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Newsletter articlesFull Text
Boschi Donatella, Giorgis Marta, Lolli Marco Lucio, Martinelli Giovanni and Saglio Giuseppe Apply for Patent on Novel Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors and Their Use in Targeting...
Publisher:New Delhi: Pedia Content Solutions Pvt. Ltd
Journal title:Global IP News. Pharmaceutical Patent News, 2021
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ArticlesPeer ReviewedFull Text
The Novel hDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis
Author / Creator:Sibille, Giulia ; Luganini, Anna ; Sainas, Stefano ; Boschi, Donatella ; Lolli, Marco Lucio ; Gribaudo, Giorgio
Publisher:Basel: MDPI AG
Journal title:Viruses, 2022-10, Vol.14 (10), p.2281
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ArticlesPeer ReviewedFull Text
Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study
Author / Creator:Galati, Salvatore ; Sainas, Stefano ; Giorgis, Marta ; Boschi, Donatella ; Lolli, Marco L. ; Ortore, Gabriella ; Poli, Giulio ; Tuccinardi, Tiziano
Publisher:Basel: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2022-06, Vol.27 (12), p.3660
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ArticlesPeer ReviewedFull Text
Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia
Author / Creator:Houshmand, Mohammad ; Vitale, Nicoletta ; Orso, Francesca ; Cignetti, Alessandro ; Molineris, Ivan ; Gaidano, Valentina ; Sainas, Stefano ; Giorgis, Marta ; Boschi, Donatella ; Fava, Carmen ; Passoni, Alice ; Gai, Marta ; Geuna, Massimo ; Sora, Federica ; Iurlo, Alessandra ; Abruzzese, Elisabetta ; Breccia, Massimo ; Mulas, Olga ; Caocci, Giovanni ; Castagnetti, Fausto ; Taverna, Daniela ; Oliviero, Salvatore ; Pane, Fabrizio ; Lolli, Marco Lucio ; Circosta, Paola ; Saglio, Giuseppe
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2022-06, Vol.13 (6), p.576-13, Article 576
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ArticlesPeer ReviewedFull Text
The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses
Author / Creator:Calistri, Arianna ; Luganini, Anna ; Mognetti, Barbara ; Elder, Elizabeth ; Sibille, Giulia ; Conciatori, Valeria ; Del Vecchio, Claudia ; Sainas, Stefano ; Boschi, Donatella ; Montserrat, Nuria ; Mirazimi, Ali ; Lolli, Marco Lucio ; Gribaudo, Giorgio ; Parolin, Cristina
Publisher:Basel: MDPI AG
Journal title:Microorganisms (Basel), 2021-08, Vol.9 (8), p.1731
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ArticlesPeer ReviewedFull Text
A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats
Author / Creator:Rubin, Elina ; Pippione, Agnese C ; Boyko, Matthew ; Einaudi, Giacomo ; Sainas, Stefano ; Collino, Massimo ; Cifani, Carlo ; Lolli, Marco L ; Abu-Freha, Naim ; Kaplanski, Jacob ; Boschi, Donatella ; Azab, Abed N
Publisher:Switzerland: MDPI AG
Journal title:Brain sciences, 2021-12, Vol.12 (1), p.35
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ArticlesPeer ReviewedFull Text
Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis
Author / Creator:Wróbel, Tomasz M ; Sharma, Katyayani ; Mannella, Iole ; Oliaro-Bosso, Simonetta ; Nieckarz, Patrycja ; Du Toit, Therina ; Voegel, Clarissa Daniela ; Rojas Velazquez, Maria Natalia ; Yakubu, Jibira ; Matveeva, Anna ; Therkelsen, Søren ; Jørgensen, Flemming Steen ; Pandey, Amit V ; Pippione, Agnese C ; Lolli, Marco L ; Boschi, Donatella ; Björkling, Fredrik
Publisher:Basel: MDPI AG
Journal title:Biomolecules (Basel, Switzerland), 2023-09, Vol.13 (9), p.1349
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ArticlesPeer ReviewedFull Text
The Novel Ih/IDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis
Author / Creator:Sibille, Giulia ; Luganini, Anna ; Sainas, Stefano ; Boschi, Donatella ; Lolli, Marco Lucio ; Gribaudo, Giorgio
Publisher:MDPI AG
Journal title:Viruses, 2022-10, Vol.14 (10)
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ArticlesPeer ReviewedFull Text
The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia
Author / Creator:Gaidano, Valentina ; Houshmand, Mohammad ; Vitale, Nicoletta ; Carrà, Giovanna ; Morotti, Alessandro ; Tenace, Valerio ; Rapelli, Stefania ; Sainas, Stefano ; Pippione, Agnese Chiara ; Giorgis, Marta ; Boschi, Donatella ; Lolli, Marco Lucio ; Cilloni, Daniela ; Cignetti, Alessandro ; Saglio, Giuseppe ; Circosta, Paola
Publisher:Switzerland: MDPI AG
Journal title:Cancers, 2021-02, Vol.13 (5), p.1003
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ArticlesPeer ReviewedFull Text
Searching for balanced hybrid NO-donor 1,4-dihydropyridines with basic properties
Author / Creator:BOSCHI, Donatella ; CARON, Giulia ; VISENTIN, Sonja ; DI STILO, Antonella ; ROLANDO, Barbara ; FRUTTERO, Roberta ; GASCO, Alberto
Publisher:New York, NY: Springer
Journal title:Pharmaceutical research, 2001-07, Vol.18 (7), p.987-991
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ArticlesPeer ReviewedFull Text
Mechanisms of liposomes/water partitioning of (p-methylbenzyl)alkylamines
Author / Creator:FRUTTERO, R ; CARON, G ; FORNATTO, E ; BOSCHI, D ; ERMONDI, G ; GASCO, A ; CARRUPT, P.-A ; TESTA, B
Publisher:New York, NY: Springer
Journal title:Pharmaceutical research, 1998-09, Vol.15 (9), p.1407-1413
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ArticlesPeer ReviewedFull Text
Studies on agents with mixed NO-dependent and calcium channel antagonistic vasodilating activities
Author / Creator:CENA, Clara ; VISENTIN, Sonja ; DI STILO, Antonella ; BOSCHI, Donatella ; FRUTTERO, Roberta ; GASCO, Alberto
Publisher:New York, NY: Springer
Journal title:Pharmaceutical research, 2001-02, Vol.18 (2), p.157-165
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ArticlesPeer ReviewedFull Text
Studies on Agents with Mixed NO-Dependent Vasodilating and [beta]-Blocking Activities
Author / Creator:Boschi, Donatella ; Antonella Di Stilo ; Cena, Clara ; Lolli, Marco
Publisher:New York: Springer Nature B.V
Journal title:Pharmaceutical research, 1997-12, Vol.14 (12), p.1750
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ArticlesFull Text
The new generation hDHODH inhibitor MEDS433 hinders the in vitro replication of SARS-CoV-2
Author / Creator:Calistri, Arianna ; Luganini, Anna ; Conciatori, Valeria ; Claudia Del Vecchio ; Sainas, Stefano ; Boschi, Donatella ; Marco Lucio Lolli ; Gribaudo, Giorgio ; Parolin, Cristina
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-12
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ArticlesFull Text
The Synergism Between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia
Author / Creator:Gaidano, Valentina ; Houshmand, Mohammad ; Vitale, Nicoletta ; Carrà, Giovanna ; Morotti, Alessandro ; Tenace, Valerio ; Rapelli, Stefania ; Sainas, Stefano ; Agnese Chiara Pippione ; Giorgis, Marta ; Boschi, Donatella ; Marco Lucio Lolli ; Cignetti, Alessandro ; Saglio, Giuseppe ; Circosta, Paola
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2020-10
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Boschi Donatella, Giorgis Marta, Lolli Marco Lucio, Martinelli Giovanni and Saglio Giuseppe Apply for Patent on Novel Human Dihydroorotate Dehydrogenase (hDHODH) Inhibitors and Their Use in Targeting...

