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ArticlesPeer ReviewedFull Text
The lung microenvironment: an important regulator of tumour growth and metastasis
Author / Creator:Altorki, Nasser K. ; Markowitz, Geoffrey J. ; Gao, Dingcheng ; Port, Jeffrey L. ; Saxena, Ashish ; Stiles, Brendon ; McGraw, Timothy ; Mittal, Vivek
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2019-01, Vol.19 (1), p.9-31
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Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial
Author / Creator:Altorki, Nasser K, Prof ; McGraw, Timothy E, Prof ; Borczuk, Alain C, Prof ; Saxena, Ashish, MD ; Port, Jeffrey L, Prof ; Stiles, Brendon M, MD ; Lee, Benjamin E, MD ; Sanfilippo, Nicholas J, MD ; Scheff, Ronald J, MD ; Pua, Bradley B, MD ; Gruden, James F, Prof ; Christos, Paul J, PhD ; Spinelli, Cathy, BS ; Gakuria, Joyce, MPH ; Uppal, Manik, MD ; Binder, Bhavneet, MS ; Elemento, Olivier, Prof ; Ballman, Karla V, Prof ; Formenti, Silvia C, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2021-06, Vol.22 (6), p.824-835
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Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer
Author / Creator:Altorki, Nasser ; Wang, Xiaofei ; Kozono, David ; Watt, Colleen ; Landrenau, Rodney ; Wigle, Dennis ; Port, Jeffrey ; Jones, David R. ; Conti, Massimo ; Ashrafi, Ahmad S. ; Liberman, Moishe ; Yasufuku, Kazuhiro ; Yang, Stephen ; Mitchell, John D. ; Pass, Harvey ; Keenan, Robert ; Bauer, Thomas ; Miller, Daniel ; Kohman, Leslie J. ; Stinchcombe, Thomas E. ; Vokes, Everett
Publisher:United States: Massachusetts Medical Society
Journal title:The New England journal of medicine, 2023-02, Vol.388 (6), p.489-498
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Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance
Author / Creator:Fischer, Kari R. ; Durrans, Anna ; Lee, Sharrell ; Sheng, Jianting ; Li, Fuhai ; Wong, Stephen T. C. ; Choi, Hyejin ; El Rayes, Tina ; Ryu, Seongho ; Troeger, Juliane ; Schwabe, Robert F. ; Vahdat, Linda T. ; Altorki, Nasser K. ; Mittal, Vivek ; Gao, Dingcheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2015-11, Vol.527 (7579), p.472-476
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Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring
Author / Creator:Zviran, Asaf ; Schulman, Rafael C. ; Shah, Minita ; Hill, Steven T. K. ; Deochand, Sunil ; Khamnei, Cole C. ; Maloney, Dillon ; Patel, Kristofer ; Liao, Will ; Widman, Adam J. ; Wong, Phillip ; Callahan, Margaret K. ; Ha, Gavin ; Reed, Sarah ; Rotem, Denisse ; Frederick, Dennie ; Sharova, Tatyana ; Miao, Benchun ; Kim, Tommy ; Gydush, Greg ; Rhoades, Justin ; Huang, Kevin Y. ; Omans, Nathaniel D. ; Bolan, Patrick O. ; Lipsky, Andrew H. ; Ang, Chelston ; Malbari, Murtaza ; Spinelli, Catherine F. ; Kazancioglu, Selena ; Runnels, Alexi M. ; Fennessey, Samantha ; Stolte, Christian ; Gaiti, Federico ; Inghirami, Giorgio G. ; Adalsteinsson, Viktor ; Houck-Loomis, Brian ; Ishii, Jennifer ; Wolchok, Jedd D. ; Boland, Genevieve ; Robine, Nicolas ; Altorki, Nasser K. ; Landau, Dan A.
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-07, Vol.26 (7), p.1114-1124
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TOX is a critical regulator of tumour-specific T cell differentiation
Author / Creator:Scott, Andrew C. ; Dündar, Friederike ; Zumbo, Paul ; Chandran, Smita S. ; Klebanoff, Christopher A. ; Shakiba, Mojdeh ; Trivedi, Prerak ; Menocal, Laura ; Appleby, Heather ; Camara, Steven ; Zamarin, Dmitriy ; Walther, Tyler ; Snyder, Alexandra ; Femia, Matthew R. ; Comen, Elizabeth A. ; Wen, Hannah Y. ; Hellmann, Matthew D. ; Anandasabapathy, Niroshana ; Liu, Yong ; Altorki, Nasser K. ; Lauer, Peter ; Levy, Olivier ; Glickman, Michael S. ; Kaye, Jonathan ; Betel, Doron ; Philip, Mary ; Schietinger, Andrea
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-07, Vol.571 (7764), p.270-274
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Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1
Author / Creator:Rayes, Tina El ; Catena, Raúl ; Lee, Sharrell ; Stawowczyk, Marcin ; Joshi, Natasha ; Fischbach, Claudia ; Powell, Charles A. ; Dannenberg, Andrew J. ; Altorki, Nasser K. ; Gao, Dingcheng ; Mittal, Vivek
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-12, Vol.112 (52), p.16000-16005
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ArticlesPeer ReviewedFull Text
Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake
Author / Creator:Beg, Muheeb ; Abdullah, Nazish ; Thowfeik, Fathima Shazna ; Altorki, Nasser K ; McGraw, Timothy E
Publisher:England: eLife Science Publications, Ltd
Journal title:eLife, 2017-06, Vol.6
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The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome
Author / Creator:Remark, Romain ; Becker, Christian ; Gomez, Jorge E ; Damotte, Diane ; Dieu-Nosjean, Marie-Caroline ; Sautès-Fridman, Catherine ; Fridman, Wolf-Herman ; Powell, Charles A ; Altorki, Nasser K ; Merad, Miriam ; Gnjatic, Sacha
Publisher:United States: American Thoracic Society
Journal title:American journal of respiratory and critical care medicine, 2015-02, Vol.191 (4), p.377-390
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ArticlesPeer ReviewedFull Text
Elevated Preoperative Neutrophil:Lymphocyte Ratio as a Predictor of Postoperative Disease Recurrence in Esophageal Cancer
