Takashi ; Saido, Takaomi ; Miyawaki, Atsushi
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2015-10, Vol.18 (10), p.1518-1529
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Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence
Author / Creator:Choi, Insup ; Wang, Minghui ; Yoo, Seungyeul ; Xu, Peng ; Seegobin, Steven P. ; Li, Xianting ; Han, Xian ; Wang, Qian ; Peng, Junmin ; Zhang, Bin ; Yue, Zhenyu
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2023-07, Vol.25 (7), p.963-974
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The amyloid hypothesis on trial
Author / Creator:Makin, Simon
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2018-07, Vol.559 (7715), p.S4-S7
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Select record 45
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Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE
Author / Creator:Parhizkar, Samira ; Arzberger, Thomas ; Brendel, Matthias ; Kleinberger, Gernot ; Deussing, Maximilian ; Focke, Carola ; Nuscher, Brigitte ; Xiong, Monica ; Ghasemigharagoz, Alireza ; Katzmarski, Natalie ; Krasemann, Susanne ; Lichtenthaler, Stefan F. ; Müller, Stephan A. ; Colombo, Alessio ; Monasor, Laura Sebastian ; Tahirovic, Sabina ; Herms, Jochen ; Willem, Michael ; Pettkus, Nadine ; Butovsky, Oleg ; Bartenstein, Peter ; Edbauer, Dieter ; Rominger, Axel ; Ertürk, Ali ; Grathwohl, Stefan A. ; Neher, Jonas J. ; Holtzman, David M. ; Meyer-Luehmann, Melanie ; Haass, Christian
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2019-02, Vol.22 (2), p.191-204
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Select record 46
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Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
Author / Creator:Clark, Christopher M, MD ; Pontecorvo, Michael J, Dr ; Beach, Thomas G, MD ; Bedell, Barry J, MD ; Coleman, R Edward, Prof ; Doraiswamy, P Murali, Prof ; Fleisher, Adam S, MD ; Reiman, Eric M, Prof ; Sabbagh, Marwan N, MD ; Sadowsky, Carl H, Prof ; Schneider, Julie A, MD ; Arora, Anupa, MD ; Carpenter, Alan P, PhD ; Flitter, Matthew L, BA ; Joshi, Abhinay D, MS ; Krautkramer, Michael J, BS ; Lu, Ming, MS ; Mintun, Mark A, MD ; Skovronsky, Daniel M, MD
Publisher:England: Elsevier Ltd
Journal title:Lancet neurology, 2012-08, Vol.11 (8), p.669-678
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Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts
Author / Creator:Nelson, Peter T. ; Brayne, Carol ; Flanagan, Margaret E. ; Abner, Erin L. ; Agrawal, Sonal ; Attems, Johannes ; Castellani, Rudolph J. ; Corrada, Maria M. ; Cykowski, Matthew D. ; Di, Jing ; Dickson, Dennis W. ; Dugger, Brittany N. ; Ervin, John F. ; Fleming, Jane ; Graff-Radford, Jonathan ; Grinberg, Lea T. ; Hokkanen, Suvi R. K. ; Hunter, Sally ; Kapasi, Alifiya ; Kawas, Claudia H. ; Keage, Hannah A. D. ; Keene, C. Dirk ; Kero, Mia ; Knopman, David S. ; Kouri, Naomi ; Kovacs, Gabor G. ; Labuzan, Sydney A. ; Larson, Eric B. ; Latimer, Caitlin S. ; Leite, Renata E. P. ; Matchett, Billie J. ; Matthews, Fiona E. ; Merrick, Richard ; Montine, Thomas J. ; Murray, Melissa E. ; Myllykangas, Liisa ; Nag, Sukriti ; Nelson, Ruth S. ; Neltner, Janna H. ; Nguyen, Aivi T. ; Petersen, Ronald C. ; Polvikoski, Tuomo ; Reichard, R. Ross ; Rodriguez, Roberta D. ; Suemoto, Claudia K. ; Wang, Shih-Hsiu J. ; Wharton, Stephen B. ; White, Lon ; Schneider, Julie A.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2022-07, Vol.144 (1), p.27-44
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Insights into Alzheimer’s disease from single-cell genomic approaches
Author / Creator:Murdock, Mitchell H. ; Tsai, Li-Huei
Publisher:New York: Nature Publishing Group US
Journal title:Nature neuroscience, 2023-02, Vol.26 (2), p.181-195
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Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease
Author / Creator:Nobili, Annalisa ; Latagliata, Emanuele Claudio ; Viscomi, Maria Teresa ; Cavallucci, Virve ; Cutuli, Debora ; Giacovazzo, Giacomo ; Krashia, Paraskevi ; Rizzo, Francesca Romana ; Marino, Ramona ; Federici, Mauro ; De Bartolo, Paola ; Aversa, Daniela ; Dell’Acqua, Maria Concetta ; Cordella, Alberto ; Sancandi, Marco ; Keller, Flavio ; Petrosini, Laura ; Puglisi-Allegra, Stefano ; Mercuri, Nicola Biagio ; Coccurello, Roberto ; Berretta, Nicola ; D’Amelio, Marcello
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-04, Vol.8 (1), p.14727-14727, Article 14727
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Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice
Author / Creator:Hemonnot-Girard, Anne-Laure ; Meersseman, Cédric ; Pastore, Manuela ; Garcia, Valentin ; Linck, Nathalie ; Rey, Catherine ; Chebbi, Amine ; Jeanneteau, Freddy ; Ginsberg, Stephen D ; Lachuer, Joël ; Reynes, Christelle ; Rassendren, François ; Hirbec, Hélène
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2022-09, Vol.19 (1), p.234-26, Article 234
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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice
Author / Creator:Belfiore, Ramona ; Rodin, Alexis ; Ferreira, Eric ; Velazquez, Ramon ; Branca, Caterina ; Caccamo, Antonella ; Oddo, Salvatore
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2019-02, Vol.18 (1), p.e12873-n/a
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Clinical Manifestations
Author / Creator:Veasey, Sigrid C
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 3, p.e090824
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Basic Science and Pathogenesis
Author / Creator:Close, Jennie
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e087488
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Basic Science and Pathogenesis