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The Novel hDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis

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Identification of Human Dihydroorotate Dehydrogenase Inhibitor by a Pharmacophore-Based Virtual Screening Study

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Dihydroorotate dehydrogenase inhibition reveals metabolic vulnerability in chronic myeloid leukemia

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The New Generation hDHODH Inhibitor MEDS433 Hinders the In Vitro Replication of SARS-CoV-2 and Other Human Coronaviruses

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A New NF-κB Inhibitor, MEDS-23, Reduces the Severity of Adverse Post-Ischemic Stroke Outcomes in Rats

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Exploring the Potential of Sulfur Moieties in Compounds Inhibiting Steroidogenesis

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The Novel Ih/IDHODH Inhibitor MEDS433 Prevents Influenza Virus Replication by Blocking Pyrimidine Biosynthesis

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The Synergism between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia

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Searching for balanced hybrid NO-donor 1,4-dihydropyridines with basic properties

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Mechanisms of liposomes/water partitioning of (p-methylbenzyl)alkylamines

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Studies on agents with mixed NO-dependent and calcium channel antagonistic vasodilating activities

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Studies on Agents with Mixed NO-Dependent Vasodilating and [beta]-Blocking Activities

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The new generation hDHODH inhibitor MEDS433 hinders the in vitro replication of SARS-CoV-2

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The Synergism Between DHODH Inhibitors and Dipyridamole Leads to Metabolic Lethality in Acute Myeloid Leukemia

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