Author / Creator:Sharaiha, Reem Z. ; Halazun, Karim J. ; Mirza, Farooq ; Port, Jeffrey L. ; Lee, Paul C. ; Neugut, Alfred I. ; Altorki, Nasser K. ; Abrams, Julian A.
Publisher:New York: Springer-Verlag
Journal title:Annals of surgical oncology, 2011-11, Vol.18 (12), p.3362-3369
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ArticlesPeer ReviewedFull Text
Molecular Testing for Early Lung Cancer
Author / Creator:Altorki, Nasser K
Publisher:United States: College of American Pathologists
Journal title:Archives of pathology & laboratory medicine (1976), 2018-07, Vol.142 (7), p.794-795
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Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, pha...
Author / Creator:Vansteenkiste, Johan F, Prof Dr ; Cho, Byoung Chul, MD ; Vanakesa, Tonu, MD ; De Pas, Tommaso, MD ; Zielinski, Marcin, Prof ; Kim, Moon Soo, MD ; Jassem, Jacek, Prof ; Yoshimura, Masahiro, MD ; Dahabreh, Jubrail, MD ; Nakayama, Haruhiku, MD ; Havel, Libor, MD ; Kondo, Haruhiko, MD ; Mitsudomi, Tetsuya, Prof ; Zarogoulidis, Konstantinos, Prof ; Gladkov, Oleg A, MD ; Udud, Katalin, MD ; Tada, Hirohito, MD ; Hoffman, Hans, Prof ; Bugge, Anders, MD ; Taylor, Paul, MD ; Gonzalez, Emilio Esteban, Prof ; Liao, Mei Lin, Prof ; He, Jianxing, MD ; Pujol, Jean-Louis, Prof ; Louahed, Jamila, PhD ; Debois, Muriel, MSc ; Brichard, Vincent, MD ; Debruyne, Channa, MD ; Therasse, Patrick, MD ; Altorki, Nasser, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2016-06, Vol.17 (6), p.822-835
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ArticlesPeer ReviewedFull Text
Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer
Author / Creator:Crowley, Michael J. P. ; Bhinder, Bhavneet ; Markowitz, Geoffrey J. ; Martin, Mitchell ; Verma, Akanksha ; Sandoval, Tito A. ; Chae, Chang-Suk ; Yomtoubian, Shira ; Hu, Yang ; Chopra, Sahil ; Tavarez, Diamile A. ; Giovanelli, Paolo ; Gao, Dingcheng ; McGraw, Timothy E. ; Altorki, Nasser K. ; Elemento, Olivier ; Cubillos-Ruiz, Juan R. ; Mittal, Vivek
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-01, Vol.14 (1), p.120-120, Article 120
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Long term survival with thoracoscopic versus open lobectomy: propensity matched comparative analysis using SEER-Medicare database
Author / Creator:Paul, Subroto ; Isaacs, Abby J ; Treasure, Tom ; Altorki, Nasser K ; Sedrakyan, Art
Publisher:England: British Medical Journal Publishing Group
Journal title:BMJ (Online), 2014-10, Vol.349 (oct02 3), p.g5575-g5575
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Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression
Author / Creator:Yoo, Seungyeul ; Sinha, Abhilasha ; Yang, Dawei ; Altorki, Nasser K. ; Tandon, Radhika ; Wang, Wenhui ; Chavez, Deebly ; Lee, Eunjee ; Patel, Ayushi S. ; Sato, Takashi ; Kong, Ranran ; Ding, Bisen ; Schadt, Eric E. ; Watanabe, Hideo ; Massion, Pierre P. ; Borczuk, Alain C. ; Zhu, Jun ; Powell, Charles A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2022-03, Vol.13 (1), p.1592-1592, Article 1592
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Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial
Author / Creator:Altorki, Nasser K. ; Walsh, Zachary H. ; Melms, Johannes C. ; Port, Jeffery L. ; Lee, Benjamin E. ; Nasar, Abu ; Spinelli, Cathy ; Caprio, Lindsay ; Rogava, Meri ; Ho, Patricia ; Christos, Paul J. ; Saxena, Ashish ; Elemento, Olivier ; Bhinder, Bhavneet ; Ager, Casey ; Amin, Amit Dipak ; Sanfilippo, Nicholas J. ; Mittal, Vivek ; Borczuk, Alain C. ; Formenti, Silvia C. ; Izar, Benjamin ; McGraw, Timothy E.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2023-12, Vol.14 (1), p.8435-14, Article 8435
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TGF-β IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer
Author / Creator:Yao, Zhan ; Fenoglio, Silvia ; Gao, Ding Cheng ; Camiolo, Matthew ; Stiles, Brendon ; Lindsted, Trine ; Schlederer, Michaela ; Johns, Chris ; Altorki, Nasser ; Mittal, Vivek ; Kenner, Lukas ; Sordella, Raffaella
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-08, Vol.107 (35), p.15535-15540
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ArticlesPeer ReviewedFull Text
Fischer et al. reply
Author / Creator:Fischer, Kari R. ; Altorki, Nasser K. ; Mittal, Vivek ; Gao, Dingcheng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-07, Vol.547 (7661), p.E5-E6
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ArticlesPeer ReviewedFull Text
Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells
Author / Creator:Letian, Anudari ; Lemma, Eyoel Yemanaberhan ; Cavaliere, Paola ; Dephoure, Noah ; Altorki, Nasser K ; McGraw, Timothy E
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2023-03, Vol.21 (1), p.58-58, Article 58
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p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state
Author / Creator:Senturk, Serif ; Yao, Zhan ; Camiolo, Matthew ; Stiles, Brendon ; Rathod, Trushar ; Walsh, Alice M ; Nemajerova, Alice ; Lazzara, Matthew J ; Altorki, Nasser K ; Krainer, Adrian ; Moll, Ute M ; Lowe, Scott W ; Cartegni, Luca ; Sordella, Raffaella
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (32), p.E3287-E3296
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The lung microenvironment: an important regulator of tumour growth and metastasis

