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Recognition of the amyloid precursor protein by human γ-secretase
Author / Creator:Zhou, Rui ; Yang, Guanghui ; Guo, Xuefei ; Zhou, Qiang ; Lei, Jianlin ; Shi, Yigong
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2019-02, Vol.363 (6428), p.708-708
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Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains
Author / Creator:Vaillant-Beuchot, Loan ; Mary, Arnaud ; Pardossi-Piquard, Raphaëlle ; Bourgeois, Alexandre ; Lauritzen, Inger ; Eysert, Fanny ; Kinoshita, Paula Fernanda ; Cazareth, Julie ; Badot, Céline ; Fragaki, Konstantina ; Bussiere, Renaud ; Martin, Cécile ; Mary, Rosanna ; Bauer, Charlotte ; Pagnotta, Sophie ; Paquis-Flucklinger, Véronique ; Buée-Scherrer, Valérie ; Buée, Luc ; Lacas-Gervais, Sandra ; Checler, Frédéric ; Chami, Mounia
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2021-01, Vol.141 (1), p.39-65
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ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons
Author / Creator:Kuhn, Peer-Hendrik ; Wang, Huanhuan ; Dislich, Bastian ; Colombo, Alessio ; Zeitschel, Ulrike ; Ellwart, Joachim W ; Kremmer, Elisabeth ; Roßner, Steffen ; Lichtenthaler, Stefan F
Publisher:Chichester, UK: John Wiley & Sons, Ltd
Journal title:The EMBO journal, 2010-09, Vol.29 (17), p.3020-3032
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Amyloid Precursor Protein and Alzheimer’s Disease
Author / Creator:Orobets, Kseniia S ; Karamyshev, Andrey L
Publisher:Basel: MDPI AG
Journal title:International journal of molecular sciences, 2023-10, Vol.24 (19), p.14794
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Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease
Author / Creator:Zhang, Zhentao ; Song, Mingke ; Liu, Xia ; Su Kang, Seong ; Duong, Duc M. ; Seyfried, Nicholas T. ; Cao, Xuebing ; Cheng, Liming ; Sun, Yi E. ; Ping Yu, Shan ; Jia, Jianping ; Levey, Allan I. ; Ye, Keqiang
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2015-11, Vol.6 (1), p.8762-8762, Article 8762
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Brain Ischemia Activates β- and γ-Secretase Cleavage of Amyloid Precursor Protein: Significance in Sporadic Alzheimer’s Disease
Author / Creator:Pluta, Ryszard ; Furmaga-Jabłońska, Wanda ; Maciejewski, Ryszard ; Ułamek-Kozioł, Marzena ; Jabłoński, Mirosław
Publisher:New York: Humana Press Inc
Journal title:Molecular neurobiology, 2013-02, Vol.47 (1), p.425-434
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Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention
Author / Creator:Tsatsanis, Andrew ; Wong, Bruce X. ; Gunn, Adam P. ; Ayton, Scott ; Bush, Ashley I. ; Devos, David ; Duce, James A.
Publisher:London: Nature Publishing Group UK
Journal title:Molecular psychiatry, 2020-09, Vol.25 (9), p.1958-1966
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Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer's Disease Mouse Model
Author / Creator:Guo, Chuang ; Yang, Zhao-Hui ; Zhang, Shuai ; Chai, Rui ; Xue, Han ; Zhang, Yan-Hui ; Li, Jia-Yi ; Wang, Zhan-You
Publisher:England: Nature Publishing Group
Journal title:Neuropsychopharmacology (New York, N.Y.), 2017-12, Vol.42 (13), p.2504-2515
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A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models
Author / Creator:Song, Ju‐Xian ; Malampati, Sandeep ; Zeng, Yu ; Durairajan, Siva Sundara Kumar ; Yang, Chuan‐Bin ; Tong, Benjamin Chun‐Kit ; Iyaswamy, Ashok ; Shang, Wen‐Bin ; Sreenivasmurthy, Sravan Gopalkrishnashetty ; Zhu, Zhou ; Cheung, King‐Ho ; Lu, Jia‐Hong ; Tang, Chunzhi ; Xu, Nenggui ; Li, Min
Publisher:England: John Wiley & Sons, Inc
Journal title:Aging cell, 2020-02, Vol.19 (2), p.e13069-n/a
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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration
Author / Creator:Xu, Wei ; Weissmiller, April M ; White, 2nd, Joseph A ; Fang, Fang ; Wang, Xinyi ; Wu, Yiwen ; Pearn, Matthew L ; Zhao, Xiaobei ; Sawa, Mariko ; Chen, Shengdi ; Gunawardena, Shermali ; Ding, Jianqing ; Mobley, William C ; Wu, Chengbiao
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2016-05, Vol.126 (5), p.1815-1833
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Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network
Author / Creator:Choy, Regina Wai-Yan ; Cheng, Zhiliang ; Schekman, Randy
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2012-07, Vol.109 (30), p.E2077-E2082
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Not just amyloid: physiological functions of the amyloid precursor protein family
Author / Creator:Müller, Ulrike C. ; Deller, Thomas ; Korte, Martin
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Neuroscience, 2017-05, Vol.18 (5), p.281-298
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Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid β-peptides in human cerebrospinal fluid
Author / Creator:Halim, Adnan ; Brinkmalm, Gunnar ; Rüetschi, Ulla ; Westman-Brinkmalm, Ann ; Portelius, Erik ; Zetterberg, Henrik ; Blennow, Kaj ; Larson, Göran ; Nilsson, Jonas
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2011-07, Vol.108 (29), p.11848-11853
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Deciphering the neuroprotective and neurogenic potential of soluble amyloid precursor protein alpha (sAPPα)
Author / Creator:Dar, Nawab John ; Glazner, Gordon W.
Publisher:Cham: Springer International Publishing
Journal title:Cellular and molecular life sciences : CMLS, 2020-06, Vol.77 (12), p.2315-2330
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The amyloid precursor protein: a converging point in Alzheimer’s disease
Author / Creator:Delport, Alexandré ; Hewer, Raymond
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2022-07, Vol.59 (7), p.4501-4516
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Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein
Author / Creator:Cho, Yoon Young ; Kwon, Oh-Hoon ; Park, Myoung Kyu ; Kim, Tae-Wan ; Chung, Sungkwon
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-01, Vol.14 (1), p.e0210535-e0210535
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Secreted amyloid precursor protein β and secreted amyloid precursor protein α induce axon outgrowth in vitro through Egr1 signaling pathway
Author / Creator:Chasseigneaux, Stéphanie ; Dinc, Levent ; Rose, Christiane ; Chabret, Claude ; Coulpier, Fanny ; Topilko, Piotr ; Mauger, Gweltas ; Allinquant, Bernadette
Publisher:United States: Public Library of Science
Journal title:PloS one, 2011-01, Vol.6 (1), p.e16301
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Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer’s Disease (AD) and Age-Related Macular Degeneration (AMD)
Author / Creator:Zhao, Yuhai ; Bhattacharjee, Surjyadipta ; Jones, Brandon M. ; Hill, James M. ; Clement, Christian ; Sambamurti, Kumar ; Dua, Prerna ; Lukiw, Walter J.
Publisher:New York: Springer US
Journal title:Molecular neurobiology, 2015-08, Vol.52 (1), p.533-544
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Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity
Author / Creator:Hick, Meike ; Herrmann, Ulrike ; Weyer, Sascha W. ; Mallm, Jan-Philipp ; Tschäpe, Jakob-Andreas ; Borgers, Marianne ; Mercken, Marc ; Roth, Fabian C. ; Draguhn, Andreas ; Slomianka, Lutz ; Wolfer, David P. ; Korte, Martin ; Müller, Ulrike C.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Acta neuropathologica, 2015-01, Vol.129 (1), p.21-37
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Lumbar Cerebrospinal Fluid Biomarkers of Posthemorrhagic Hydrocephalus of Prematurity: Amyloid Precursor Protein, Soluble Amyloid Precursor Protein α, and L1 Cell Adhesion Molecule
Author / Creator:Morales, Diego M. ; Silver, Shawgi A. ; Morgan, Clinton D. ; Mercer, Deanna ; Inder, Terri E. ; Holtzman, David M. ; Wallendorf, Michael J. ; Rao, Rakesh ; McAllister, James P. ; Limbrick, David D.
Publisher:United States: Oxford University Press
Journal title:Neurosurgery, 2017-01, Vol.80 (1), p.82-90
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Recognition of the amyloid precursor protein by human γ-secretase

