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ArticlesPeer ReviewedFull Text
Orthosteric and allosteric action of the C5a receptor antagonists
Author / Creator:Liu, Heng ; Kim, Hee Ryung ; Deepak, R. N. V. Krishna ; Wang, Lei ; Chung, Ka Young ; Fan, Hao ; Wei, Zhiyi ; Zhang, Cheng
Publisher:New York: Nature Publishing Group US
Journal title:Nature structural & molecular biology, 2018-06, Vol.25 (6), p.472-481
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BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial
Author / Creator:Bockorny, Bruno ; Semenisty, Valerya ; Macarulla, Teresa ; Borazanci, Erkut ; Wolpin, Brian M. ; Stemmer, Salomon M. ; Golan, Talia ; Geva, Ravit ; Borad, Mitesh J. ; Pedersen, Katrina S. ; Park, Joon Oh ; Ramirez, Robert A. ; Abad, David G. ; Feliu, Jaime ; Muñoz, Andres ; Ponz-Sarvise, Mariano ; Peled, Amnon ; Lustig, Tzipora M. ; Bohana-Kashtan, Osnat ; Shaw, Stephen M. ; Sorani, Ella ; Chaney, Marya ; Kadosh, Shaul ; Vainstein Haras, Abi ; Von Hoff, Daniel D. ; Hidalgo, Manuel
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2020-06, Vol.26 (6), p.878-885
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The TLR4 antagonist Eritoran protects mice from lethal influenza infection
Author / Creator:Shirey, Kari Ann ; Lai, Wendy ; Scott, Alison J. ; Lipsky, Michael ; Mistry, Pragnesh ; Pletneva, Lioubov M. ; Karp, Christopher L. ; McAlees, Jaclyn ; Gioannini, Theresa L. ; Weiss, Jerrold ; Chen, Wilbur H. ; Ernst, Robert K. ; Rossignol, Daniel P. ; Gusovsky, Fabian ; Blanco, Jorge C. G. ; Vogel, Stefanie N.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-05, Vol.497 (7450), p.498-502
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BCL-2 family antagonists for cancer therapy
Author / Creator:Lessene, Guillaume ; Czabotar, Peter E. ; Colman, Peter M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2008-12, Vol.7 (12), p.989-1000
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Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist
Author / Creator:Spaulding, Caitlin N. ; Klein, Roger D. ; Ruer, Ségolène ; Kau, Andrew L. ; Schreiber, Henry L. ; Cusumano, Zachary T. ; Dodson, Karen W. ; Pinkner, Jerome S. ; Fremont, Daved H. ; Janetka, James W. ; Remaut, Han ; Gordon, Jeffrey I. ; Hultgren, Scott J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2017-06, Vol.546 (7659), p.528-532
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Structural basis of species-selective antagonist binding to the succinate receptor
Author / Creator:Haffke, Matthias ; Fehlmann, Dominique ; Rummel, Gabriele ; Boivineau, Jacques ; Duckely, Myriam ; Gommermann, Nina ; Cotesta, Simona ; Sirockin, Finton ; Freuler, Felix ; Littlewood-Evans, Amanda ; Kaupmann, Klemens ; Jaakola, Veli-Pekka
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2019-10, Vol.574 (7779), p.581-585
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CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers
Author / Creator:Burger, J A ; Peled, A
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2009-01, Vol.23 (1), p.43-52
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Retinoic acid receptor antagonists for male contraception: current status
Author / Creator:Al Noman, Md Abdullah ; Kyzer, Jillian L ; Chung, Sanny S. W ; Wolgemuth, Debra J ; Georg, Gunda I
Publisher:Cary: Society for the Study of Reproduction
Journal title:Biology of reproduction, 2020-08, Vol.103 (2), p.390-399
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A strategy to design protein-based antagonists against type I cytokine receptors
Author / Creator:Ullrich, Timo ; Klimenkova, Olga ; Pollmann, Christoph ; Lasram, Asma ; Hatskovska, Valeriia ; Maksymenko, Kateryna ; Milijaš-Jotić, Matej ; Schenk, Lukas ; Lengerke, Claudia ; Hartmann, Marcus D. ; Piehler, Jacob ; Skokowa, Julia ; ElGamacy, Mohammad
Publisher:United States: Public Library of Science
Journal title:PLoS biology, 2024-11, Vol.22 (11), p.e3002883
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ArticlesPeer ReviewedFull Text
Chemokine receptor antagonists: overcoming developmental hurdles
Author / Creator:Horuk, Richard
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2009-01, Vol.8 (1), p.23-33
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Exploring the Therapeutic Potential of N-Methyl-D-Aspartate Receptor Antagonists in Neuropathic Pain Management
Author / Creator:Pușcașu, Ciprian ; Chiriță, Cornel ; Negreș, Simona ; Blebea, Nicoleta Mirela
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-10, Vol.25 (20), p.11111
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ArticlesPeer ReviewedFull Text
An androgen receptor N-terminal domain antagonist for treating prostate cancer
Author / Creator:Myung, Jae-Kyung ; Banuelos, Carmen A. ; Fernandez, Javier Garcia ; Mawji, Nasrin R. ; Wang, Jun ; Tien, Amy H. ; Yang, Yu Chi ; Tavakoli, Iran ; Haile, Simon ; Watt, Kate ; McEwan, Iain J. ; Plymate, Stephen ; Andersen, Raymond J. ; Sadar, Marianne D.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2013-07, Vol.123 (7), p.2948-2960
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ArticlesPeer ReviewedFull Text
Characterization of a CXCR4 antagonist TIQ-15 with dual tropic HIV entry inhibition properties
Author / Creator:Zhou, Zheng ; Guo, Jia ; Hetrick, Brian ; Tiwari, Sameer ; Haikerwal, Amrita ; Han, Yang ; Bond, Vincent C. ; Huang, Ming B. ; Mankowski, Marie K. ; Snyder, Beth A. ; Hogan, Priscilla A. ; Sharma, Savita K. ; Liotta, Dennis C. ; Reid, Terry-Elinor ; Wilson, Lawrence J. ; Wu, Yuntao
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-08, Vol.20 (8), p.e1012448
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Effort-related effects of chronic administration of the DA D.sub.2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonis...
Author / Creator:Rotolo, Renee A ; Ecevitoglu, Alev ; Presby, Rose E ; Lindgren, Hanna ; Mombereau, Cedric ; Nicholas, Cyrene ; Moore, Alana ; Edelstein, Gayle A ; Correa, Merce ; Salamone, John D
Publisher:Springer
Journal title:Psychopharmacology, 2023-10, Vol.240 (10), p.2173
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NHD2-15, a novel antagonist of Growth Factor Receptor-Bound Protein-2
Author / Creator:Lewis, Tina R ; Smith, Jesse ; Griffin, Kallie ; Aguiar, Stephanie ; Rueb, Kristen F ; Holmberg-Douglas, Natalie ; Sampson, Ellen M ; Tomasetti, Skylar ; Rodriguez, Sofia ; Stachura, David L ; Arpin, Carolynn C ; Buday, Laszlo
Publisher:Public Library of Science
Journal title:PloS one, 2020-08, Vol.15 (8), p.e0236839
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A screened PirB antagonist peptide antagonizes A[beta].sub.42-mediated inhibition of neurite outgrowth in vitro
Author / Creator:Zhang, Zheng ; Wang, Zijian ; Ling, Zhipeng ; Li, Yu ; Pan, Junping ; Gao, Qin ; Zhang, Jichun ; Yan, Li ; Zhang, Zhidong ; Li, Junliang ; Xiao, Fei
Publisher:Springer
Journal title:Applied microbiology and biotechnology, 2021-06, Vol.105 (11), p.4649
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Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype
Author / Creator:Schurgers, Leon J. ; Joosen, Ivo A. ; Laufer, Eduard M. ; Chatrou, Martijn L. L. ; Herfs, Marjolein ; Winkens, Mark H. M. ; Westenfeld, Ralf ; Veulemans, Verena ; Krueger, Thilo ; Shanahan, Catherine M. ; Jahnen-Dechent, Willi ; Biessen, Erik ; Narula, Jagat ; Vermeer, Cees ; Hofstra, Leonard ; Reutelingsperger, Chris P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-08, Vol.7 (8), p.e43229
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Structure of the δ-opioid receptor bound to naltrindole
Author / Creator:Granier, Sébastien ; Manglik, Aashish ; Kruse, Andrew C. ; Kobilka, Tong Sun ; Thian, Foon Sun ; Weis, William I. ; Kobilka, Brian K.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-05, Vol.485 (7398), p.400-404
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Serotonin 2C receptor antagonists induce fast-onset antidepressant effects
Author / Creator:Opal, M. D. ; Klenotich, S. C. ; Morais, M. ; Bessa, J. ; Winkle, J. ; Doukas, D. ; Kay, L. J. ; Sousa, Nuno ; Dulawa, S. M.
Publisher:London: Springer
Journal title:Molecular psychiatry, 2014-10, Vol.19 (10), p.1106-1114
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A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma
Author / Creator:Krishnan, Anitha ; Kocab, Andrew J. ; Zacks, David N. ; Marshak-Rothstein, Ann ; Gregory-Ksander, Meredith
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2019-09, Vol.16 (1), p.184-184, Article 184
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Showing 1 to 20 of 41,611 results

