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ArticlesPeer ReviewedFull Text
CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape
Author / Creator:Wang, Gang ; Zhao, Na ; Berkhout, Ben ; Das, Atze T
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy, 2016-03, Vol.24 (3), p.522-526
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CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA
Author / Creator:Binda, Caroline S. ; Klaver, Bep ; Berkhout, Ben ; Das, Atze T.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2020-03, Vol.12 (3), p.330
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ArticlesPeer ReviewedFull Text
Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies
Author / Creator:Darcis, Gilles ; Das, Atze ; Berkhout, Ben
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2018-03, Vol.10 (4), p.157
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ArticlesPeer ReviewedFull Text
HIV co-opts a cellular antiviral mechanism, activation of stress kinase PKR by its RNA, to enable splicing of rev/tat mRNA
Author / Creator:Namer, Lise Sarah ; Harwig, Alex ; Heynen, Stephan P. ; Das, Atze T. ; Berkhout, Ben ; Kaempfer, Raymond
Publisher:England: BioMed Central Ltd
Journal title:Cell & bioscience, 2023-02, Vol.13 (1), p.28-28, Article 28
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ArticlesPeer ReviewedFull Text
Transient CRISPR-Cas Treatment Can Prevent Reactivation of HIV-1 Replication in a Latently Infected T-Cell Line
Author / Creator:Liu, Ye ; Jeeninga, Rienk E. ; Klaver, Bep ; Berkhout, Ben ; Das, Atze T.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2021-12, Vol.13 (12), p.2461
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The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape
Author / Creator:Darcis, Gilles ; Binda, Caroline S. ; Klaver, Bep ; Herrera-Carrillo, Elena ; Berkhout, Ben ; Das, Atze T.
Publisher:Switzerland: MDPI AG
Journal title:Viruses, 2019-03, Vol.11 (3), p.255
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ArticlesPeer ReviewedFull Text
On the generation of the MSD-Ѱ class of defective HIV proviruses
Author / Creator:Das, Atze T. ; Pasternak, Alexander O. ; Berkhout, Ben
Publisher:England: BioMed Central
Journal title:Retrovirology, 2019-07, Vol.16 (1), p.19-19, Article 19
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ArticlesPeer ReviewedFull Text
The Allosteric HIV-1 Integrase Inhibitor BI-D Affects Virion Maturation but Does Not Influence Packaging of a Functional RNA Genome
Author / Creator:van Bel, Nikki ; van der Velden, Yme ; Bonnard, Damien ; Le Rouzic, Erwann ; Das, Atze T. ; Benarous, Richard ; Berkhout, Ben
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-07, Vol.9 (7), p.e103552-e103552
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ArticlesPeer ReviewedFull Text
A Phylogenetic Survey on the Structure of the HIV-1 Leader RNA Domain That Encodes the Splice Donor Signal
Author / Creator:Mueller, Nancy ; Das, Atze ; Berkhout, Ben
Publisher:Switzerland: MDPI
Journal title:Viruses, 2016-07, Vol.8 (7), p.200
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Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine
Author / Creator:Berry, Neil ; Manoussaka, Maria ; Ham, Claire ; Ferguson, Deborah ; Tudor, Hannah ; Mattiuzzo, Giada ; Klaver, Bep ; Page, Mark ; Stebbings, Richard ; Das, Atze T. ; Berkhout, Ben ; Almond, Neil ; Cranage, Martin P.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2016-12, Vol.12 (12), p.e1006083-e1006083
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ArticlesPeer ReviewedFull Text
Variations in the Abortive HIV-1 RNA Hairpin Do Not Impede Viral Sensing and Innate Immune Responses
Author / Creator:Stunnenberg, Melissa ; van Hamme, John L. ; Das, Atze T. ; Berkhout, Ben ; Geijtenbeek, Teunis B. H.
Publisher:Basel: MDPI AG
Journal title:Pathogens (Basel), 2021-07, Vol.10 (7), p.897
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ArticlesPeer ReviewedFull Text
Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging
Author / Creator:Das, Atze T ; Vrolijk, Martine M ; Harwig, Alex ; Berkhout, Ben
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2012-07, Vol.9 (1), p.59-59, Article 59
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ArticlesPeer ReviewedFull Text
A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses
Author / Creator:Chtarto, Abdelwahed ; Humbert-Claude, Marie ; Bockstael, Olivier ; Das, Atze T ; Boutry, Sébastien ; Breger, Ludivine S ; Klaver, Bep ; Melas, Catherine ; Barroso-Chinea, Pedro ; Gonzalez-Hernandez, Tomas ; Muller, Robert N ; DeWitte, Olivier ; Levivier, Marc ; Lundberg, Cecilia ; Berkhout, Ben ; Tenenbaum, Liliane
Publisher:United States: Elsevier Limited
Journal title:Molecular therapy. Methods & clinical development, 2016-01, Vol.3 (C), p.16027-16027, Article 16027
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ArticlesPeer ReviewedFull Text
HIV-1 Escape From RNAi Antivirals: Yet Another Houdini Action?
Author / Creator:Berkhout, Ben ; Das, Atze T
Publisher:United States: Elsevier Inc
Journal title:Molecular therapy. Nucleic acids, 2012-06, Vol.1 (6), p.e26-e26, Article e26
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ArticlesPeer ReviewedFull Text
CRISPR/Cas9: a double-edged sword when used to combat HIV infection
Author / Creator:Liang, Chen ; Wainberg, Mark A. ; Das, Atze T. ; Berkhout, Ben
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2016-05, Vol.13 (1), p.37-37, Article 37
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ArticlesPeer ReviewedFull Text
HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter
Author / Creator:Turrini, Filippo ; Marelli, Sara ; Kajaste-Rudnitski, Anna ; Lusic, Marina ; Van Lint, Carine ; Das, Atze T. ; Harwig, Alex ; Berkhout, Ben ; Vicenzi, Elisa
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2015-12, Vol.12 (1), p.104-104, Article 104
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Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control
Author / Creator:Zhou, Xue ; Vink, Monique ; Berkhout, Ben ; Das, Atze T
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2006-11, Vol.3 (1), p.82-82, Article 82
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ArticlesPeer ReviewedFull Text
Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation
Author / Creator:Vrolijk, Martine M ; Harwig, Alex ; Berkhout, Ben ; Das, Atze T
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2009-02, Vol.6 (1), p.13-13, Article 13
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ArticlesPeer ReviewedFull Text
Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution
Author / Creator:Das, Atze T ; Klaver, Bep ; Centlivre, Mireille ; Harwig, Alex ; Ooms, Marcel ; Page, Mark ; Almond, Neil ; Yuan, Fang ; Piatak, Mike ; Lifson, Jeffrey D ; Berkhout, Ben
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2008-06, Vol.5 (1), p.44-44, Article 44
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ArticlesPeer ReviewedFull Text
On the primer binding site mutation that appears and disappears during HIV and SIV replication
Author / Creator:Berkhout, Ben ; Das, Atze T.
Publisher:England: BioMed Central Ltd
Journal title:Retrovirology, 2015-08, Vol.12 (1), p.75-75, Article 75
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Showing 1 to 20 of 40 results

