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37 results for CCR5+Receptor+Antagonists+-+pharmacology

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ArticlesPeer ReviewedFull Text
Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis
Author / Creator:Lefebvre, Eric ; Moyle, Graeme ; Reshef, Ran ; Richman, Lee P. ; Thompson, Melanie ; Hong, Feng ; Chou, Hsin-l ; Hashiguchi, Taishi ; Plato, Craig ; Poulin, Dominic ; Richards, Toni ; Yoneyama, Hiroyuki ; Jenkins, Helen ; Wolfgang, Grushenka ; Friedman, Scott L.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2016-06, Vol.11 (6), p.e0158156
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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations
Author / Creator:Lowe, Patrick P. ; Morel, Caroline ; Ambade, Aditya ; Iracheta-Vellve, Arvin ; Kwiatkowski, Erica ; Satishchandran, Abhishek ; Furi, Istvan ; Cho, Yeonhee ; Gyongyosi, Benedek ; Catalano, Donna ; Lefebvre, Eric ; Fischer, Laurent ; Seyedkazemi, Star ; Schafer, Dorothy P. ; Szabo, Gyongyi
Publisher:England: BioMed Central Ltd
Journal title:Journal of neuroinflammation, 2020-10, Vol.17 (1), p.296-296, Article 296
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CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions
Author / Creator:Amorim Sacramento, Laís ; Farias Amorim, Camila ; G. Lombana, Claudia ; Beiting, Daniel ; Novais, Fernanda ; P. Carvalho, Lucas ; M. Carvalho, Edgar ; Scott, Phillip
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2024-05, Vol.20 (5), p.e1012211
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Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents
Author / Creator:Sharif, Ayni ; Jeffers, Matthew S ; Fergusson, Dean A ; Bapuji, Raj ; Nicholls, Stuart G ; Humphrey, John ; Johnston, Warren ; Mitchell, Ed ; Speirs, Mary-Ann ; Stronghill, Laura ; Vuckovic, Michele ; Wulf, Susan ; Shorr, Risa ; Dowlatshahi, Dar ; Corbett, Dale ; Lalu, Manoj M
Publisher:England: eLife Sciences Publications, Ltd
Journal title:eLife, 2025-04, Vol.14
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Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy
Author / Creator:Jiao, Xuanmao ; Wang, Min ; Zhang, Zhao ; Li, Zhiping ; Ni, Dong ; Ashton, Anthony W. ; Tang, Hsin-Yao ; Speicher, David W. ; Pestell, Richard G.
Publisher:England: BioMed Central Ltd
Journal title:Breast cancer research : BCR, 2021-01, Vol.23 (1), p.11-11, Article 11
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High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells
Author / Creator:De La Torre Tarazona, Erick ; Passaes, Caroline ; Moreno, Santiago ; Sáez-Cirión, Asier ; Alcamí, José
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2024-06, Vol.14 (1), p.13980-9, Article 13980
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A New Application for Cenicriviroc, a Dual CCR2/CCR5 Antagonist, in the Treatment of Painful Diabetic Neuropathy in a Mouse Model
Author / Creator:Bober, Aleksandra ; Piotrowska, Anna ; Pawlik, Katarzyna ; Ciapała, Katarzyna ; Maciuszek, Magdalena ; Makuch, Wioletta ; Mika, Joanna
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-07, Vol.25 (13), p.7410
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Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection
Author / Creator:Warner, Bryce M. ; Vendramelli, Robert ; Boese, Amrit S. ; Audet, Jonathan ; Tailor, Nikesh ; Meilleur, Courtney ; Glowach, Nathan ; Willman, Marnie ; Truong, Thang ; Moffat, Estella ; Tierney, Kevin ; Kosak, Beata ; Dhanidina, Irfan ; Engstrom, Jarret ; Korczak, Bozena ; McGowan, Ian ; Embury-Hyatt, Carissa ; Kobasa, Darwyn
Publisher:United States: Public Library of Science
Journal title:PloS one, 2025-02, Vol.20 (2), p.e0316952
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A novel small-molecular CCR5 antagonist promotes neural repair after stroke
Author / Creator:Wu, Qing-lin ; Cui, Li-yuan ; Ma, Wen-yu ; Wang, Sha-sha ; Zhang, Zhao ; Feng, Zhong-ping ; Sun, Hong-shuo ; Chu, Shi-feng ; He, Wen-bin ; Chen, Nai-hong
Publisher:Singapore: Springer Nature Singapore
Journal title:Acta pharmacologica Sinica, 2023-10, Vol.44 (10), p.1935-1947
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The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer
Author / Creator:Ward, S T ; Li, K K ; Hepburn, E ; Weston, C J ; Curbishley, S M ; Reynolds, G M ; Hejmadi, R K ; Bicknell, R ; Eksteen, B ; Ismail, T ; Rot, A ; Adams, D H
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2015-01, Vol.112 (2), p.319-328
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Antineoplastic effects of targeting CCR5 and its therapeutic potential for colorectal cancer liver metastasis
Author / Creator:Pervaiz, Asim ; Zepp, Michael ; Georges, Rania ; Bergmann, Frank ; Mahmood, Saqib ; Faiza, Syeda ; Berger, Martin R. ; Adwan, Hassan
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Journal of cancer research and clinical oncology, 2021-01, Vol.147 (1), p.73-91
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Sex Affects Cognitive Outcomes in HIV-1 Tat Transgenic Mice: Role of CCR5
Author / Creator:Simons, Chloe A. ; Kim, Sarah ; Hahn, Yun K. ; Boake-Agyei, Ama ; Nass, Sara R. ; Vo, Phu ; Hauser, Kurt F. ; Knapp, Pamela E.
Publisher:United States: Taylor & Francis
Journal title:ASN neuro, 2025-12, Vol.17 (1), p.2447338
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Co-receptor signaling in the pathogenesis of neuroHIV
Author / Creator:Nickoloff-Bybel, E. A. ; Festa, L. ; Meucci, O. ; Gaskill, P. J.
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2021-08, Vol.18 (1), p.24-24, Article 24
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Dopamine Receptor Activation Increases HIV Entry into Primary Human Macrophages
Author / Creator:Gaskill, Peter J. ; Yano, Hideaki H. ; Kalpana, Ganjam V. ; Javitch, Jonathan A. ; Berman, Joan W.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-09, Vol.9 (9), p.e108232
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ArticlesPeer ReviewedFull Text
A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus
Author / Creator:McCarthy, Stephen D. S. ; Majchrzak-Kita, Beata ; Racine, Trina ; Kozlowski, Hannah N. ; Baker, Darren P. ; Hoenen, Thomas ; Kobinger, Gary P. ; Fish, Eleanor N. ; Branch, Donald R.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2016-01, Vol.10 (1), p.e0004364-e0004364
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Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice
Author / Creator:Yan, Jun ; Xu, Weilin ; Lenahan, Cameron ; Huang, Lei ; Ocak, Umut ; Wen, Jing ; Li, Gaigai ; He, Wei ; Le, Chensheng ; Zhang, John H. ; Mo, Ligen ; Tang, Jiping
Publisher:England: BioMed Central Ltd
Journal title:Fluids and barriers of the CNS, 2022-01, Vol.19 (1), p.7-7, Article 7
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The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1
Author / Creator:López-Huertas, María Rosa ; Jiménez-Tormo, Laura ; Madrid-Elena, Nadia ; Gutiérrez, Carolina ; Rodríguez-Mora, Sara ; Coiras, Mayte ; Alcamí, José ; Moreno, Santiago
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-05, Vol.7 (1), p.2385-13, Article 2385
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A central role for glial CCR5 in directing the neuropathological interactions of HIV-1 Tat and opiates
Author / Creator:Kim, Sarah ; Hahn, Yun Kyung ; Podhaizer, Elizabeth M ; McLane, Virginia D ; Zou, Shiping ; Hauser, Kurt F ; Knapp, Pamela E
Publisher:England: BioMed Central
Journal title:Journal of neuroinflammation, 2018-10, Vol.15 (1), p.285-285, Article 285
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Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival
Author / Creator:Mora-Lagos, Bárbara ; Reyes, María Elena ; Lobos-Gonzalez, Lorena ; del Campo, Matías ; Buchegger, Kurt ; Zanella, Louise ; Riquelme, Ismael ; Ili, Carmen Gloria ; Brebi, Priscilla
Publisher:England: BioMed Central Ltd
Journal title:Biological research, 2025-01, Vol.58 (1), p.4-13, Article 4
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C-C Chemokine Ligand-5 is critical for facilitating macrophage infiltration in the early phase of liver ischemia/reperfusion injury
Author / Creator:Lee, Chiou-Mei ; Peng, Hsin-Hsin ; Yang, Polung ; Liou, Jiin-Tarng ; Liao, Chia-Chih ; Day, Yuan-Ji
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2017-06, Vol.7 (1), p.3698-13, Article 3698
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Showing 1 to 20 of 37 results

