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ArticlesPeer ReviewedFull Text
Establishment of patient-derived cancer organoids for drug-screening applications
Author / Creator:Driehuis, Else ; Kretzschmar, Kai ; Clevers, Hans
Publisher:London: Nature Publishing Group UK
Journal title:Nature protocols, 2020-10, Vol.15 (10), p.3380-3409
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Mitochondrial RNA modifications shape metabolic plasticity in metastasis
Author / Creator:Delaunay, Sylvain ; Pascual, Gloria ; Feng, Bohai ; Klann, Kevin ; Behm, Mikaela ; Hotz-Wagenblatt, Agnes ; Richter, Karsten ; Zaoui, Karim ; Herpel, Esther ; Münch, Christian ; Dietmann, Sabine ; Hess, Jochen ; Benitah, Salvador Aznar ; Frye, Michaela
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-07, Vol.607 (7919), p.593-603
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ArticlesPeer ReviewedFull Text
Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer
Author / Creator:Galeano Niño, Jorge Luis ; Wu, Hanrui ; LaCourse, Kaitlyn D. ; Kempchinsky, Andrew G. ; Baryiames, Alexander ; Barber, Brittany ; Futran, Neal ; Houlton, Jeffrey ; Sather, Cassie ; Sicinska, Ewa ; Taylor, Alison ; Minot, Samuel S. ; Johnston, Christopher D. ; Bullman, Susan
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2022-11, Vol.611 (7937), p.810-817
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Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response
Author / Creator:Arora, Rohit ; Cao, Christian ; Kumar, Mehul ; Sinha, Sarthak ; Chanda, Ayan ; McNeil, Reid ; Samuel, Divya ; Arora, Rahul K. ; Matthews, T. Wayne ; Chandarana, Shamir ; Hart, Robert ; Dort, Joseph C. ; Biernaskie, Jeff ; Neri, Paola ; Hyrcza, Martin D. ; Bose, Pinaki
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-08, Vol.14 (1), p.5029-5029, Article 5029
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ArticlesPeer ReviewedFull Text
Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes
Author / Creator:Li, Ling ; Cao, Bangrong ; Liang, Xinhua ; Lu, Shun ; Luo, Huaichao ; Wang, Zhaohui ; Wang, Shaoxin ; Jiang, Jian ; Lang, Jinyi ; Zhu, Guiquan
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2019-04, Vol.38 (15), p.2830-2843
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ArticlesPeer ReviewedFull Text
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4
Author / Creator:Wang, Zhiyong ; Wu, Victoria H. ; Allevato, Michael M. ; Gilardi, Mara ; He, Yudou ; Luis Callejas-Valera, Juan ; Vitale-Cross, Lynn ; Martin, Daniel ; Amornphimoltham, Panomwat ; Mcdermott, James ; Yung, Bryan S. ; Goto, Yusuke ; Molinolo, Alfredo A. ; Sharabi, Andrew B. ; Cohen, Ezra E. W. ; Chen, Qianming ; Lyons, J. Guy ; Alexandrov, Ludmil B. ; Gutkind, J. Silvio
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5546-13, Article 5546
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ArticlesPeer ReviewedFull Text
EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial
Author / Creator:de Wit, Jaron G. ; Vonk, Jasper ; Voskuil, Floris J. ; de Visscher, Sebastiaan A. H. J. ; Schepman, Kees-Pieter ; Hooghiemstra, Wouter T. R. ; Linssen, Matthijs D. ; Elias, Sjoerd G. ; Halmos, Gyorgy B. ; Plaat, Boudewijn E. C. ; Doff, Jan J. ; Rosenthal, Eben L. ; Robinson, Dominic ; van der Vegt, Bert ; Nagengast, Wouter B. ; van Dam, Gooitzen M. ; Witjes, Max J. H.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-08, Vol.14 (1), p.4952-4952, Article 4952
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Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups
Author / Creator:Maitra, Arindam ; Biswas, Nidhan K. ; Amin, Kishore ; Kowtal, Pradnya ; Kumar, Shantanu ; Das, Subrata ; Sarin, Rajiv ; Majumder, Partha P. ; Bagchi, I ; Bairagya, B. B. ; Basu, A. ; Bhan, M. K. ; Chaturvedi, P. ; Das, D. ; D’Cruz, A. ; Dhar, R. ; Dutta, D. ; Ganguli, D. ; Gera, P. ; Gupta, T. ; Mahapatra, S. ; Mujawar, M. H. K. ; Mukherjee, S. ; Nair, S. ; Nikam, S. ; Nobre, M. ; Patil, A. ; Patra, S. ; Rama-Gowtham, M. ; Rao, T. S. ; Roy, B. ; Roychowdhury, B. ; Sarkar, D. ; Sarkar, S. ; Sarkar-Roy, N. ; Sutradhar, D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2013-12, Vol.4 (1), p.2873-2873, Article 2873
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ArticlesPeer ReviewedFull Text
Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer
Author / Creator:Carnielli, Carolina Moretto ; Macedo, Carolina Carneiro Soares ; De Rossi, Tatiane ; Granato, Daniela Campos ; Rivera, César ; Domingues, Romênia Ramos ; Pauletti, Bianca Alves ; Yokoo, Sami ; Heberle, Henry ; Busso-Lopes, Ariane Fidelis ; Cervigne, Nilva Karla ; Sawazaki-Calone, Iris ; Meirelles, Gabriela Vaz ; Marchi, Fábio Albuquerque ; Telles, Guilherme Pimentel ; Minghim, Rosane ; Ribeiro, Ana Carolina Prado ; Brandão, Thaís Bianca ; de Castro, Gilberto ; González-Arriagada, Wilfredo Alejandro ; Gomes, Alexandre ; Penteado, Fabio ; Santos-Silva, Alan Roger ; Lopes, Márcio Ajudarte ; Rodrigues, Priscila Campioni ; Sundquist, Elias ; Salo, Tuula ; da Silva, Sabrina Daniela ; Alaoui-Jamali, Moulay A. ; Graner, Edgard ; Fox, Jay W. ; Coletta, Ricardo Della ; Paes Leme, Adriana Franco
