Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
About this item
Full title
Author / Creator
Han, Yuling , Duan, Xiaohua , Yang, Liuliu , Nilsson-Payant, Benjamin E. , Wang, Pengfei , Duan, Fuyu , Tang, Xuming , Yaron, Tomer M. , Zhang, Tuo , Uhl, Skyler , Bram, Yaron , Richardson, Chanel , Zhu, Jiajun , Zhao, Zeping , Redmond, David , Houghton, Sean , Nguyen, Duc-Huy T. , Xu, Dong , Wang, Xing , Jessurun, Jose , Borczuk, Alain , Huang, Yaoxing , Johnson, Jared L. , Liu, Yuru , Xiang, Jenny , Wang, Hui , Cantley, Lewis C. , tenOever, Benjamin R. , Ho, David D. , Pan, Fong Cheng , Evans, Todd , Chen, Huanhuan Joyce , Schwartz, Robert E. and Chen, Shuibing
Publisher
London: Nature Publishing Group UK
Journal title
Language
English
Formats
Publication information
Publisher
London: Nature Publishing Group UK
Subjects
More information
Scope and Contents
Contents
There is an urgent need to create novel models using human disease-relevant cells to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) biology and to facilitate drug screening. Here, as SARS-CoV-2 primarily infects the respiratory tract, we developed a lung organoid model using human pluripotent stem cells (hPSC-LOs). The hPSC-LOs...
Alternative Titles
Full title
Identification of SARS-CoV-2 inhibitors using lung and colonic organoids
Authors, Artists and Contributors
Author / Creator
Duan, Xiaohua
Yang, Liuliu
Nilsson-Payant, Benjamin E.
Wang, Pengfei
Duan, Fuyu
Tang, Xuming
Yaron, Tomer M.
Zhang, Tuo
Uhl, Skyler
Bram, Yaron
Richardson, Chanel
Zhu, Jiajun
Zhao, Zeping
Redmond, David
Houghton, Sean
Nguyen, Duc-Huy T.
Xu, Dong
Wang, Xing
Jessurun, Jose
Borczuk, Alain
Huang, Yaoxing
Johnson, Jared L.
Liu, Yuru
Xiang, Jenny
Wang, Hui
Cantley, Lewis C.
tenOever, Benjamin R.
Ho, David D.
Pan, Fong Cheng
Evans, Todd
Chen, Huanhuan Joyce
Schwartz, Robert E.
Chen, Shuibing
Identifiers
Primary Identifiers
Record Identifier
TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8034380
Permalink
https://devfeature-collection.sl.nsw.gov.au/record/TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_8034380
Other Identifiers
ISSN
0028-0836,1476-4687
E-ISSN
1476-4687
DOI
10.1038/s41586-020-2901-9