Author / Creator:Guptarak, Jutatip ; Scaduto, Pietro ; Tumurbaatar, Batbayar ; Jupiter, Daniel ; Taglialatela, Giulio ; Fracassi, Anna
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e087096
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Basic Science and Pathogenesis
Author / Creator:Duchesne, Simon ; Chamberland, Éléonore ; Moravveji, Seyedadel ; Doyon, Nicolas
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e088850
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Basic Science and Pathogenesis
Author / Creator:Sanchez-Molina, Paula ; Brownell, Dillon ; Pratapa, Aditya ; Nikulina, Nadezhda ; Cheikh, Bassem Ben ; Singh, Jasmine ; Bogachuk, Alina ; Chiot, Aude ; Chin, Gregory ; Emberley, Katie ; Crotti, Andrea ; Woltjer, Randall ; Svara, Fabian ; Braubach, Oliver ; Ajami, Bahareh
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e088495
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Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature
Author / Creator:Nelson, Peter T. ; Alafuzoff, Irina ; Bigio, Eileen H. ; Bouras, Constantin ; Braak, Heiko ; Cairns, Nigel J. ; Castellani, Rudolph J. ; Crain, Barbara J. ; Davies, Peter ; Tredici, Kelly Del ; Duyckaerts, Charles ; Frosch, Matthew P. ; Haroutunian, Vahram ; Hof, Patrick R. ; Hulette, Christine M. ; Hyman, Bradley T. ; Iwatsubo, Takeshi ; Jellinger, Kurt A. ; Jicha, Gregory A. ; Kövari, Enikö ; Kukull, Walter A. ; Leverenz, James B. ; Love, Seth ; Mackenzie, Ian R. ; Mann, David M. ; Masliah, Eliezer ; McKee, Ann C. ; Montine, Thomas J. ; Morris, John C. ; Schneider, Julie A. ; Sonnen, Joshua A. ; Thal, Dietmar R. ; Trojanowski, John Q. ; Troncoso, Juan C. ; Wisniewski, Thomas ; Woltjer, Randall L. ; Beach, Thomas G.
Publisher:Hagerstown, MD: American Association of Neuropathologists, Inc
Journal title:Journal of neuropathology and experimental neurology, 2012-05, Vol.71 (5), p.362-381
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Select record 58
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APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading
Author / Creator:Wang, Chanung ; Nambiar, Aishwarya ; Strickland, Michael R ; Lee, Choonghee ; Parhizkar, Samira ; Moore, Alec C ; Musiek, Erik S ; Ulrich, Jason D ; Holtzman, David M
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2023-07, Vol.133 (14)
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Imaging beta amyloid aggregation and iron accumulation in Alzheimer's disease using quantitative susceptibility mapping MRI
Author / Creator:Gong, Nan-Jie ; Dibb, Russell ; Bulk, Marjolein ; van der Weerd, Louise ; Liu, Chunlei
Publisher:United States: Elsevier Inc
Journal title:NeuroImage (Orlando, Fla.), 2019-05, Vol.191, p.176-185
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Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease
Author / Creator:Yan, Ping ; Kim, Ki-Wook ; Xiao, Qingli ; Ma, Xiucui ; Czerniewski, Leah R ; Liu, Haiyan ; Rawnsley, David R ; Yan, Yan ; Randolph, Gwendalyn J ; Epelman, Slava ; Lee, Jin-Moo ; Diwan, Abhinav
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2022-06, Vol.132 (11)
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Microglia turnover with aging and in an Alzheimer's model via long-term in vivo single-cell imaging

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ScaleS: an optical clearing palette for biological imaging

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Autophagy enables microglia to engage amyloid plaques and prevents microglial senescence

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The amyloid hypothesis on trial

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Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE

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Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study

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Frequency of LATE neuropathologic change across the spectrum of Alzheimer’s disease neuropathology: combined data from 13 community-based or population-based autopsy cohorts

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Insights into Alzheimer’s disease from single-cell genomic approaches

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Dopamine neuronal loss contributes to memory and reward dysfunction in a model of Alzheimer’s disease

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Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice

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Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice

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Clinical Manifestations

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Basic Science and Pathogenesis

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Basic Science and Pathogenesis

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Basic Science and Pathogenesis

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Basic Science and Pathogenesis

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Correlation of Alzheimer Disease Neuropathologic Changes With Cognitive Status: A Review of the Literature

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APOE-ε4 synergizes with sleep disruption to accelerate Aβ deposition and Aβ-associated tau seeding and spreading

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Imaging beta amyloid aggregation and iron accumulation in Alzheimer's disease using quantitative susceptibility mapping MRI

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Peripheral monocyte-derived cells counter amyloid plaque pathogenesis in a mouse model of Alzheimer's disease

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