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ArticlesPeer ReviewedFull Text
Targeting the cancer epigenome for therapy
Author / Creator:Jones, Peter A. ; Issa, Jean-Pierre J. ; Baylin, Stephen
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2016-10, Vol.17 (10), p.630-641
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Clinical epigenetics: seizing opportunities for translation
Author / Creator:Berdasco, María ; Esteller, Manel
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2019-02, Vol.20 (2), p.109-127
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Interferons α and β in cancer: therapeutic opportunities from new insights
Author / Creator:Borden, Ernest C.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2019-03, Vol.18 (3), p.219-234
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Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer
Author / Creator:Beltran, Himisha ; Prandi, Davide ; Mosquera, Juan Miguel ; Benelli, Matteo ; Puca, Loredana ; Cyrta, Joanna ; Marotz, Clarisse ; Giannopoulou, Eugenia ; Chakravarthi, Balabhadrapatruni V S K ; Varambally, Sooryanarayana ; Tomlins, Scott A ; Nanus, David M ; Tagawa, Scott T ; Van Allen, Eliezer M ; Elemento, Olivier ; Sboner, Andrea ; Garraway, Levi A ; Rubin, Mark A ; Demichelis, Francesca
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2016-03, Vol.22 (3), p.298-305
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A decade of exploring the cancer epigenome — biological and translational implications
Author / Creator:Baylin, Stephen B. ; Jones, Peter A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2011-10, Vol.11 (10), p.726-734
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Poised epigenetic states and acquired drug resistance in cancer
Author / Creator:Brown, Robert ; Curry, Edward ; Magnani, Luca ; Wilhelm-Benartzi, Charlotte S. ; Borley, Jane
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2014-11, Vol.14 (11), p.747-753
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The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes
Author / Creator:Huether, Robert ; Dong, Li ; Chen, Xiang ; Wu, Gang ; Parker, Matthew ; Wei, Lei ; Ma, Jing ; Edmonson, Michael N. ; Hedlund, Erin K. ; Rusch, Michael C. ; Shurtleff, Sheila A. ; Mulder, Heather L. ; Boggs, Kristy ; Vadordaria, Bhavin ; Cheng, Jinjun ; Yergeau, Donald ; Song, Guangchun ; Becksfort, Jared ; Lemmon, Gordon ; Weber, Catherine ; Cai, Zhongling ; Dang, Jinjun ; Walsh, Michael ; Gedman, Amanda L. ; Faber, Zachary ; Easton, John ; Gruber, Tanja ; Kriwacki, Richard W. ; Partridge, Janet F. ; Ding, Li ; Wilson, Richard K. ; Mardis, Elaine R. ; Mullighan, Charles G. ; Gilbertson, Richard J. ; Baker, Suzanne J. ; Zambetti, Gerard ; Ellison, David W. ; Zhang, Jinghui ; Downing, James R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-04, Vol.5 (1), p.3630-3630, Article 3630
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ArticlesPeer ReviewedFull Text
DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer
Author / Creator:Teschendorff, Andrew E ; Gao, Yang ; Jones, Allison ; Ruebner, Matthias ; Beckmann, Matthias W. ; Wachter, David L. ; Fasching, Peter A. ; Widschwendter, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-01, Vol.7 (1), p.10478-12, Article 10478
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ArticlesPeer ReviewedFull Text
SWI/SNF nucleosome remodellers and cancer
Author / Creator:Wilson, Boris G. ; Roberts, Charles W. M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2011-07, Vol.11 (7), p.481-492
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NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink
Author / Creator:Ulanovskaya, Olesya A ; Zuhl, Andrea M ; Cravatt, Benjamin F
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2013-05, Vol.9 (5), p.300-306
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Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer
Author / Creator:Plass, Christoph ; Pfister, Stefan M. ; Lindroth, Anders M. ; Bogatyrova, Olga ; Claus, Rainer ; Lichter, Peter
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Genetics, 2013-11, Vol.14 (11), p.765-780
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ArticlesPeer ReviewedFull Text
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
Author / Creator:Zuber, Johannes ; Shi, Junwei ; Wang, Eric ; Rappaport, Amy R. ; Herrmann, Harald ; Sison, Edward A. ; Magoon, Daniel ; Qi, Jun ; Blatt, Katharina ; Wunderlich, Mark ; Taylor, Meredith J. ; Johns, Christopher ; Chicas, Agustin ; Mulloy, James C. ; Kogan, Scott C. ; Brown, Patrick ; Valent, Peter ; Bradner, James E. ; Lowe, Scott W. ; Vakoc, Christopher R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-10, Vol.478 (7370), p.524-528
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ArticlesPeer ReviewedFull Text
Cancer epigenetics reaches mainstream oncology
Author / Creator:Rodríguez-Paredes, Manuel ; Esteller, Manel
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2011-03, Vol.17 (3), p.330-339
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Cancer biology and NuRD: a multifaceted chromatin remodelling complex
Author / Creator:Lai, Anne Y. ; Wade, Paul A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2011-08, Vol.11 (8), p.588-596
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ArticlesPeer ReviewedFull Text
Increased methylation variation in epigenetic domains across cancer types
Author / Creator:Hansen, Kasper Daniel ; Timp, Winston ; Bravo, Héctor Corrada ; Sabunciyan, Sarven ; Langmead, Benjamin ; McDonald, Oliver G ; Wen, Bo ; Wu, Hao ; Liu, Yun ; Diep, Dinh ; Briem, Eirikur ; Zhang, Kun ; Irizarry, Rafael A ; Feinberg, Andrew P
