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Billiar, Timothy R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BAY-BUP, 2022, p.1037-1037
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Billiar, Timothy R
Journal title:American Men & Women of Science : A Biographical Directory of Today’s Leaders in Physical, Biological and Related Sciences: BEA-BUD, 2021, p.1029-1029
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ArticlesPeer ReviewedFull Text
Inflammasome and autophagy regulation - a two-way street
Author / Creator:Sun, Qian ; Fan, Jie ; Billiar, Timothy R ; Scott, Melanie J
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2017-01, Vol.23 (1), p.188-195
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PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
Author / Creator:Xie, Min ; Yu, Yan ; Kang, Rui ; Zhu, Shan ; Yang, Liangchun ; Zeng, Ling ; Sun, Xiaofang ; Yang, Minghua ; Billiar, Timothy R. ; Wang, Haichao ; Cao, Lizhi ; Jiang, Jianxin ; Tang, Daolin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2016-10, Vol.7 (1), p.13280-13280, Article 13280
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PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis
Author / Creator:Yang, Liangchun ; Xie, Min ; Yang, Minghua ; Yu, Yan ; Zhu, Shan ; Hou, Wen ; Kang, Rui ; Lotze, Michael T. ; Billiar, Timothy R. ; Wang, Haichao ; Cao, Lizhi ; Tang, Daolin
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2014-07, Vol.5 (1), p.4436-4436, Article 4436
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iNOS promotes CD24⁺CD133⁺ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway
Author / Creator:Wang, Ronghua ; Li, Yawen ; Tsung, Allan ; Huang, Hai ; Du, Qiang ; Yang, Muqing ; Deng, Meihong ; Xiong, Si ; Wang, Xiju ; Zhang, Liyong ; Geller, David A. ; Cheng, Bin ; Billiar, Timothy R.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (43), p.E10127-E10136
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IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model
Author / Creator:Xu, Jing ; Guardado, Jesse ; Hoffman, Rosemary ; Xu, Hui ; Namas, Rami ; Vodovotz, Yoram ; Xu, Li ; Ramadan, Mostafa ; Brown, Joshua ; Turnquist, Heth R ; Billiar, Timothy R
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2017-07, Vol.14 (7), p.e1002365
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ArticlesPeer ReviewedFull Text
Time for trauma immunology
Author / Creator:Billiar, Timothy R ; Vodovotz, Yoram
Publisher:United States: Public Library of Science
Journal title:PLoS medicine, 2017-07, Vol.14 (7), p.e1002342-e1002342
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Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer
Author / Creator:Kang, Rui ; Xie, Yangchun ; Zhang, Qiuhong ; Hou, Wen ; Jiang, Qingping ; Zhu, Shan ; Liu, Jinbao ; Zeng, Dexing ; Wang, Haichao ; Bartlett, David L ; Billiar, Timothy R ; Zeh, Herbert J ; Lotze, Michael T ; Tang, Daolin
Publisher:London: Nature Publishing Group UK
Journal title:Cell research, 2017-07, Vol.27 (7), p.916-932
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ArticlesPeer ReviewedFull Text
Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation
Author / Creator:Zhu, Xiaorong ; Messer, Jeannette S ; Wang, Yunwei ; Lin, Fanfei ; Cham, Candace M ; Chang, Jonathan ; Billiar, Timothy R ; Lotze, Michael T ; Boone, David L ; Chang, Eugene B
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-03, Vol.125 (3), p.1098-1110
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Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis
Author / Creator:Yan, Zhengzheng ; Luo, Haihua ; Xie, Bingyao ; Tian, Tian ; Li, Shan ; Chen, Zhixia ; Liu, Jinghua ; Zhao, Xuwen ; Zhang, Liyong ; Deng, Yongqiang ; Billiar, Timothy R. ; Jiang, Yong
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2021-01, Vol.12 (1), p.308-14, Article 308
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ArticlesPeer ReviewedFull Text
HMGB1 released from nociceptors mediates inflammation
Author / Creator:Yang, Huan ; Zeng, Qiong ; Silverman, Harold A. ; Gunasekaran, Manojkumar ; George, Sam J. ; Devarajan, Alex ; Addorisio, Meghan E. ; Li, Jianhua ; Tsaava, Téa ; Shah, Vivek ; Billiar, Timothy R. ; Wang, Haichao ; Brines, Michael ; Andersson, Ulf ; Pavlov, Valentin A. ; Chang, Eric H. ; Chavan, Sangeeta S. ; Tracey, Kevin J.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2021-08, Vol.118 (33), p.1-9
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ArticlesPeer ReviewedFull Text
Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1-αvβ5 integrin pathway in TLR4-mediated inflammation and injury
Author / Creator:Ding, Xibing ; Tong, Yao ; Jin, Shuqing ; Chen, Zhixia ; Li, Tunliang ; Billiar, Timothy R ; Pitt, Bruce R ; Li, Quan ; Zhang, Li-Ming
Publisher:England: BioMed Central Ltd
Journal title:Critical care (London, England), 2018-11, Vol.22 (1), p.302-302, Article 302
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Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks
Author / Creator:Zamora, Ruben ; Chavan, Sangeeta ; Zanos, Theodoros ; Simmons, Richard L ; Billiar, Timothy R ; Vodovotz, Yoram
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2021-06, Vol.27 (1), p.65-65, Article 65
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ArticlesPeer ReviewedFull Text
Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies
Author / Creator:Ziraldo, Cordelia ; Vodovotz, Yoram ; Namas, Rami A ; Almahmoud, Khalid ; Tapias, Victor ; Mi, Qi ; Barclay, Derek ; Jefferson, Bahiyyah S ; Chen, Guoqiang ; Billiar, Timothy R ; Zamora, Ruben
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-12, Vol.8 (12), p.e79804-e79804
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Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain
Author / Creator:Guo, Xinfeng ; Wiley, Clayton A ; Steinman, Richard A ; Sheng, Yi ; Ji, Beihong ; Wang, Junmei ; Zhang, Liyong ; Wang, Tony ; Zenatai, Mazen ; Billiar, Timothy R ; Wang, Qingde
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2021-07, Vol.18 (1), p.169-169, Article 169
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A Janus tale of two active high mobility group box 1 (HMGB1) redox states
Author / Creator:Tang, Daolin ; Billiar, Timothy R ; Lotze, Michael T
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2012-10, Vol.18 (10), p.1360-1362
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Augmenting autophagy to treat acute kidney injury during endotoxemia in mice
Author / Creator:Howell, Gina M ; Gomez, Hernando ; Collage, Richard D ; Loughran, Patricia ; Zhang, Xianghong ; Escobar, Daniel A ; Billiar, Timothy R ; Zuckerbraun, Brian S ; Rosengart, Matthew R
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-07, Vol.8 (7), p.e69520
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ArticlesPeer ReviewedFull Text
Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis
Author / Creator:Lai, Dengming ; Tang, Jing ; Chen, Linsong ; Fan, Erica K. ; Scott, Melanie J. ; Li, Yuehua ; Billiar, Timothy R. ; Wilson, Mark A. ; Fang, Xiangming ; Shu, Qiang ; Fan, Jie
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-03, Vol.9 (3), p.369-12, Article 369
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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway
Author / Creator:Tang, Da ; Fu, Guang ; Li, Wenbo ; Sun, Ping ; Loughran, Patricia A ; Deng, Meihong ; Scott, Melanie J ; Billiar, Timothy R
Publisher:England: BioMed Central
Journal title:Molecular medicine (Cambridge, Mass.), 2021-02, Vol.27 (1), p.18-18, Article 18
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Billiar, Timothy R