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Neoadjuvant durvalumab with or without stereotactic body radiotherapy in patients with early-stage non-small-cell lung cancer: a single-centre, randomised phase 2 trial

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Lobar or Sublobar Resection for Peripheral Stage IA Non–Small-Cell Lung Cancer

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Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

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Genome-wide cell-free DNA mutational integration enables ultra-sensitive cancer monitoring

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TOX is a critical regulator of tumour-specific T cell differentiation

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Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1

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Distinct Akt phosphorylation states are required for insulin regulated Glut4 and Glut1-mediated glucose uptake

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The non-small cell lung cancer immune contexture. A major determinant of tumor characteristics and patient outcome

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Elevated Preoperative Neutrophil:Lymphocyte Ratio as a Predictor of Postoperative Disease Recurrence in Esophageal Cancer

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Molecular Testing for Early Lung Cancer

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Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, pha...

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Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer

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Long term survival with thoracoscopic versus open lobectomy: propensity matched comparative analysis using SEER-Medicare database

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Integrative network analysis of early-stage lung adenocarcinoma identifies aurora kinase inhibition as interceptor of invasion and progression

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Neoadjuvant durvalumab plus radiation versus durvalumab alone in stages I–III non-small cell lung cancer: survival outcomes and molecular correlates of a randomized phase II trial

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TGF-β IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer

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Fischer et al. reply

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Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells

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p53Ψ is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state

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