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Orthosteric and allosteric action of the C5a receptor antagonists

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BL-8040, a CXCR4 antagonist, in combination with pembrolizumab and chemotherapy for pancreatic cancer: the COMBAT trial

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The TLR4 antagonist Eritoran protects mice from lethal influenza infection

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BCL-2 family antagonists for cancer therapy

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Selective depletion of uropathogenic E. coli from the gut by a FimH antagonist

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Structural basis of species-selective antagonist binding to the succinate receptor

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CXCR4 antagonists: targeting the microenvironment in leukemia and other cancers

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Retinoic acid receptor antagonists for male contraception: current status

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A strategy to design protein-based antagonists against type I cytokine receptors

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Chemokine receptor antagonists: overcoming developmental hurdles

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Exploring the Therapeutic Potential of N-Methyl-D-Aspartate Receptor Antagonists in Neuropathic Pain Management

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An androgen receptor N-terminal domain antagonist for treating prostate cancer

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Characterization of a CXCR4 antagonist TIQ-15 with dual tropic HIV entry inhibition properties

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Effort-related effects of chronic administration of the DA D.sub.2 receptor antagonist haloperidol via subcutaneous programmable minipumps: Reversal by co-administration of the adenosine A2A antagonis...

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NHD2-15, a novel antagonist of Growth Factor Receptor-Bound Protein-2

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A screened PirB antagonist peptide antagonizes A[beta].sub.42-mediated inhibition of neurite outgrowth in vitro

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Vitamin K-Antagonists Accelerate Atherosclerotic Calcification and Induce a Vulnerable Plaque Phenotype

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Structure of the δ-opioid receptor bound to naltrindole

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Serotonin 2C receptor antagonists induce fast-onset antidepressant effects

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A small peptide antagonist of the Fas receptor inhibits neuroinflammation and prevents axon degeneration and retinal ganglion cell death in an inducible mouse model of glaucoma

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