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71 results for Calcineurin+Inhibitors+-+pharmacology

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Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease
Author / Creator:Burbulla, Lena F. ; Song, Pingping ; Mazzulli, Joseph R. ; Zampese, Enrico ; Wong, Yvette C. ; Jeon, Sohee ; Santos, David P. ; Blanz, Judith ; Obermaier, Carolin D. ; Strojny, Chelsee ; Savas, Jeffrey N. ; Kiskinis, Evangelos ; Zhuang, Xiaoxi ; Krüger, Rejko ; Surmeier, D. James ; Krainc, Dimitri
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2017-09, Vol.357 (6357), p.1255-1261
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Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis
Author / Creator:Berends, Sophie E. ; Strik, Anne S. ; Löwenberg, Mark ; D’Haens, Geert R. ; Mathôt, Ron A. A.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2019-01, Vol.58 (1), p.15-37
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Voclosporin: First Approval
Author / Creator:Heo, Young-A
Publisher:Cham: Springer International Publishing
Journal title:Drugs (New York, N.Y.), 2021-04, Vol.81 (5), p.605-610
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Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive
Author / Creator:Miyata, Haruhiko ; Satouh, Yuhkoh ; Mashiko, Daisuke ; Muto, Masanaga ; Nozawa, Kaori ; Shiba, Kogiku ; Fujihara, Yoshitaka ; Isotani, Ayako ; Inaba, Kazuo ; Ikawa, Masahito
Publisher:United States: American Association for the Advancement of Science
Journal title:Science (American Association for the Advancement of Science), 2015-10, Vol.350 (6259), p.442-445
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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
Author / Creator:Juvvadi, Praveen R. ; Fox, David ; Bobay, Benjamin G. ; Hoy, Michael J. ; Gobeil, Sophie M. C. ; Venters, Ronald A. ; Chang, Zanetta ; Lin, Jackie J. ; Averette, Anna Floyd ; Cole, D. Christopher ; Barrington, Blake C. ; Wheaton, Joshua D. ; Ciofani, Maria ; Trzoss, Michael ; Li, Xiaoming ; Lee, Soo Chan ; Chen, Ying-Lien ; Mutz, Mitchell ; Spicer, Leonard D. ; Schumacher, Maria A. ; Heitman, Joseph ; Steinbach, William J.
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2019-09, Vol.10 (1), p.4275-18, Article 4275
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IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors
Author / Creator:Whitehouse, Gavin ; Gray, Elizabeth ; Mastoridis, Sotiris ; Merritt, Elliot ; Kodela, Elisavet ; Yang, Jennie H. M. ; Danger, Richard ; Mairal, Marta ; Christakoudi, Sofia ; Lozano, Juan J. ; Macdougall, Iain C. ; Tree, Timothy I. M. ; Sanchez-Fueyo, Alberto ; Martinez-Llordella, Marc
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7083-7088
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MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes
Author / Creator:Wu, Junnan ; Zheng, Chunxia ; Wang, Xiao ; Yun, Shifeng ; Zhao, Yue ; Liu, Lin ; Lu, Yuqiu ; Ye, Yuting ; Zhu, Xiaodong ; Zhang, Changming ; Shi, Shaolin ; Liu, Zhihong
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2015-11, Vol.125 (11), p.4091-4106
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Chronic Antibody-Mediated Rejection and Plasma Cell ER Stress: Opportunities and Challenges with Calcineurin Inhibitors
Author / Creator:Tsai, Ching-Yi ; Lee, Chih-Yuan ; Chen, Jia-Huang ; Chiang, Chih-Kang
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2025-03, Vol.26 (6), p.2711
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Inpatient Therapy With Calcineurin Inhibitors in Severe Ulcerative Colitis
Author / Creator:Dwadasi, Sujaata ; Zafer, Maryam ; Goens, Donald ; Paknikar, Raghavendra ; Dalal, Sushila ; Cohen, Russell D ; Pekow, Joel ; Rubin, David T ; Sakuraba, Atsushi ; Micic, Dejan
Publisher:US: Oxford University Press
Journal title:Inflammatory bowel diseases, 2021-10, Vol.27 (10), p.1620-1625
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Basic Science and Pathogenesis
Author / Creator:Santos, Sarah Tavares Araújo ; Gomes, Giovanni Freitas ; Rocha, Nádia Gomes ; Oliveira, Antônio Carlos Pinheiro
Publisher:United States
Journal title:Alzheimer's & dementia, 2024-12, Vol.20 Suppl 1, p.e086388
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Inhibition of Calcineurin with FK506 Reduces Tau Levels and Attenuates Synaptic Impairment Driven by Tau Oligomers in the Hippocampus of Male Mouse Models
Author / Creator:Marcatti, Michela ; Tumurbaatar, Batbayar ; Borghi, Michela ; Guptarak, Jutatip ; Zhang, Wen-Ru ; Krishnan, Balaji ; Kayed, Rakez ; Fracassi, Anna ; Taglialatela, Giulio
Publisher:Switzerland: MDPI AG
Journal title:International journal of molecular sciences, 2024-08, Vol.25 (16), p.9092
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Physalin F, a Potent Inhibitor of Lymphocyte Function, Is a Calcineurin Inhibitor and Has Synergistic Effect with Dexamethasone
Author / Creator:Silva, Dahara Keyse Carvalho ; Novo, Laura Beatriz da Cruz ; Ribeiro, Ivone Maria ; Barreto, Breno Cardim ; Opretzka, Luiza Carolina França ; Meira, Cássio Santana ; Soares, Milena Botelho Pereira
Publisher:Switzerland: MDPI AG
Journal title:Molecules (Basel, Switzerland), 2025-02, Vol.30 (4), p.916
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Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD
Author / Creator:Wang, Yewei ; Ullah, Md Ashik ; Waltner, Olivia G ; Bhise, Shruti S ; Ensbey, Kathleen S ; Schmidt, Christine R ; Legg, Samuel Rw ; Sekiguchi, Tomoko ; Nelson, Ethan L ; Kuns, Rachel D ; Nemychenkov, Nicole S ; Atilla, Erden ; Yeh, Albert C ; Takahashi, Shuichiro ; Boiko, Julie R ; Varelias, Antiopi ; Blazar, Bruce R ; Koyama, Motoko ; Minnie, Simone A ; Clouston, Andrew D ; Furlan, Scott N ; Zhang, Ping ; Hill, Geoffrey R
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2024-06, Vol.134 (11), p.1-17
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Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles
Author / Creator:Tucker Edmister, Sara ; Del Rosario Hernández, Thaís ; Ibrahim, Rahma ; Brown, Cameron A. ; Gore, Sayali V. ; Kakodkar, Rohit ; Kreiling, Jill A. ; Creton, Robbert
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2022-04, Vol.12 (1), p.6120-13, Article 6120
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Severity and organ distribution of chronic graft-versus-host disease with posttransplant cyclophosphamide-based versus methotrexate/calcineurin inhibitor-based allogeneic hematopoietic cell transplant...
Author / Creator:Chhabra, Saurabh ; Jerkins, James H. ; Monahan, Kathleen ; Szabo, Aniko ; Shah, Nirav N. ; Abedin, Sameem ; Runaas, Lyndsey ; Fenske, Timothy S. ; Pasquini, Marcelo C. ; Shaw, Bronwen E. ; Drobyski, William R. ; Saber, Wael ; D’Souza, Anita ; Dhakal, Binod ; Mohan, Meera ; Longo, Walter ; Hamadani, Mehdi
Publisher:London: Nature Publishing Group UK
Journal title:Bone marrow transplantation (Basingstoke), 2024-03, Vol.59 (3), p.373-379
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NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity
Author / Creator:Tutakhel, Omar A Z ; Moes, Arthur D ; Valdez-Flores, Marco A ; Kortenoeven, Marleen L A ; Vrie, Mathijs V D ; Jeleń, Sabina ; Fenton, Robert A ; Zietse, Robert ; Hoenderop, Joost G J ; Hoorn, Ewout J ; Hilbrands, Luuk ; Bindels, René J M
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-04, Vol.12 (4), p.e0176220-e0176220
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Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling
Author / Creator:Das, Priyanka ; Aballay, Alejandro ; Singh, Jogender
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2024-11, Vol.12
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Pharmacokinetics, Pharmacodynamics and Pharmacogenomics of Immunosuppressants in Allogeneic Haematopoietic Cell Transplantation: Part I
Author / Creator:McCune, Jeannine S. ; Bemer, Meagan J.
Publisher:Cham: Springer International Publishing
Journal title:Clinical pharmacokinetics, 2016-05, Vol.55 (5), p.525-550
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Calcineurin inactivation inhibits pyruvate dehydrogenase complex activity and induces the Warburg effect
Author / Creator:Zhang, Jianong ; Zhang, Liang ; Nie, Ji ; Lin, Yan ; Li, Yao ; Xu, Wei ; Zhao, Jian-Yuan ; Zhao, Shi-Min ; Wang, Chenji
Publisher:London: Nature Publishing Group UK
Journal title:Oncogene, 2021-12, Vol.40 (49), p.6692-6702
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How immunosuppressive drugs may directly target podocytes in glomerular diseases
Author / Creator:Salvadori, Maurizio ; Tsalouchos, Aris
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Pediatric nephrology (Berlin, West), 2022-07, Vol.37 (7), p.1431-1441
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Showing 1 to 20 of 71 results

