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312 results for Biomarkers,+Tumor+-+antagonists+

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ArticlesPeer ReviewedFull Text
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
Author / Creator:Le, Dung T. ; Durham, Jennifer N. ; Smith, Kellie N. ; Wang, Hao ; Bartlett, Bjarne R. ; Aulakh, Laveet K. ; Lu, Steve ; Kemberling, Holly ; Wilt, Cara ; Luber, Brandon S. ; Wong, Fay ; Azad, Nilofer S. ; Rucki, Agnieszka A. ; Laheru, Dan ; Donehower, Ross ; Zaheer, Atif ; Fisher, George A. ; Crocenzi, Todd S. ; Lee, James J. ; Greten, Tim F. ; Duffy, Austin G. ; Ciombor, Kristen K. ; Eyring, Aleksandra D. ; Lam, Bao H. ; Joe, Andrew ; Kang, S. Peter ; Holdhoff, Matthias ; Danilova, Ludmila ; Cope, Leslie ; Meyer, Christian ; Zhou, Shibin ; Goldberg, Richard M. ; Armstrong, Deborah K. ; Bever, Katherine M. ; Fader, Amanda N. ; Taube, Janis ; Housseau, Franck ; Spetzler, David ; Xiao, Nianqing ; Pardoll, Drew M. ; Papadopoulos, Nickolas ; Kinzler, Kenneth W. ; Eshleman, James R. ; Vogelstein, Bert ; Anders, Robert A. ; Diaz, Luis A.
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-07, Vol.357 (6349), p.409-413
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Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study
Author / Creator:Solomon, Benjamin J, Prof ; Besse, Benjamin, Prof ; Bauer, Todd M, MD ; Felip, Enriqueta, MD ; Soo, Ross A, MD ; Camidge, D Ross, Prof ; Chiari, Rita, MD ; Bearz, Alessandra, MD ; Lin, Chia-Chi, MD ; Gadgeel, Shirish M, Prof ; Riely, Gregory J, MD ; Tan, Eng Huat, MBBS ; Seto, Takashi, Prof ; James, Leonard P, MD ; Clancy, Jill S, BS ; Abbattista, Antonello, BSc ; Martini, Jean-François, PhD ; Chen, Joseph, PharmD ; Peltz, Gerson, MD ; Thurm, Holger, MD ; Ou, Sai-Hong Ignatius, Prof ; Shaw, Alice T, Prof
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-12, Vol.19 (12), p.1654-1667
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Pore-forming activity and structural autoinhibition of the gasdermin family
Author / Creator:Ding, Jingjin ; Wang, Kun ; Liu, Wang ; She, Yang ; Sun, Qi ; Shi, Jianjin ; Sun, Hanzi ; Wang, Da-Cheng ; Shao, Feng
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2016-07, Vol.535 (7610), p.111-116
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Role of STAT3 signaling pathway in breast cancer
Author / Creator:Ma, Jia-hui ; Qin, Li ; Li, Xia
Publisher:England: BioMed Central
Journal title:Cell communication and signaling, 2020-02, Vol.18 (1), p.33-13, Article 33
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Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...
Author / Creator:Tabernero, Josep ; Hoff, Paulo M ; Shen, Lin ; Ohtsu, Atsushi ; Shah, Manish A ; Cheng, Karen ; Song, Chunyan ; Wu, Haiyan ; Eng-Wong, Jennifer ; Kim, Katherine ; Kang, Yoon-Koo
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-10, Vol.19 (10), p.1372-1384
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Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm
Author / Creator:Nakamura, Yoshiaki ; Kawazoe, Akihito ; Lordick, Florian ; Janjigian, Yelena Y. ; Shitara, Kohei
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2021-08, Vol.18 (8), p.473-487
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Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials
Author / Creator:Drilon, Alexander, MD ; Siena, Salvatore, Prof ; Dziadziuszko, Rafal, MD ; Barlesi, Fabrice, MD ; Krebs, Matthew G, MD ; Shaw, Alice T, Prof ; de Braud, Filippo, Prof ; Rolfo, Christian, MD ; Ahn, Myung-Ju, MD ; Wolf, Jürgen, Prof ; Seto, Takashi, MD ; Cho, Byoung Chul, Prof ; Patel, Manish R, MD ; Chiu, Chao-Hua, MD ; John, Thomas, MD ; Goto, Koichi, MD ; Karapetis, Christos S, Prof ; Arkenau, Hendrick-Tobias, MD ; Kim, Sang-We, MD ; Ohe, Yuichiro, MD ; Li, Yu-Chung, MD ; Chae, Young K, MD ; Chung, Christine H, Prof ; Otterson, Gregory A, Prof ; Murakami, Haruyasu, MD ; Lin, Chia-Chi, MD ; Tan, Daniel S W, MD ; Prenen, Hans, Prof ; Riehl, Todd, PharmD ; Chow-Maneval, Edna, PhD ; Simmons, Brian, PharmD ; Cui, Na, PhD ; Johnson, Ann, MS ; Eng, Susan, PharmD ; Wilson, Timothy R, PhD ; Doebele, Robert C, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2020-02, Vol.21 (2), p.261-270
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ArticlesPeer ReviewedFull Text
B-cell maturation antigen (BCMA) in multiple myeloma: rationale for targeting and current therapeutic approaches
Author / Creator:Shah, Nina ; Chari, Ajai ; Scott, Emma ; Mezzi, Khalid ; Usmani, Saad Z.
Publisher:London: Nature Publishing Group UK
Journal title:Leukemia, 2020-04, Vol.34 (4), p.985-1005
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ArticlesPeer ReviewedFull Text
The significance of exosomes in the development and treatment of hepatocellular carcinoma
Author / Creator:Li, Xin ; Li, Chuanyun ; Zhang, Liping ; Wu, Min ; Cao, Ke ; Jiang, Feifei ; Chen, Dexi ; Li, Ning ; Li, Weihua
Publisher:England: BioMed Central Ltd
Journal title:Molecular cancer, 2020-01, Vol.19 (1), p.1-11, Article 1
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ArticlesPeer ReviewedFull Text
Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study
Author / Creator:Laetsch, Theodore W ; DuBois, Steven G ; Mascarenhas, Leo ; Turpin, Brian ; Federman, Noah ; Albert, Catherine M ; Nagasubramanian, Ramamoorthy ; Davis, Jessica L ; Rudzinski, Erin ; Feraco, Angela M ; Tuch, Brian B ; Ebata, Kevin T ; Reynolds, Mark ; Smith, Steven ; Cruickshank, Scott ; Cox, Michael C ; Pappo, Alberto S ; Hawkins, Douglas S