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2018-09, Vol.9 (1), p.3598-17, Article 3598
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ArticlesPeer ReviewedFull Text
Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort
Author / Creator:Hutchison, Iain L. ; Ridout, Fran ; Cheung, Sharon M. Y. ; Shah, Neil ; Hardee, Peter ; Surwald, Christian ; Thiruchelvam, Janavikulam ; Cheng, Leo ; Mellor, Tim K. ; Brennan, Peter A. ; Baldwin, Andrew J. ; Shaw, Richard J. ; Halfpenny, Wayne ; Danford, Martin ; Whitley, Simon ; Smith, Graham ; Bailey, Malcolm W. ; Woodwards, Bob ; Patel, Manu ; McManners, Joseph ; Chan, Chi-Hwa ; Burns, Andrew ; Praveen, Prav ; Camilleri, Andrew C. ; Avery, Chris ; Putnam, Graham ; Jones, Keith ; Webster, Keith ; Smith, William P. ; Edge, Colin ; McVicar, Iain ; Grew, Nick ; Hislop, Stuart ; Kalavrezos, Nicholas ; Martin, Ian C. ; Hackshaw, Allan
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2019-11, Vol.121 (10), p.827-836
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ArticlesPeer ReviewedFull Text
Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells
Author / Creator:Duhen, Rebekka ; Ballesteros-Merino, Carmen ; Frye, Alexandra K. ; Tran, Eric ; Rajamanickam, Venkatesh ; Chang, Shu-Ching ; Koguchi, Yoshinobu ; Bifulco, Carlo B. ; Bernard, Brady ; Leidner, Rom S. ; Curti, Brendan D. ; Fox, Bernard A. ; Urba, Walter J. ; Bell, R. Bryan ; Weinberg, Andrew D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-02, Vol.12 (1), p.1047-1047, Article 1047
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ArticlesPeer ReviewedFull Text
Radiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer
Author / Creator:Hutchinson, Marsha-Kay N. D. ; Mierzwa, Michelle ; D’Silva, Nisha J.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2020-04, Vol.39 (18), p.3638-3649
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Partial EMT in head and neck cancer biology: a spectrum instead of a switch
Author / Creator:Pal, Ananya ; Barrett, Thomas F. ; Paolini, Rachel ; Parikh, Anuraag ; Puram, Sidharth V.
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-08, Vol.40 (32), p.5049-5065
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Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma
Author / Creator:Mei, Zi ; Huang, Junwen ; Qiao, Bin ; Lam, Alfred King-yin
Publisher:London: Nature Publishing Group UK
Journal title:International journal of oral science, 2020-05, Vol.12 (1), p.16, Article 16
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Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks
Author / Creator:Halicek, Martin ; Shahedi, Maysam ; Little, James V. ; Chen, Amy Y. ; Myers, Larry L. ; Sumer, Baran D. ; Fei, Baowei
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-10, Vol.9 (1), p.14043-11, Article 14043
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Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma
Author / Creator:Yang, Yixin ; Chen, Dan ; Liu, Huan ; Yang, Kai
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2019-01, Vol.10 (2), p.41, Article 41
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Tumour budding in head and neck cancer: what have we learnt and the next steps towards clinical implementation
Author / Creator:Almangush, Alhadi ; Mäkitie, Antti A. ; Leivo, Ilmo
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2024-01, Vol.130 (1), p.1-2
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The circEPSTI1/mir-942-5p/LTBP2 axis regulates the progression of OSCC in the background of OSF via EMT and the PI3K/Akt/mTOR pathway
Author / Creator:Wang, Jie ; Jiang, Canhua ; Li, Ning ; Wang, Fei ; Xu, Ying ; Shen, Zhengzhong ; Yang, Lina ; Li, Zaiye ; He, Caiyun
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2020-08, Vol.11 (8), p.682-682, Article 682
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Cell death in head and neck cancer pathogenesis and treatment
Author / Creator:Raudenská, Martina ; Balvan, Jan ; Masařík, Michal
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2021-02, Vol.12 (2), p.192-192, Article 192
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Prediction of malignant transformation and recurrence of oral epithelial dysplasia using architectural and cytological feature specific prognostic models
Author / Creator:Mahmood, Hanya ; Bradburn, Mike ; Rajpoot, Nasir ; Islam, Nadim Mohammed ; Kujan, Omar ; Khurram, Syed Ali
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2022-09, Vol.35 (9), p.1151-1159
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Establishment of patient-derived cancer organoids for drug-screening applications

