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ArticlesPeer ReviewedFull Text
Marked progress in AL amyloidosis survival: a 40-year longitudinal natural history study
Author / Creator:Staron, Andrew ; Zheng, Luke ; Doros, Gheorghe ; Connors, Lawreen H. ; Mendelson, Lisa M. ; Joshi, Tracy ; Sanchorawala, Vaishali
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2021-08, Vol.11 (8), p.139-139, Article 139
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Features of atrial fibrillation in wild‐type transthyretin cardiac amyloidosis: a systematic review and clinical experience
Author / Creator:Mints, Yuliya Y. ; Doros, Gheorghe ; Berk, John L. ; Connors, Lawreen H. ; Ruberg, Frederick L.
Publisher:England: John Wiley & Sons, Inc
Journal title:ESC Heart Failure, 2018-10, Vol.5 (5), p.772-779
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Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease
Author / Creator:Klimtchuk, Elena S. ; Prokaeva, Tatiana ; Frame, Nicholas M. ; Abdullahi, Hassan A. ; Spencer, Brian ; Dasari, Surendra ; Cui, Haili ; Berk, John L. ; Kurtin, Paul J. ; Connors, Lawreen H. ; Gursky, Olga
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-07, Vol.115 (28), p.E6428-E6436
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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity
Author / Creator:Guan, Jian ; Mishra, Shikha ; Qiu, Yiling ; Shi, Jianru ; Trudeau, Kyle ; Las, Guy ; Liesa, Marc ; Shirihai, Orian S ; Connors, Lawreen H ; Seldin, David C ; Falk, Rodney H ; MacRae, Calum A ; Liao, Ronglih
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2014-11, Vol.6 (11), p.1493-1507
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Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis
Author / Creator:Connors, Lawreen H., PhD ; Prokaeva, Tatiana, MD, PhD ; Lim, Amareth, PhD ; Théberge, Roger, PhD ; Falk, Rodney H., MD ; Doros, Gheorghe, PhD ; Berg, Alan, MD ; Costello, Catherine E., PhD ; O'Hara, Carl, MD ; Seldin, David C., MD, PhD ; Skinner, Martha, MD
Publisher:United States: Mosby, Inc
Journal title:The American heart journal, 2009-10, Vol.158 (4), p.607-614
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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity
Author / Creator:Guan, Jian ; Mishra, Shikha ; Qiu, Yiling ; Shi, Jianru ; Trudeau, Kyle ; Las, Guy ; Liesa, Marc ; Shirihai, Orian S ; Connors, Lawreen H ; Seldin, David C ; Falk, Rodney H ; MacRae, Calum A ; Liao, Ronglih
Publisher:England: John Wiley & Sons, Inc
Journal title:EMBO molecular medicine, 2015-05, Vol.7 (5), p.688-688
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Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis
Author / Creator:Yunis, Adil ; Doros, Gheorge ; Luptak, Ivan ; Connors, Lawreen H. ; Sam, Flora
Publisher:United States: Elsevier Inc
Journal title:The American journal of cardiology, 2019-07, Vol.124 (1), p.122-130
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Predictors of Mortality in Light Chain Cardiac Amyloidosis with Heart Failure
Author / Creator:Tahir, Usman A. ; Doros, Gheorghe ; Kim, John S. ; Connors, Lawreen H. ; Seldin, David C. ; Sam, Flora
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2019-06, Vol.9 (1), p.8552-8552, Article 8552
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ArticlesPeer ReviewedFull Text
Race/ethnicity in systemic AL amyloidosis: perspectives on disease and outcome disparities
Author / Creator:Staron, Andrew ; Connors, Lawreen H. ; Zheng, Luke ; Doros, Gheorghe ; Sanchorawala, Vaishali
Publisher:London: Nature Publishing Group UK
Journal title:Blood cancer journal (New York), 2020-11, Vol.10 (11), p.118-118, Article 118
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Amyloidogenic Light Chains Induce Cardiomyocyte Contractile Dysfunction and Apoptosis via a Non-Canonical p38α MAPK Pathway
Author / Creator:Shi, Jianru ; Guan, Jian ; Jiang, Bingbing ; Brenner, Daniel A. ; del Monte, Federica ; Ward, Jennifer E. ; Connors, Lawreen H. ; Sawyer, Douglas B. ; Semigran, Marc J. ; Macgillivray, Thomas E. ; Seldin, David C. ; Falk, Rodney ; Liao, Ronglih ; Olson, Eric N.
Publisher:National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4188-4193
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ArticlesPeer ReviewedFull Text
Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity