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Accumulation of amyloid precursor protein C-terminal fragments triggers mitochondrial structure, function, and mitophagy defects in Alzheimer’s disease models and human brains

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ADAM10 is the physiologically relevant, constitutive α-secretase of the amyloid precursor protein in primary neurons

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Amyloid Precursor Protein and Alzheimer’s Disease

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Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease

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Brain Ischemia Activates β- and γ-Secretase Cleavage of Amyloid Precursor Protein: Significance in Sporadic Alzheimer’s Disease

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Amyloidogenic processing of Alzheimer’s disease β-amyloid precursor protein induces cellular iron retention

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Intranasal Lactoferrin Enhances α-Secretase-Dependent Amyloid Precursor Protein Processing via the ERK1/2-CREB and HIF-1α Pathways in an Alzheimer's Disease Mouse Model

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A small molecule transcription factor EB activator ameliorates beta‐amyloid precursor protein and Tau pathology in Alzheimer's disease models

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Amyloid precursor protein-mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

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Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans-Golgi network

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Not just amyloid: physiological functions of the amyloid precursor protein family

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Site-specific characterization of threonine, serine, and tyrosine glycosylations of amyloid precursor protein/amyloid β-peptides in human cerebrospinal fluid

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Deciphering the neuroprotective and neurogenic potential of soluble amyloid precursor protein alpha (sAPPα)

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The amyloid precursor protein: a converging point in Alzheimer’s disease

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Elevated cellular cholesterol in Familial Alzheimer's presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein

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Secreted amyloid precursor protein β and secreted amyloid precursor protein α induce axon outgrowth in vitro through Egr1 signaling pathway

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Beta-Amyloid Precursor Protein (βAPP) Processing in Alzheimer’s Disease (AD) and Age-Related Macular Degeneration (AMD)

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Acute function of secreted amyloid precursor protein fragment APPsα in synaptic plasticity

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Lumbar Cerebrospinal Fluid Biomarkers of Posthemorrhagic Hydrocephalus of Prematurity: Amyloid Precursor Protein, Soluble Amyloid Precursor Protein α, and L1 Cell Adhesion Molecule

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