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2018-05, Vol.19 (5), p.705-714
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ArticlesPeer ReviewedFull Text
Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study
Author / Creator:Swain, Sandra M, Dr ; Kim, Sung-Bae, MD ; Cortés, Javier, MD ; Ro, Jungsil, MD ; Semiglazov, Vladimir, MD ; Campone, Mario, MD ; Ciruelos, Eva, MD ; Ferrero, Jean-Marc, MD ; Schneeweiss, Andreas, MD ; Knott, Adam, PhD ; Clark, Emma, MSc ; Ross, Graham, FFPM ; Benyunes, Mark C, MD ; Baselga, José, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-05, Vol.14 (6), p.461-471
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ArticlesPeer ReviewedFull Text
Pre-clinical modeling of cutaneous melanoma
Author / Creator:Rebecca, Vito W. ; Somasundaram, Rajasekharan ; Herlyn, Meenhard
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2020-06, Vol.11 (1), p.2858-9, Article 2858
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Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phas...
Author / Creator:Gianni, Luca, Dr ; Pienkowski, Tadeusz, Prof ; Im, Young-Hyuck, Prof ; Roman, Laslo, MD ; Tseng, Ling-Ming, MD ; Liu, Mei-Ching, MD ; Lluch, Ana, MD ; Staroslawska, Elżbieta, Prof ; de la Haba-Rodriguez, Juan, MD ; Im, Seock-Ah, Prof ; Pedrini, Jose Luiz, MD ; Poirier, Brigitte, MD ; Morandi, Paolo, MD ; Semiglazov, Vladimir, Prof ; Srimuninnimit, Vichien, Prof ; Bianchi, Giulia, MD ; Szado, Tania, PhD ; Ratnayake, Jayantha, BSc ; Ross, Graham, MD ; Valagussa, Pinuccia, BS
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2012, Vol.13 (1), p.25-32
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Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC
Author / Creator:Ferrari, Paola ; Scatena, Cristian ; Ghilli, Matteo ; Bargagna, Irene ; Lorenzini, Giulia ; Nicolini, Andrea
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2022-01, Vol.23 (3), p.1665
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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets
Author / Creator:Dempster, Joshua M. ; Pacini, Clare ; Pantel, Sasha ; Behan, Fiona M. ; Green, Thomas ; Krill-Burger, John ; Beaver, Charlotte M. ; Younger, Scott T. ; Zhivich, Victor ; Najgebauer, Hanna ; Allen, Felicity ; Gonçalves, Emanuel ; Shepherd, Rebecca ; Doench, John G. ; Yusa, Kosuke ; Vazquez, Francisca ; Parts, Leopold ; Boehm, Jesse S. ; Golub, Todd R. ; Hahn, William C. ; Root, David E. ; Garnett, Mathew J. ; Tsherniak, Aviad ; Iorio, Francesco
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-12, Vol.10 (1), p.5817-14, Article 5817
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Relevance of deep learning to facilitate the diagnosis of HER2 status in breast cancer
Author / Creator:Vandenberghe, Michel E. ; Scott, Marietta L. J. ; Scorer, Paul W. ; Söderberg, Magnus ; Balcerzak, Denis ; Barker, Craig
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-04, Vol.7 (1), p.45938, Article 45938
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Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants
Author / Creator:De Rosa, Veronica ; Galgani, Mario ; Porcellini, Antonio ; Colamatteo, Alessandra ; Santopaolo, Marianna ; Zuchegna, Candida ; Romano, Antonella ; De Simone, Salvatore ; Procaccini, Claudio ; La Rocca, Claudia ; Carrieri, Pietro Biagio ; Maniscalco, Giorgia Teresa ; Salvetti, Marco ; Buscarinu, Maria Chiara ; Franzese, Adriana ; Mozzillo, Enza ; La Cava, Antonio ; Matarese, Giuseppe
Publisher:New York: Nature Publishing Group US
Journal title:Nature immunology, 2015-11, Vol.16 (11), p.1174-1184
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Progress in refining the clinical management of cancer of unknown primary in the molecular era
Author / Creator:Rassy, Elie ; Pavlidis, Nicholas
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2020-09, Vol.17 (9), p.541-554
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Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial
Author / Creator:Baselga, José, Dr ; Bradbury, Ian, PhD ; Eidtmann, Holger, MD ; Di Cosimo, Serena, MD ; de Azambuja, Evandro, MD ; Aura, Claudia, MD ; Gómez, Henry, MD ; Dinh, Phuong, MD ; Fauria, Karine, PhD ; Van Dooren, Veerle, MSc ; Aktan, Gursel, MD ; Goldhirsch, Aron, MD ; Chang, Tsai-Wang, MD ; Horváth, Zsolt, MD ; Coccia-Portugal, Maria, MD ; Domont, Julien, MD ; Tseng, Ling-Min, MD ; Kunz, Georg, MD ; Sohn, Joo Hyuk, MD ; Semiglazov, Vladimir, MD ; Lerzo, Guillermo, MD ; Palacova, Marketa, MD ; Probachai, Volodymyr, MD ; Pusztai, Lajos, DPhil ; Untch, Michael, PhD ; Gelber, Richard D, PhD ; Piccart-Gebhart, Martine, PhD
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2012-02, Vol.379 (9816), p.633-640
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Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial
Author / Creator:Waddell, Tom, MBBCh ; Chau, Ian, MD ; Cunningham, David, Prof ; Gonzalez, David, PhD ; Okines, Alicia Frances Clare, MBBCh ; Wotherspoon, Andrew, MBBCh ; Saffery, Claire ; Middleton, Gary, MD ; Wadsley, Jonathan, MBBCh ; Ferry, David, Prof ; Mansoor, Wasat, PhD ; Crosby, Tom, MBBS ; Coxon, Fareeda, MBBS ; Smith, David, MD ; Waters, Justin, PhD ; Iveson, Timothy, MD ; Falk, Stephen, MD ; Slater, Sarah, MD ; Peckitt, Clare, MSc ; Barbachano, Yolanda, PhD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2013-05, Vol.14 (6), p.481-489
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Showing 1 to 20 of 312 results

