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ArticlesPeer ReviewedFull Text
Antimalarial activity of primaquine operates via a two-step biochemical relay
Author / Creator:Camarda, Grazia ; Jirawatcharadech, Piyaporn ; Priestley, Richard S. ; Saif, Ahmed ; March, Sandra ; Wong, Michael H. L. ; Leung, Suet ; Miller, Alex B. ; Baker, David A. ; Alano, Pietro ; Paine, Mark J. I. ; Bhatia, Sangeeta N. ; O’Neill, Paul M. ; Ward, Stephen A. ; Biagini, Giancarlo A.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-07, Vol.10 (1), p.3226-9, Article 3226
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Inflammatory memory sensitizes skin epithelial stem cells to tissue damage
Author / Creator:Naik, Shruti ; Larsen, Samantha B. ; Gomez, Nicholas C. ; Alaverdyan, Kirill ; Sendoel, Ataman ; Yuan, Shaopeng ; Polak, Lisa ; Kulukian, Anita ; Chai, Sophia ; Fuchs, Elaine
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-10, Vol.550 (7677), p.475-480
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Inflammation induces dermal Vγ4⁺γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17–driven responses
Author / Creator:Ramírez-Valle, Francisco ; Gray, Elizabeth E. ; Cyster, Jason G.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2015-06, Vol.112 (26), p.8046-8051
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Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice
Author / Creator:Pantelyushin, Stanislav ; Haak, Stefan ; Ingold, Barbara ; Kulig, Paulina ; Heppner, Frank L ; Navarini, Alexander A ; Becher, Burkhard
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-06, Vol.122 (6), p.2252-2256
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IL-12 protects from psoriasiform skin inflammation
Author / Creator:Kulig, Paulina ; Musiol, Stephanie ; Freiberger, Sandra Nicole ; Schreiner, Bettina ; Gyülveszi, Gabor ; Russo, Giancarlo ; Pantelyushin, Stanislav ; Kishihara, Kenji ; Alessandrini, Francesca ; Kündig, Thomas ; Sallusto, Federica ; Hofbauer, Günther F.L. ; Haak, Stefan ; Becher, Burkhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-11, Vol.7 (1), p.13466-13466, Article 13466
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Ferrocene-Based Compounds with Antimalaria/Anticancer Activity
Author / Creator:Peter, Sijongesonke ; Aderibigbe, Blessing Atim
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2019-10, Vol.24 (19), p.3604
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ArticlesPeer ReviewedFull Text
Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation
Author / Creator:Singh, Tej Pratap ; Zhang, Howard H. ; Borek, Izabela ; Wolf, Peter ; Hedrick, Michael N. ; Singh, Satya P. ; Kelsall, Brian L. ; Clausen, Bjorn E. ; Farber, Joshua M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-12, Vol.7 (1), p.13581-13581, Article 13581
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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy
Author / Creator:Huber, Kilian V. M. ; Salah, Eidarus ; Radic, Branka ; Gridling, Manuela ; Elkins, Jonathan M. ; Stukalov, Alexey ; Jemth, Ann-Sofie ; Göktürk, Camilla ; Sanjiv, Kumar ; Strömberg, Kia ; Pham, Therese ; Berglund, Ulrika Warpman ; Colinge, Jacques ; Bennett, Keiryn L. ; Loizou, Joanna I. ; Helleday, Thomas ; Knapp, Stefan ; Superti-Furga, Giulio
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2014-04, Vol.508 (7495), p.222-227
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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes
Author / Creator:Rodriguez, Raphaël ; Miller, Kyle M ; Forment, Josep V ; Bradshaw, Charles R ; Nikan, Mehran ; Britton, Sébastien ; Oelschlaegel, Tobias ; Xhemalce, Blerta ; Balasubramanian, Shankar ; Jackson, Stephen P
Publisher:New York: Nature Publishing Group US
Journal title:Nature chemical biology, 2012-03, Vol.8 (3), p.301-310
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ArticlesPeer ReviewedFull Text
Actin dynamics counteract membrane tension during clathrin-mediated endocytosis
Author / Creator:Boulant, Steeve ; Kural, Comert ; Zeeh, Jean-Christophe ; Ubelmann, Florent ; Kirchhausen, Tomas
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2011-09, Vol.13 (9), p.1124-1131
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ArticlesPeer ReviewedFull Text
Targeting quiescent leukemic stem cells using second generation autophagy inhibitors
Author / Creator:Baquero, Pablo ; Dawson, Amy ; Mukhopadhyay, Arunima ; Kuntz, Elodie M. ; Mitchell, Rebecca ; Olivares, Orianne ; Ianniciello, Angela ; Scott, Mary T. ; Dunn, Karen ; Nicastri, Michael C. ; Winkler, Jeffrey D. ; Michie, Alison M. ; Ryan, Kevin M. ; Halsey, Christina ; Gottlieb, Eyal ; Keaney, Erin P. ; Murphy, Leon O. ; Amaravadi, Ravi K. ; Holyoake, Tessa L. ; Helgason, G. Vignir