Author / Creator:Guan, Jian ; Mishra, Shikha ; Shi, Jianru ; Plovie, Eva ; Qiu, Yiling ; Cao, Xin ; Gianni, Davide ; Jiang, Bingbing ; del Monte, Federica ; Connors, Lawreen H. ; Seldin, David C. ; Lavatelli, Francesca ; Rognoni, Paola ; Palladini, Giovanni ; Merlini, Giampaolo ; Falk, Rodney H. ; Semigran, Marc J. ; Dec, G. William ; MacRae, Calum A. ; Liao, Ronglih
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Basic research in cardiology, 2013-09, Vol.108 (5), p.378-378, Article 378
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ArticlesPeer ReviewedFull Text
Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt)
Author / Creator:Sikora, Jacquelyn L. ; Logue, Mark W. ; Chan, Gloria G. ; Spencer, Brian H. ; Prokaeva, Tatiana B. ; Baldwin, Clinton T. ; Seldin, David C. ; Connors, Lawreen H.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Human genetics, 2015-01, Vol.134 (1), p.111-121
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ArticlesPeer ReviewedFull Text
Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis
Author / Creator:Akar, Harun ; Seldin, David C ; Magnani, Barbarajean ; O'Hara, Carl
Publisher:London: Taylor & Francis Ltd
Journal title:Amyloid, 2005-12, Vol.12 (4), p.210
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ArticlesPeer ReviewedFull Text
A new transthyretin variant (Glu61Gly) associated with cardiomyopathy
Author / Creator:Rosenzweig, Michael ; Skinner, Martha ; Prokaeva, Tatiana ; Théberge, Roger ; Costello, Catherine ; Drachman, Brian M. ; Connors, Lawreen H.
Publisher:England: Informa UK Ltd
Journal title:Amyloid, 2007-03, Vol.14 (1), p.65-71
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ArticlesFull Text
Mapping Cellular Response to Destabilized Transthyretin Reveals Cell- and Amyloidogenic Protein-Specific Signatures
Author / Creator:Ghosh, Sabrina ; Villacorta-Martin, Carlos ; Lindstrom-Vautrin, Jonathan ; Kenney, Devin ; Golden, Carly S ; Edwards, Camille V ; Sanchorawala, Vaishali ; Connors, Lawreen H ; Giadone, Richard M ; Murphy, George James
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2022-08
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Amyloidogenic Proteins Drive Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease
Author / Creator:Giadone, Richard M ; Liberti, Derek C ; Matte, Taylor M ; Rosarda, Jessica D ; Torres-Arancivia, Celia ; Ghosh, Sabrina ; Diedrich, Jolene K ; Pankow, Sandra ; Skvir, Nicholas ; Jyh-Chang, Jean ; Yates, John R ; Wilson, Andrew A ; Connors, Lawreen H ; Kotton, Darrell N ; R Luke Wiseman ; Murphy, George J
Publisher:Cold Spring Harbor: Cold Spring Harbor Laboratory Press
Journal title:bioRxiv, 2019-11
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ArticlesPeer ReviewedFull Text
Preclinical development of siRNA therapeutics for AL amyloidosis
Author / Creator:Hovey, B M ; Ward, J E ; Soo Hoo, P ; O'Hara, C J ; Connors, L H ; Seldin, D C
Publisher:London: Nature Publishing Group UK
Journal title:Gene therapy, 2011-12, Vol.18 (12), p.1150-1156
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Erratum To: Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity
Author / Creator:Guan, Jian ; Mishra, Shikha ; Qiu, Yiling ; Shi, Jianru ; Trudeau, Kyle ; Las, Guy ; Liesa, Marc ; Shirihai, Orian S ; Connors, Lawreen H ; Seldin, David C ; Falk, Rodney H ; MacRae, Calum A ; Liao, Ronglih
Publisher:London: Nature Publishing Group UK
Journal title:EMBO molecular medicine, 2015-05, Vol.7 (5), p.688-688
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ArticlesPeer ReviewedFull Text
Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway
Author / Creator:Shi, Jianru ; Guan, Jian ; Jiang, Bingbing ; Brenner, Daniel A ; Del Monte, Federica ; Ward, Jennifer E ; Connors, Lawreen H ; Sawyer, Douglas B ; Semigran, Marc J ; Macgillivray, Thomas E ; Seldin, David C ; Falk, Rodney ; Liao, Ronglih
Publisher:United States
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4188
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ArticlesPeer ReviewedFull Text
Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38[alpha] MAPK pathway
Author / Creator:Shi, Jianru ; Guan, Jian ; Jiang, Bingbing ; Brenner, Daniel A ; del Monte, Federica ; Ward, Jennifer E ; Connors, Lawreen H ; Sawyer, Douglas B ; Semigran, Marc J ; Macgillivray, Thomas E ; Seldin, David C ; Falk, Rodney ; Liao, Ronglih
Publisher:Washington: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2010-03, Vol.107 (9), p.4188
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Showing 1 to 20 of 24 results

