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129 results for 692/4020/4021/288/2032

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ArticlesPeer ReviewedFull Text
Liver regeneration: biological and pathological mechanisms and implications
Author / Creator:Michalopoulos, George K. ; Bhushan, Bharat
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Gastroenterology & hepatology, 2021-01, Vol.18 (1), p.40-55
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ArticlesPeer ReviewedFull Text
Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease
Author / Creator:Bell, Catherine C. ; Hendriks, Delilah F. G. ; Moro, Sabrina M. L. ; Ellis, Ewa ; Walsh, Joanne ; Renblom, Anna ; Fredriksson Puigvert, Lisa ; Dankers, Anita C. A. ; Jacobs, Frank ; Snoeys, Jan ; Sison-Young, Rowena L. ; Jenkins, Rosalind E. ; Nordling, Åsa ; Mkrtchian, Souren ; Park, B. Kevin ; Kitteringham, Neil R. ; Goldring, Christopher E. P. ; Lauschke, Volker M. ; Ingelman-Sundberg, Magnus
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-05, Vol.6 (1), p.25187, Article 25187
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Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver
Author / Creator:Hildebrandt, Franziska ; Andersson, Alma ; Saarenpää, Sami ; Larsson, Ludvig ; Van Hul, Noémi ; Kanatani, Sachie ; Masek, Jan ; Ellis, Ewa ; Barragan, Antonio ; Mollbrink, Annelie ; Andersson, Emma R. ; Lundeberg, Joakim ; Ankarklev, Johan
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-12, Vol.12 (1), p.7046-7046, Article 7046
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ArticlesPeer ReviewedFull Text
Author Correction: Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction
Author / Creator:Du, Kuo ; Umbaugh, David S. ; Wang, Liuyang ; Jun, Ji Hye ; Dutta, Rajesh K. ; Oh, Seh Hoon ; Ren, Niansheng ; Zhang, Qiaojuan ; Ko, Dennis C. ; Ferreira, Ana ; Hill, Jon ; Gao, Guannan ; Pullen, Steven S. ; Jain, Vaibhav ; Gregory, Simon ; Abdelmalek, Manal F. ; Diehl, Anna Mae
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2025-05, Vol.16 (1), p.4195-1, Article 4195
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ArticlesPeer ReviewedFull Text
Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a
Author / Creator:Xu, Yan ; Zhou, Zhuowei ; Kang, Xinmei ; Pan, Lijie ; Liu, Chang ; Liang, Xiaoqi ; Chu, Jiajie ; Dong, Shuai ; Li, Yanli ; Liu, Qiuli ; Sun, Yuetong ; Yu, Shanshan ; Zhang, Qi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-08, Vol.13 (1), p.4555-4555, Article 4555
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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis
Author / Creator:Argemi, Josepmaria ; Latasa, Maria U. ; Atkinson, Stephen R. ; Blokhin, Ilya O. ; Massey, Veronica ; Gue, Joel P. ; Cabezas, Joaquin ; Lozano, Juan J. ; Van Booven, Derek ; Bell, Aaron ; Cao, Sheng ; Vernetti, Lawrence A. ; Arab, Juan P. ; Ventura-Cots, Meritxell ; Edmunds, Lia R. ; Fondevila, Constantino ; Stärkel, Peter ; Dubuquoy, Laurent ; Louvet, Alexandre ; Odena, Gemma ; Gomez, Juan L. ; Aragon, Tomas ; Altamirano, Jose ; Caballeria, Juan ; Jurczak, Michael J. ; Taylor, D. Lansing ; Berasain, Carmen ; Wahlestedt, Claes ; Monga, Satdarshan P. ; Morgan, Marsha Y. ; Sancho-Bru, Pau ; Mathurin, Philippe ; Furuya, Shinji ; Lackner, Carolin ; Rusyn, Ivan ; Shah, Vijay H. ; Thursz, Mark R. ; Mann, Jelena ; Avila, Matias A. ; Bataller, Ramon
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3126-19, Article 3126
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ArticlesPeer ReviewedFull Text
Author Correction: p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1
Author / Creator:Shi, Min Yan ; Yu, Hwang Chan ; Han, Chang Yeob ; Bang, In Hyuk ; Park, Ho Sung ; Jang, Kyu Yun ; Lee, Sangkyu ; Son, Jeong Bum ; Kim, Nam Doo ; Park, Byung-Hyun ; Bae, Eun Ju
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-11, Vol.14 (1), p.7007-7007, Article 7007
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ArticlesPeer ReviewedFull Text
Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration
Author / Creator:Pu, Wenjuan ; Zhang, Hui ; Huang, Xiuzhen ; Tian, Xueying ; He, Lingjuan ; Wang, Yue ; Zhang, Libo ; Liu, Qiaozhen ; Li, Yan ; Li, Yi ; Zhao, Huan ; Liu, Kuo ; Lu, Jie ; Zhou, Yingqun ; Huang, Pengyu ; Nie, Yu ; Yan, Yan ; Hui, Lijian ; Lui, Kathy O. ; Zhou, Bin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-11, Vol.7 (1), p.13369-13369, Article 13369
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ArticlesPeer ReviewedFull Text
Association of Non-alcoholic Fatty Liver Disease with Metabolic Syndrome Independently of Central Obesity and Insulin Resistance
Author / Creator:Yang, Kuen Cheh ; Hung, Hui-Fang ; Lu, Chia-Wen ; Chang, Hao-Hsiang ; Lee, Long-Teng ; Huang, Kuo-Chin
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-06, Vol.6 (1), p.27034-27034, Article 27034
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ArticlesPeer ReviewedFull Text
Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis