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2019-04, Vol.33 (4), p.981-994
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Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis
Author / Creator:Swindell, William R ; Michaels, Kellie A ; Sutter, Andrew J ; Diaconu, Doina ; Fritz, Yi ; Xing, Xianying ; Sarkar, Mrinal K ; Liang, Yun ; Tsoi, Alex ; Gudjonsson, Johann E ; Ward, Nicole L
Publisher:England: BioMed Central
Journal title:Genome medicine, 2017-03, Vol.9 (1), p.24-24, Article 24
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ArticlesPeer ReviewedFull Text
Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA
Author / Creator:Lista, María José ; Martins, Rodrigo Prado ; Billant, Olivier ; Contesse, Marie-Astrid ; Findakly, Sarah ; Pochard, Pierre ; Daskalogianni, Chrysoula ; Beauvineau, Claire ; Guetta, Corinne ; Jamin, Christophe ; Teulade-Fichou, Marie-Paule ; Fåhraeus, Robin ; Voisset, Cécile ; Blondel, Marc
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-07, Vol.8 (1), p.16043-27, Article 16043
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ArticlesPeer ReviewedFull Text
IL-23 from Langerhans Cells Is Required for the Development of Imiquimod-Induced Psoriasis-Like Dermatitis by Induction of IL-17A-Producing γδ T Cells
Author / Creator:Yoshiki, Ryutaro ; Kabashima, Kenji ; Honda, Tetsuya ; Nakamizo, Satoshi ; Sawada, Yu ; Sugita, Kazunari ; Yoshioka, Haruna ; Ohmori, Shun ; Malissen, Bernard ; Tokura, Yoshiki ; Nakamura, Motonobu
Publisher:United States: Elsevier Inc
Journal title:Journal of investigative dermatology, 2014-07, Vol.134 (7), p.1912-1921
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ArticlesPeer ReviewedFull Text
Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency
Author / Creator:McAfee, Quentin ; Zhang, Zhihui ; Samanta, Arabinda ; Levi, Samuel M ; Ma, Xiao-Hong ; Piao, Shengfu ; Lynch, John P ; Uehara, Takeshi ; Sepulveda, Antonia R ; Davis, Lisa E ; Winkler, Jeffrey D ; Amaravadi, Ravi K
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-05, Vol.109 (21), p.8253-8258
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ArticlesPeer ReviewedFull Text
CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation
Author / Creator:De Rubeis, Silvia ; Pasciuto, Emanuela ; Li, Ka Wan ; Fernández, Esperanza ; Di Marino, Daniele ; Buzzi, Andrea ; Ostroff, Linnaea E. ; Klann, Eric ; Zwartkruis, Fried J.T. ; Komiyama, Noboru H. ; Grant, Seth G.N. ; Poujol, Christel ; Choquet, Daniel ; Achsel, Tilmann ; Posthuma, Danielle ; Smit, August B. ; Bagni, Claudia
Publisher:United States: Elsevier Inc
Journal title:Neuron (Cambridge, Mass.), 2013-09, Vol.79 (6), p.1169-1182
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ArticlesPeer ReviewedFull Text
Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response
Author / Creator:Zákostelská, Zuzana ; Málková, Jana ; Klimešová, Klára ; Rossmann, Pavel ; Hornová, Michaela ; Novosádová, Iva ; Stehlíková, Zuzana ; Kostovčík, Martin ; Hudcovic, Tomáš ; Štepánková, Renata ; Jůzlová, Kateřina ; Hercogová, Jana ; Tlaskalová-Hogenová, Helena ; Kverka, Miloslav
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-07, Vol.11 (7), p.e0159539-e0159539
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ArticlesPeer ReviewedFull Text
P2X7 receptor antagonism by AZ10606120 significantly reduced in vitro tumour growth in human glioblastoma
Author / Creator:Kan, Liyen K. ; Drill, Matthew ; Jayakrishnan, Padmakrishnan C. ; Sequeira, Richard P. ; Galea, Emily ; Todaro, Marian ; Sanfilippo, Paul G. ; Hunn, Martin ; Williams, David A. ; O’Brien, Terence J. ; Drummond, Katharine J. ; Monif, Mastura
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2023-05, Vol.13 (1), p.8435-8435, Article 8435
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Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells
Author / Creator:Drobits, Barbara ; Holcmann, Martin ; Amberg, Nicole ; Swiecki, Melissa ; Grundtner, Roland ; Hammer, Martina ; Colonna, Marco ; Sibilia, Maria
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2012-02, Vol.122 (2), p.575-585
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Curcumin inhibits imiquimod-induced psoriasis-like inflammation by inhibiting IL-1beta and IL-6 production in mice
Author / Creator:Sun, Jun ; Zhao, Yi ; Hu, Jinhong
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e67078
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Antimalarial activity of primaquine operates via a two-step biochemical relay

