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ArticlesPeer ReviewedFull Text
A decade of checkpoint blockade immunotherapy in melanoma: understanding the molecular basis for immune sensitivity and resistance
Author / Creator:Huang, Alexander C. ; Zappasodi, Roberta
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2022-05, Vol.23 (5), p.660-670
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The promise and challenges of immune agonist antibody development in cancer
Author / Creator:Mayes, Patrick A. ; Hance, Kenneth W. ; Hoos, Axel
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2018-07, Vol.17 (7), p.509-527
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ArticlesPeer ReviewedFull Text
Aptamers as targeted therapeutics: current potential and challenges
Author / Creator:Zhou, Jiehua ; Rossi, John
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2017-03, Vol.16 (3), p.181-202
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ArticlesPeer ReviewedFull Text
Passive immunotherapy of viral infections: 'super-antibodies' enter the fray
Author / Creator:Walker, Laura M. ; Burton, Dennis R.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Immunology, 2018-05, Vol.18 (5), p.297-308
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ArticlesPeer ReviewedFull Text
Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins
Author / Creator:Pance, Katarina ; Gramespacher, Josef A. ; Byrnes, James R. ; Salangsang, Fernando ; Serrano, Juan-Antonio C. ; Cotton, Adam D. ; Steri, Veronica ; Wells, James A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2023-02, Vol.41 (2), p.273-281
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ArticlesPeer ReviewedFull Text
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
Author / Creator:Pinto, Dora ; Park, Young-Jun ; Beltramello, Martina ; Walls, Alexandra C. ; Tortorici, M. Alejandra ; Bianchi, Siro ; Jaconi, Stefano ; Culap, Katja ; Zatta, Fabrizia ; De Marco, Anna ; Peter, Alessia ; Guarino, Barbara ; Spreafico, Roberto ; Cameroni, Elisabetta ; Case, James Brett ; Chen, Rita E. ; Havenar-Daughton, Colin ; Snell, Gyorgy ; Telenti, Amalio ; Virgin, Herbert W. ; Lanzavecchia, Antonio ; Diamond, Michael S. ; Fink, Katja ; Veesler, David ; Corti, Davide
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2020-07, Vol.583 (7815), p.290-295
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ArticlesPeer ReviewedFull Text
Strategies and challenges for the next generation of antibody–drug conjugates
Author / Creator:Beck, Alain ; Goetsch, Liliane ; Dumontet, Charles ; Corvaïa, Nathalie
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2017-05, Vol.16 (5), p.315-337
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ArticlesPeer ReviewedFull Text
Machine learning for functional protein design
Author / Creator:Notin, Pascal ; Rollins, Nathan ; Gal, Yarin ; Sander, Chris ; Marks, Debora
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2024-02, Vol.42 (2), p.216-228
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ArticlesPeer ReviewedFull Text
Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space
Author / Creator:Makowski, Emily K. ; Kinnunen, Patrick C. ; Huang, Jie ; Wu, Lina ; Smith, Matthew D. ; Wang, Tiexin ; Desai, Alec A. ; Streu, Craig N. ; Zhang, Yulei ; Zupancic, Jennifer M. ; Schardt, John S. ; Linderman, Jennifer J. ; Tessier, Peter M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-07, Vol.13 (1), p.3788-3788, Article 3788
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ArticlesPeer ReviewedFull Text
Respiratory syncytial virus entry and how to block it
Author / Creator:Battles, Michael B. ; McLellan, Jason S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Microbiology, 2019-04, Vol.17 (4), p.233-245
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ArticlesPeer ReviewedFull Text
A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein