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Marked progress in AL amyloidosis survival: a 40-year longitudinal natural history study

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Features of atrial fibrillation in wild‐type transthyretin cardiac amyloidosis: a systematic review and clinical experience

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Unusual duplication mutation in a surface loop of human transthyretin leads to an aggressive drug-resistant amyloid disease

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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

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Cardiac amyloidosis in African Americans: Comparison of clinical and laboratory features of transthyretin V122I amyloidosis and immunoglobulin light chain amyloidosis

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Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

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Use of Ventilatory Efficiency Slope as a Marker for Increased Mortality in Wild-Type Transthyretin Cardiac Amyloidosis

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Predictors of Mortality in Light Chain Cardiac Amyloidosis with Heart Failure

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Race/ethnicity in systemic AL amyloidosis: perspectives on disease and outcome disparities

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Amyloidogenic Light Chains Induce Cardiomyocyte Contractile Dysfunction and Apoptosis via a Non-Canonical p38α MAPK Pathway

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Stanniocalcin1 is a key mediator of amyloidogenic light chain induced cardiotoxicity

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Genetic variation of the transthyretin gene in wild-type transthyretin amyloidosis (ATTRwt)

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Quantitative serum free light chain assay in the diagnostic evaluation of AL amyloidosis

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A new transthyretin variant (Glu61Gly) associated with cardiomyopathy

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Mapping Cellular Response to Destabilized Transthyretin Reveals Cell- and Amyloidogenic Protein-Specific Signatures

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Amyloidogenic Proteins Drive Hepatic Proteostasis Remodeling in an Induced Pluripotent Stem Cell Model of Systemic Amyloid Disease

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Preclinical development of siRNA therapeutics for AL amyloidosis

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Erratum To: Lysosomal dysfunction and impaired autophagy underlie the pathogenesis of amyloidogenic light chain‐mediated cardiotoxicity

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Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38alpha MAPK pathway

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Amyloidogenic light chains induce cardiomyocyte contractile dysfunction and apoptosis via a non-canonical p38[alpha] MAPK pathway

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