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Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

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Clinical Pharmacokinetic and Pharmacodynamic Considerations in the Treatment of Ulcerative Colitis

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Voclosporin: First Approval

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Sperm calcineurin inhibition prevents mouse fertility with implications for male contraceptive

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Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents

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IL-2 therapy restores regulatory T-cell dysfunction induced by calcineurin inhibitors

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MicroRNA-30 family members regulate calcium/calcineurin signaling in podocytes

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Chronic Antibody-Mediated Rejection and Plasma Cell ER Stress: Opportunities and Challenges with Calcineurin Inhibitors

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Inpatient Therapy With Calcineurin Inhibitors in Severe Ulcerative Colitis

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Basic Science and Pathogenesis

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Inhibition of Calcineurin with FK506 Reduces Tau Levels and Attenuates Synaptic Impairment Driven by Tau Oligomers in the Hippocampus of Male Mouse Models

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Physalin F, a Potent Inhibitor of Lymphocyte Function, Is a Calcineurin Inhibitor and Has Synergistic Effect with Dexamethasone

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Calcineurin inhibition rescues alloantigen-specific central memory T cell subsets that promote chronic GVHD

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Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles

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Severity and organ distribution of chronic graft-versus-host disease with posttransplant cyclophosphamide-based versus methotrexate/calcineurin inhibitor-based allogeneic hematopoietic cell transplant...

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NaCl cotransporter abundance in urinary vesicles is increased by calcineurin inhibitors and predicts thiazide sensitivity

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Calcineurin inhibition enhances Caenorhabditis elegans lifespan by defecation defects-mediated calorie restriction and nuclear hormone signaling

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Pharmacokinetics, Pharmacodynamics and Pharmacogenomics of Immunosuppressants in Allogeneic Haematopoietic Cell Transplantation: Part I

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Calcineurin inactivation inhibits pyruvate dehydrogenase complex activity and induces the Warburg effect

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How immunosuppressive drugs may directly target podocytes in glomerular diseases

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