Author / Creator:Kim, Cheolmin ; Ryu, Dong-Kyun ; Lee, Jihun ; Kim, Young-Il ; Seo, Ji-Min ; Kim, Yeon-Gil ; Jeong, Jae-Hee ; Kim, Minsoo ; Kim, Jong-In ; Kim, Pankyeom ; Bae, Jin Soo ; Shim, Eun Yeong ; Lee, Min Seob ; Kim, Man Su ; Noh, Hanmi ; Park, Geun-Soo ; Park, Jae Sang ; Son, Dain ; An, Yongjin ; Lee, Jeong No ; Kwon, Ki-Sung ; Lee, Joo-Yeon ; Lee, Hansaem ; Yang, Jeong-Sun ; Kim, Kyung-Chang ; Kim, Sung Soon ; Woo, Hye-Min ; Kim, Jun-Won ; Park, Man-Seong ; Yu, Kwang-Min ; Kim, Se-Mi ; Kim, Eun-Ha ; Park, Su-Jin ; Jeong, Seong Tae ; Yu, Chi Ho ; Song, Youngjo ; Gu, Se Hun ; Oh, Hanseul ; Koo, Bon-Sang ; Hong, Jung Joo ; Ryu, Choong-Min ; Park, Wan Beom ; Oh, Myoung-don ; Choi, Young Ki ; Lee, Soo-Young
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.288-288, Article 288
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ArticlesPeer ReviewedFull Text
Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge
Author / Creator:Pardi, Norbert ; Secreto, Anthony J. ; Shan, Xiaochuan ; Debonera, Fotini ; Glover, Joshua ; Yi, Yanjie ; Muramatsu, Hiromi ; Ni, Houping ; Mui, Barbara L. ; Tam, Ying K. ; Shaheen, Farida ; Collman, Ronald G. ; Karikó, Katalin ; Danet-Desnoyers, Gwenn A. ; Madden, Thomas D. ; Hope, Michael J. ; Weissman, Drew
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-03, Vol.8 (1), p.14630-8, Article 14630
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ArticlesPeer ReviewedFull Text
Developing therapeutic monoclonal antibodies at pandemic pace
Author / Creator:Kelley, Brian
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2020-05, Vol.38 (5), p.540-545
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ArticlesPeer ReviewedFull Text
A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes
Author / Creator:Guo, Yu ; Huang, Lisu ; Zhang, Guangshun ; Yao, Yanfeng ; Zhou, He ; Shen, Shu ; Shen, Bingqing ; Li, Bo ; Li, Xin ; Zhang, Qian ; Chen, Mingjie ; Chen, Da ; Wu, Jia ; Fu, Dan ; Zeng, Xinxin ; Feng, Mingfang ; Pi, Chunjiang ; Wang, Yuan ; Zhou, Xingdong ; Lu, Minmin ; Li, Yarong ; Fang, Yaohui ; Lu, Yun-Yueh ; Hu, Xue ; Wang, Shanshan ; Zhang, Wanju ; Gao, Ge ; Adrian, Francisco ; Wang, Qisheng ; Yu, Feng ; Peng, Yun ; Gabibov, Alexander G. ; Min, Juan ; Wang, Yuhui ; Huang, Heyu ; Stepanov, Alexey ; Zhang, Wei ; Cai, Yan ; Liu, Junwei ; Yuan, Zhiming ; Zhang, Chen ; Lou, Zhiyong ; Deng, Fei ; Zhang, Hongkai ; Shan, Chao ; Schweizer, Liang ; Sun, Kun ; Rao, Zihe
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-05, Vol.12 (1), p.2623-2623, Article 2623
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ArticlesPeer ReviewedFull Text
An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity
Author / Creator:Weisser, Nina E. ; Sanches, Mario ; Escobar-Cabrera, Eric ; O’Toole, Jason ; Whalen, Elizabeth ; Chan, Peter W. Y. ; Wickman, Grant ; Abraham, Libin ; Choi, Kate ; Harbourne, Bryant ; Samiotakis, Antonios ; Rojas, Andrea Hernández ; Volkers, Gesa ; Wong, Jodi ; Atkinson, Claire E. ; Baardsnes, Jason ; Worrall, Liam J. ; Browman, Duncan ; Smith, Emma E. ; Baichoo, Priya ; Cheng, Chi Wing ; Guedia, Joy ; Kang, Sohyeong ; Mukhopadhyay, Abhishek ; Newhook, Lisa ; Ohrn, Anders ; Raghunatha, Prajwal ; Zago-Schmitt, Matteo ; Schrag, Joseph D. ; Smith, Joel ; Zwierzchowski, Patricia ; Scurll, Joshua M. ; Fung, Vincent ; Black, Sonia ; Strynadka, Natalie C. J. ; Gold, Michael R. ; Presta, Leonard G. ; Ng, Gordon ; Dixit, Surjit
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1394-1394, Article 1394
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ArticlesPeer ReviewedFull Text
Elimination of HIV-1-infected cells by broadly neutralizing antibodies
Author / Creator:Bruel, Timothée ; Guivel-Benhassine, Florence ; Amraoui, Sonia ; Malbec, Marine ; Richard, Léa ; Bourdic, Katia ; Donahue, Daniel Aaron ; Lorin, Valérie ; Casartelli, Nicoletta ; Noël, Nicolas ; Lambotte, Olivier ; Mouquet, Hugo ; Schwartz, Olivier
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-03, Vol.7 (1), p.10844-10844, Article 10844
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ArticlesPeer ReviewedFull Text
Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures