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Antifibrotic Effects of the Dual CCR2/CCR5 Antagonist Cenicriviroc in Animal Models of Liver and Kidney Fibrosis

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Chronic alcohol-induced neuroinflammation involves CCR2/5-dependent peripheral macrophage infiltration and microglia alterations

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CCR5 promotes the migration of pathological CD8+ T cells to the leishmanial lesions

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Preclinical systematic review of CCR5 antagonists as cerebroprotective and stroke recovery enhancing agents

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Leronlimab, a humanized monoclonal antibody to CCR5, blocks breast cancer cellular metastasis and enhances cell death induced by DNA damaging chemotherapy

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High concentrations of Maraviroc do not alter immunological and metabolic parameters of CD4 T cells

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A New Application for Cenicriviroc, a Dual CCR2/CCR5 Antagonist, in the Treatment of Painful Diabetic Neuropathy in a Mouse Model

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Treatment with the CCR5 antagonist OB-002 reduces lung pathology, but does not prevent disease in a Syrian hamster model of SARS-CoV-2 infection

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A novel small-molecular CCR5 antagonist promotes neural repair after stroke

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The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer

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Antineoplastic effects of targeting CCR5 and its therapeutic potential for colorectal cancer liver metastasis

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Sex Affects Cognitive Outcomes in HIV-1 Tat Transgenic Mice: Role of CCR5

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Co-receptor signaling in the pathogenesis of neuroHIV

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Dopamine Receptor Activation Increases HIV Entry into Primary Human Macrophages

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A Rapid Screening Assay Identifies Monotherapy with Interferon-ß and Combination Therapies with Nucleoside Analogs as Effective Inhibitors of Ebola Virus

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Met-RANTES preserves the blood–brain barrier through inhibiting CCR1/SRC/Rac1 pathway after intracerebral hemorrhage in mice

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The CCR5-antagonist Maraviroc reverses HIV-1 latency in vitro alone or in combination with the PKC-agonist Bryostatin-1

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A central role for glial CCR5 in directing the neuropathological interactions of HIV-1 Tat and opiates

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Maraviroc/cisplatin combination inhibits gastric cancer tumoroid growth and improves mice survival

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C-C Chemokine Ligand-5 is critical for facilitating macrophage infiltration in the early phase of liver ischemia/reperfusion injury

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