Author / Creator:Yamada, Naoya ; Karasawa, Tadayoshi ; Ito, Junya ; Yamamuro, Daisuke ; Morimoto, Kazushi ; Nakamura, Toshitaka ; Komada, Takanori ; Baatarjav, Chintogtokh ; Saimoto, Yuma ; Jinnouchi, Yuka ; Watanabe, Kazuhisa ; Miura, Kouichi ; Yahagi, Naoya ; Nakagawa, Kiyotaka ; Matsumura, Takayoshi ; Yamada, Ken-ichi ; Ishibashi, Shun ; Sata, Naohiro ; Conrad, Marcus ; Takahashi, Masafumi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-03, Vol.15 (1), p.2195-2195, Article 2195
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ArticlesPeer ReviewedFull Text
Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis
Author / Creator:Lee, Chanbin ; Kim, Jieun ; Han, Jinsol ; Oh, Dayoung ; Kim, Minju ; Jeong, Hayeong ; Kim, Tae-Jin ; Kim, Sang-Woo ; Kim, Jeong Nam ; Seo, Young-Su ; Suzuki, Ayako ; Kim, Jae Ho ; Jung, Youngmi
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-01, Vol.13 (1), p.578-17, Article 578
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ArticlesPeer ReviewedFull Text
Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis
Author / Creator:Yan, Hao ; Wu, Wentong ; Hu, Yuhuai ; Li, Jinjin ; Xu, Jiangxin ; Chen, Xueqin ; Xu, Zhifei ; Yang, Xiaochun ; Yang, Bo ; He, Qiaojun ; Luo, Peihua
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-05, Vol.14 (1), p.2756-2756, Article 2756
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ArticlesPeer ReviewedFull Text
The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury
Author / Creator:Lee, Hakjoo ; Lee, Tae Jin ; Galloway, Chad A. ; Zhi, Wenbo ; Xiao, Wei ; de Mesy Bentley, Karen L. ; Sharma, Ashok ; Teng, Yong ; Sesaki, Hiromi ; Yoon, Yisang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-10, Vol.14 (1), p.6721-6721, Article 6721
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FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC
Author / Creator:Li, Rong ; Yan, Xijing ; Xiao, Cuicui ; Wang, Tingting ; Li, Xuejiao ; Hu, Zhongying ; Liang, Jinliang ; Zhang, Jiebin ; Cai, Jianye ; Sui, Xin ; Liu, Qiuli ; Wu, Manli ; Xiao, Jiaqi ; Chen, Haitian ; Liu, Yasong ; Jiang, Chenhao ; Lv, Guo ; Chen, Guihua ; Zhang, Yingcai ; Yao, Jia ; Zheng, Jun ; Yang, Yang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-06, Vol.15 (1), p.4760-20, Article 4760
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Clinical predictors of recovery of COVID-19 associated-abnormal liver function test 2 months after hospital discharge
Author / Creator:Lu, Justin Y. ; Ho, Scott L. ; Buczek, Alexandra ; Fleysher, Roman ; Hou, Wei ; Chacko, Kristina ; Duong, Tim Q.
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-10, Vol.12 (1), p.17972-17972, Article 17972
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ArticlesPeer ReviewedFull Text
Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability
Author / Creator:Hendriks, Delilah F. G. ; Fredriksson Puigvert, Lisa ; Messner, Simon ; Mortiz, Wolfgang ; Ingelman-Sundberg, Magnus
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2016-10, Vol.6 (1), p.35434, Article 35434
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Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis
Author / Creator:Tian, Panpan ; Yang, Wenwen ; Guo, Xiaowei ; Wang, Tixiao ; Tan, Siyu ; Sun, Renhui ; Xiao, Rong ; Wang, Yuzhen ; Jiao, Deyan ; Xu, Yachen ; Wei, Yanfei ; Wu, Zhuanchang ; Li, Chunyang ; Gao, Lifen ; Ma, Chunhong ; Liang, Xiaohong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-03, Vol.14 (1), p.1710-1710, Article 1710
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The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes
Author / Creator:Xu, Minxuan ; Tan, Jun ; Dong, Wei ; Zou, Benkui ; Teng, Xuepeng ; Zhu, Liancai ; Ge, Chenxu ; Dai, Xianling ; Kuang, Qin ; Zhong, Shaoyu ; Lai, Lili ; Yi, Chao ; Tang, Tingting ; Zhao, Junjie ; Wang, Longyan ; Liu, Jin ; Wei, Hao ; Sun, Yan ; Yang, Qiufeng ; Li, Qiang ; Lou, Deshuai ; Hu, Linfeng ; Liu, Xi ; Kuang, Gang ; Luo, Jing ; Xiong, Mingxin ; Feng, Jing ; Zhang, Chufeng ; Wang, Bochu
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-02, Vol.13 (1), p.1052-1052, Article 1052
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Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage
Author / Creator:Ruz-Maldonado, Inmaculada ; Gonzalez, John T. ; Zhang, Hanming ; Sun, Jonathan ; Bort, Alicia ; Kabir, Inamul ; Kibbey, Richard G. ; Suárez, Yajaira ; Greif, Daniel M. ; Fernández-Hernando, Carlos
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2024-02, Vol.15 (1), p.1247-23, Article 1247
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ArticlesPeer ReviewedFull Text
The alterations in the extracellular matrix composition guide the repair of damaged liver tissue
Author / Creator:Klaas, Mariliis ; Kangur, Triin ; Viil, Janeli ; Mäemets-Allas, Kristina ; Minajeva, Ave ; Vadi, Krista ; Antsov, Mikk ; Lapidus, Natalia ; Järvekülg, Martin ; Jaks, Viljar
Publisher:London: Nature Publishing Group UK
Journal title:SCIENTIFIC REPORTS, 2016-06, Vol.6 (1), p.27398-27398, Article 27398
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Liver regeneration: biological and pathological mechanisms and implications