Author / Creator:Eroshenko, Nikolai ; Gill, Taylor ; Keaveney, Marianna K. ; Church, George M. ; Trevejo, Jose M. ; Rajaniemi, Hannu
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2020-07, Vol.38 (7), p.789-791
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ArticlesPeer ReviewedFull Text
The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma
Author / Creator:Senter, Peter D ; Sievers, Eric L
Publisher:New York: Nature Publishing Group US
Journal title:Nature biotechnology, 2012-07, Vol.30 (7), p.631-637
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ArticlesPeer ReviewedFull Text
Myasthenia gravis — autoantibody characteristics and their implications for therapy
Author / Creator:Gilhus, Nils Erik ; Skeie, Geir Olve ; Romi, Fredrik ; Lazaridis, Konstantinos ; Zisimopoulou, Paraskevi ; Tzartos, Socrates
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neurology, 2016-05, Vol.12 (5), p.259-268
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ArticlesPeer ReviewedFull Text
PD-L1hi B cells are critical regulators of humoral immunity
Author / Creator:Khan, Adnan R. ; Hams, Emily ; Floudas, Achilleas ; Sparwasser, Tim ; Weaver, Casey T. ; Fallon, Padraic G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-01, Vol.6 (1), p.5997-5997, Article 5997
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A decade of checkpoint blockade immunotherapy in melanoma: understanding the molecular basis for immune sensitivity and resistance

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The promise and challenges of immune agonist antibody development in cancer

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Aptamers as targeted therapeutics: current potential and challenges

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Passive immunotherapy of viral infections: 'super-antibodies' enter the fray

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Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins

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Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody

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Strategies and challenges for the next generation of antibody–drug conjugates

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Machine learning for functional protein design

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Co-optimization of therapeutic antibody affinity and specificity using machine learning models that generalize to novel mutational space

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Respiratory syncytial virus entry and how to block it

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A therapeutic neutralizing antibody targeting receptor binding domain of SARS-CoV-2 spike protein

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Administration of nucleoside-modified mRNA encoding broadly neutralizing antibody protects humanized mice from HIV-1 challenge

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Developing therapeutic monoclonal antibodies at pandemic pace

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A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes

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An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity

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Elimination of HIV-1-infected cells by broadly neutralizing antibodies

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Implications of antibody-dependent enhancement of infection for SARS-CoV-2 countermeasures

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The discovery and development of brentuximab vedotin for use in relapsed Hodgkin lymphoma and systemic anaplastic large cell lymphoma

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Myasthenia gravis — autoantibody characteristics and their implications for therapy

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PD-L1hi B cells are critical regulators of humoral immunity

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