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Mitochondrial RNA modifications shape metabolic plasticity in metastasis

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Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

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Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

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Microenvironmental oxygen pressure orchestrates an anti- and pro-tumoral γδ T cell equilibrium via tumor-derived exosomes

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Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4

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EGFR-targeted fluorescence molecular imaging for intraoperative margin assessment in oral cancer patients: a phase II trial

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Mutational landscape of gingivo-buccal oral squamous cell carcinoma reveals new recurrently-mutated genes and molecular subgroups

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Combining discovery and targeted proteomics reveals a prognostic signature in oral cancer

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Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort

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Neoadjuvant anti-OX40 (MEDI6469) therapy in patients with head and neck squamous cell carcinoma activates and expands antigen-specific tumor-infiltrating T cells

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Radiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer

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Partial EMT in head and neck cancer biology: a spectrum instead of a switch

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Immune checkpoint pathways in immunotherapy for head and neck squamous cell carcinoma

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Head and Neck Cancer Detection in Digitized Whole-Slide Histology Using Convolutional Neural Networks

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Increased expression of lncRNA CASC9 promotes tumor progression by suppressing autophagy-mediated cell apoptosis via the AKT/mTOR pathway in oral squamous cell carcinoma

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Tumour budding in head and neck cancer: what have we learnt and the next steps towards clinical implementation

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The circEPSTI1/mir-942-5p/LTBP2 axis regulates the progression of OSCC in the background of OSF via EMT and the PI3K/Akt/mTOR pathway

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Cell death in head and neck cancer pathogenesis and treatment

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Prediction of malignant transformation and recurrence of oral epithelial dysplasia using architectural and cytological feature specific prognostic models

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