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CRISPR-Cas9 Can Inhibit HIV-1 Replication but NHEJ Repair Facilitates Virus Escape

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CRISPR-Cas9 Dual-gRNA Attack Causes Mutation, Excision and Inversion of the HIV-1 Proviral DNA

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Tackling HIV Persistence: Pharmacological versus CRISPR-Based Shock Strategies

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HIV co-opts a cellular antiviral mechanism, activation of stress kinase PKR by its RNA, to enable splicing of rev/tat mRNA

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Transient CRISPR-Cas Treatment Can Prevent Reactivation of HIV-1 Replication in a Latently Infected T-Cell Line

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The Impact of HIV-1 Genetic Diversity on CRISPR-Cas9 Antiviral Activity and Viral Escape

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On the generation of the MSD-Ѱ class of defective HIV proviruses

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The Allosteric HIV-1 Integrase Inhibitor BI-D Affects Virion Maturation but Does Not Influence Packaging of a Functional RNA Genome

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A Phylogenetic Survey on the Structure of the HIV-1 Leader RNA Domain That Encodes the Splice Donor Signal

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Role of Occult and Post-acute Phase Replication in Protective Immunity Induced with a Novel Live Attenuated SIV Vaccine

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Variations in the Abortive HIV-1 RNA Hairpin Do Not Impede Viral Sensing and Innate Immune Responses

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Opening of the TAR hairpin in the HIV-1 genome causes aberrant RNA dimerization and packaging

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A regulatable AAV vector mediating GDNF biological effects at clinically-approved sub-antimicrobial doxycycline doses

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HIV-1 Escape From RNAi Antivirals: Yet Another Houdini Action?

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CRISPR/Cas9: a double-edged sword when used to combat HIV infection

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HIV-1 transcriptional silencing caused by TRIM22 inhibition of Sp1 binding to the viral promoter

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Modification of the Tet-On regulatory system prevents the conditional-live HIV-1 variant from losing doxycycline-control

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Destabilization of the TAR hairpin leads to extension of the polyA hairpin and inhibition of HIV-1 polyadenylation

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Optimization of the doxycycline-dependent simian immunodeficiency virus through in vitro evolution

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On the primer binding site mutation that appears and disappears during HIV and SIV replication

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