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Billiar, Timothy R

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Inflammasome and autophagy regulation - a two-way street

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PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation

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PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis

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iNOS promotes CD24⁺CD133⁺ liver cancer stem cell phenotype through a TACE/ADAM17-dependent Notch signaling pathway

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IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model

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Time for trauma immunology

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Intracellular HMGB1 as a novel tumor suppressor of pancreatic cancer

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Cytosolic HMGB1 controls the cellular autophagy/apoptosis checkpoint during inflammation

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Targeting adaptor protein SLP76 of RAGE as a therapeutic approach for lethal sepsis

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HMGB1 released from nociceptors mediates inflammation

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Mechanical ventilation enhances extrapulmonary sepsis-induced lung injury: role of WISP1-αvβ5 integrin pathway in TLR4-mediated inflammation and injury

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Spatiotemporally specific roles of TLR4, TNF, and IL-17A in murine endotoxin-induced inflammation inferred from analysis of dynamic networks

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Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies

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Aicardi-Goutières syndrome-associated mutation at ADAR1 gene locus activates innate immune response in mouse brain

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A Janus tale of two active high mobility group box 1 (HMGB1) redox states

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Augmenting autophagy to treat acute kidney injury during endotoxemia in mice

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Group 2 innate lymphoid cells protect lung endothelial cells from pyroptosis in sepsis

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Maresin 1 protects the liver against ischemia/reperfusion injury via the ALXR/Akt signaling pathway

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