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Characterization of primary human hepatocyte spheroids as a model system for drug-induced liver injury, liver function and disease

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Spatial Transcriptomics to define transcriptional patterns of zonation and structural components in the mouse liver

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Author Correction: Targeting senescent hepatocytes for treatment of metabolic dysfunction-associated steatotic liver disease and multi-organ dysfunction

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Mettl3-mediated mRNA m6A modification controls postnatal liver development by modulating the transcription factor Hnf4a

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Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis

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Author Correction: p21-activated kinase 4 suppresses fatty acid β-oxidation and ketogenesis by phosphorylating NCoR1

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Mfsd2a+ hepatocytes repopulate the liver during injury and regeneration

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Association of Non-alcoholic Fatty Liver Disease with Metabolic Syndrome Independently of Central Obesity and Insulin Resistance

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Inhibition of 7-dehydrocholesterol reductase prevents hepatic ferroptosis under an active state of sterol synthesis

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Formyl peptide receptor 2 determines sex-specific differences in the progression of nonalcoholic fatty liver disease and steatohepatitis

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Regorafenib inhibits EphA2 phosphorylation and leads to liver damage via the ERK/MDM2/p53 axis

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The mitochondrial fusion protein OPA1 is dispensable in the liver and its absence induces mitohormesis to protect liver from drug-induced injury

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FTO deficiency in older livers exacerbates ferroptosis during ischaemia/reperfusion injury by upregulating ACSL4 and TFRC

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Clinical predictors of recovery of COVID-19 associated-abnormal liver function test 2 months after hospital discharge

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Hepatic 3D spheroid models for the detection and study of compounds with cholestatic liability

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Early life gut microbiota sustains liver-resident natural killer cells maturation via the butyrate-IL-18 axis

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The E3 ubiquitin-protein ligase Trim31 alleviates non-alcoholic fatty liver disease by targeting Rhbdf2 in mouse hepatocytes

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Heterogeneity of hepatocyte dynamics restores liver architecture after chemical, physical or viral damage

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The alterations in the extracellular matrix composition guide the repair of damaged liver tissue

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