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Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade

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Lorlatinib in patients with ALK-positive non-small-cell lung cancer: results from a global phase 2 study

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Pore-forming activity and structural autoinhibition of the gasdermin family

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Role of STAT3 signaling pathway in breast cancer

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Pertuzumab plus trastuzumab and chemotherapy for HER2-positive metastatic gastric or gastro-oesophageal junction cancer (JACOB): final analysis of a double-blind, randomised, placebo-controlled phase...

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Biomarker-targeted therapies for advanced-stage gastric and gastro-oesophageal junction cancers: an emerging paradigm

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Entrectinib in ROS1 fusion-positive non-small-cell lung cancer: integrated analysis of three phase 1–2 trials

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B-cell maturation antigen (BCMA) in multiple myeloma: rationale for targeting and current therapeutic approaches

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The significance of exosomes in the development and treatment of hepatocellular carcinoma

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Larotrectinib for paediatric solid tumours harbouring NTRK gene fusions: phase 1 results from a multicentre, open-label, phase 1/2 study

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Pertuzumab, trastuzumab, and docetaxel for HER2-positive metastatic breast cancer (CLEOPATRA study): overall survival results from a randomised, double-blind, placebo-controlled, phase 3 study

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Pre-clinical modeling of cutaneous melanoma

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Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phas...

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Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC

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Agreement between two large pan-cancer CRISPR-Cas9 gene dependency data sets

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Relevance of deep learning to facilitate the diagnosis of HER2 status in breast cancer

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Glycolysis controls the induction of human regulatory T cells by modulating the expression of FOXP3 exon 2 splicing variants

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Progress in refining the clinical management of cancer of unknown primary in the molecular era

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Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): a randomised, open-label, multicentre, phase 3 trial

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Epirubicin, oxaliplatin, and capecitabine with or without panitumumab for patients with previously untreated advanced oesophagogastric cancer (REAL3): a randomised, open-label phase 3 trial

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