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Inflammatory memory sensitizes skin epithelial stem cells to tissue damage

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Inflammation induces dermal Vγ4⁺γδT17 memory-like cells that travel to distant skin and accelerate secondary IL-17–driven responses

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Rorγt+ innate lymphocytes and γδ T cells initiate psoriasiform plaque formation in mice

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IL-12 protects from psoriasiform skin inflammation

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Ferrocene-Based Compounds with Antimalaria/Anticancer Activity

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Monocyte-derived inflammatory Langerhans cells and dermal dendritic cells mediate psoriasis-like inflammation

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Stereospecific targeting of MTH1 by (S)-crizotinib as an anticancer strategy

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Small-molecule–induced DNA damage identifies alternative DNA structures in human genes

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Actin dynamics counteract membrane tension during clathrin-mediated endocytosis

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Targeting quiescent leukemic stem cells using second generation autophagy inhibitors

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Imiquimod has strain-dependent effects in mice and does not uniquely model human psoriasis

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Nucleolin directly mediates Epstein-Barr virus immune evasion through binding to G-quadruplexes of EBNA1 mRNA

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IL-23 from Langerhans Cells Is Required for the Development of Imiquimod-Induced Psoriasis-Like Dermatitis by Induction of IL-17A-Producing γδ T Cells

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Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

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CYFIP1 Coordinates mRNA Translation and Cytoskeleton Remodeling to Ensure Proper Dendritic Spine Formation

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Intestinal Microbiota Promotes Psoriasis-Like Skin Inflammation by Enhancing Th17 Response

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P2X7 receptor antagonism by AZ10606120 significantly reduced in vitro tumour growth in human glioblastoma

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Imiquimod clears tumors in mice independent of adaptive immunity by converting pDCs into tumor-killing effector cells

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Curcumin inhibits imiquimod-induced psoriasis-like inflammation by inhibiting IL-1beta and IL-6 production in mice

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