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-08, Vol.43 (8), p.768-775
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ArticlesPeer ReviewedFull Text
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types
Author / Creator:Wang, Cheng ; Gu, Yayun ; Zhang, Kai ; Xie, Kaipeng ; Zhu, Meng ; Dai, Ningbin ; Jiang, Yue ; Guo, Xuejiang ; Liu, Mingxi ; Dai, Juncheng ; Wu, Linxiang ; Jin, Guangfu ; Ma, Hongxia ; Jiang, Tao ; Yin, Rong ; Xia, Yankai ; Liu, Li ; Wang, Shouyu ; Shen, Bin ; Huo, Ran ; Wang, Qianghu ; Xu, Lin ; Yang, Liuqing ; Huang, Xingxu ; Shen, Hongbing ; Sha, Jiahao ; Hu, Zhibin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-01, Vol.7 (1), p.10499-12, Article 10499
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ArticlesPeer ReviewedFull Text
Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas
Author / Creator:Wang, P ; Dong, Q ; Zhang, C ; Kuan, P-F ; Liu, Y ; Jeck, W R ; Andersen, J B ; Jiang, W ; Savich, G L ; Tan, T-X ; Auman, J T ; Hoskins, J M ; Misher, A D ; Moser, C D ; Yourstone, S M ; Kim, J W ; Cibulskis, K ; Getz, G ; Hunt, H V ; Thorgeirsson, S S ; Roberts, L R ; Ye, D ; Guan, K-L ; Xiong, Y ; Qin, L-X ; Chiang, D Y
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2013-06, Vol.32 (25), p.3091-3100
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Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains
Author / Creator:Berman, Benjamin P ; Weisenberger, Daniel J ; Aman, Joseph F ; Hinoue, Toshinori ; Ramjan, Zachary ; Liu, Yaping ; Noushmehr, Houtan ; Lange, Christopher P E ; van Dijk, Cornelis M ; Tollenaar, Rob A E M ; Van Den Berg, David ; Laird, Peter W
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2012-01, Vol.44 (1), p.40-46
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ArticlesPeer ReviewedFull Text
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin
Author / Creator:Morin, Ryan D ; Johnson, Nathalie A ; Severson, Tesa M ; Mungall, Andrew J ; An, Jianghong ; Goya, Rodrigo ; Paul, Jessica E ; Boyle, Merrill ; Woolcock, Bruce W ; Kuchenbauer, Florian ; Yap, Damian ; Humphries, R Keith ; Griffith, Obi L ; Shah, Sohrab ; Zhu, Henry ; Kimbara, Michelle ; Shashkin, Pavel ; Charlot, Jean F ; Tcherpakov, Marianna ; Corbett, Richard ; Tam, Angela ; Varhol, Richard ; Smailus, Duane ; Moksa, Michelle ; Zhao, Yongjun ; Delaney, Allen ; Qian, Hong ; Birol, Inanc ; Schein, Jacqueline ; Moore, Richard ; Holt, Robert ; Horsman, Doug E ; Connors, Joseph M ; Jones, Steven ; Aparicio, Samuel ; Hirst, Martin ; Gascoyne, Randy D ; Marra, Marco A
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2010-02, Vol.42 (2), p.181-185
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ArticlesPeer ReviewedFull Text
Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia
Author / Creator:Yan, Xiao-Jing ; Xu, Jie ; Gu, Zhao-Hui ; Pan, Chun-Ming ; Lu, Gang ; Shen, Yang ; Shi, Jing-Yi ; Zhu, Yong-Mei ; Tang, Lin ; Zhang, Xiao-Wei ; Liang, Wen-Xue ; Mi, Jian-Qing ; Song, Huai-Dong ; Li, Ke-Qin ; Chen, Zhu ; Chen, Sai-Juan
Publisher:New York: Nature Publishing Group US
Journal title:Nature genetics, 2011-04, Vol.43 (4), p.309-315
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Targeting the cancer epigenome for therapy

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Clinical epigenetics: seizing opportunities for translation

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Interferons α and β in cancer: therapeutic opportunities from new insights

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Divergent clonal evolution of castration-resistant neuroendocrine prostate cancer

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A decade of exploring the cancer epigenome — biological and translational implications

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Poised epigenetic states and acquired drug resistance in cancer

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The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes

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DNA methylation outliers in normal breast tissue identify field defects that are enriched in cancer

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SWI/SNF nucleosome remodellers and cancer

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NNMT promotes epigenetic remodeling in cancer by creating a metabolic methylation sink

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Mutations in regulators of the epigenome and their connections to global chromatin patterns in cancer

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RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia

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Cancer epigenetics reaches mainstream oncology

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Cancer biology and NuRD: a multifaceted chromatin remodelling complex

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Increased methylation variation in epigenetic domains across cancer types

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Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types

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Mutations in isocitrate dehydrogenase 1 and 2 occur frequently in intrahepatic cholangiocarcinomas and share hypermethylation targets with glioblastomas

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Regions of focal DNA hypermethylation and long-range hypomethylation in colorectal cancer coincide with nuclear lamina–associated domains

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Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin

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Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia

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