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24 results for F-Box+Proteins+-+antagonists+

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ArticlesPeer ReviewedFull Text
PTEN counteracts FBXL2 to promote IP3R3- and Ca 2+ -mediated apoptosis limiting tumour growth
Author / Creator:Kuchay, Shafi ; Giorgi, Carlotta ; Simoneschi, Daniele ; Pagan, Julia ; Missiroli, Sonia ; Saraf, Anita ; Florens, Laurence ; Washburn, Michael P ; Collazo-Lorduy, Ana ; Castillo-Martin, Mireia ; Cordon-Cardo, Carlos ; Sebti, Said M ; Pinton, Paolo ; Pagano, Michele
Publisher:England
Journal title:Nature (London), 2017-06, Vol.546 (7659), p.554
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Roles of F-box proteins in cancer
Author / Creator:Wang, Zhiwei ; Liu, Pengda ; Inuzuka, Hiroyuki ; Wei, Wenyi
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Cancer, 2014-04, Vol.14 (4), p.233-247
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SCF ubiquitin ligase-targeted therapies
Author / Creator:Skaar, Jeffrey R. ; Pagan, Julia K. ; Pagano, Michele
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Drug discovery, 2014-12, Vol.13 (12), p.889-903
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F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects
Author / Creator:Tekcham, Dinesh Singh ; Chen, Di ; Liu, Yu ; Ling, Ting ; Zhang, Yi ; Chen, Huan ; Wang, Wen ; Otkur, Wuxiyar ; Qi, Huan ; Xia, Tian ; Liu, Xiaolong ; Piao, Hai-long ; Liu, Hongxu
Publisher:Australia: Ivyspring International Publisher Pty Ltd
Journal title:Theranostics, 2020-01, Vol.10 (9), p.4150-4167
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Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes
Author / Creator:He, Jin ; Shen, Li ; Wan, Ma ; Taranova, Olena ; Wu, Hao ; Zhang, Yi
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2013-04, Vol.15 (4), p.373-384
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Auxin Activates the Plasma Membrane H⁺-ATPase by Phosphorylation during Hypocotyl Elongation in Arabidopsis
Author / Creator:Takahashi, Koji ; Hayashi, Ken-ichiro ; Kinoshita, Toshinori
Publisher:Rockville, MD: American Society of Plant Biologists
Journal title:Plant physiology (Bethesda), 2012-06, Vol.159 (2), p.632-641
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Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1–F-box interface
Author / Creator:Gorelik, Maryna ; Orlicky, Stephen ; Sartori, Maria A. ; Tang, Xiaojing ; Marcon, Edyta ; Kurinov, Igor ; Greenblatt, Jack F. ; Tyers, Mike ; Moffat, Jason ; Sicheri, Frank ; Sidhu, Sachdev S.
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2016-03, Vol.113 (13), p.3527-3532
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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate
Author / Creator:Weiss, Ryan J ; Spahn, Philipp N ; Chiang Austin W T ; Liu, Qing ; Li, Jing ; Hamill, Kristina M ; Rother, Sandra ; Clausen, Thomas M ; Hoeksema, Marten A ; Timm, Bryce M ; Godula Kamil ; Glass, Christopher K ; Tor Yitzhak ; Gordts Philip L S M ; Lewis, Nathan E ; Esko, Jeffrey D
Publisher:Cambridge: Nature Publishing Group
Journal title:Nature chemical biology, 2021-06, Vol.17 (6), p.684-692
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The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication
Author / Creator:Puklowski, Anja ; Homsi, Yahya ; Keller, Debora ; May, Martin ; Chauhan, Sangeeta ; Kossatz, Uta ; Grünwald, Viktor ; Kubicka, Stefan ; Pich, Andreas ; Manns, Michael P. ; Hoffmann, Ingrid ; Gönczy, Pierre ; Malek, Nisar P.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2011-08, Vol.13 (8), p.1004-1009
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Toxoplasma F-box protein 1 is required for daughter cell scaffold function during parasite replication
Author / Creator:Baptista, Carlos Gustavo ; Lis, Agnieszka ; Deng, Bowen ; Gas-Pascual, Elisabet ; Dittmar, Ashley ; Sigurdson, Wade ; West, Christopher M. ; Blader, Ira J.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2019-07, Vol.15 (7), p.e1007946
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Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation
Author / Creator:Delgado-Camprubi, Marta ; Esteras, Noemi ; Soutar, Marc PM ; Plun-Favreau, Helene ; Abramov, Andrey Y
Publisher:London: Nature Publishing Group UK
Journal title:Cell death and differentiation, 2017-01, Vol.24 (1), p.120-131
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Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1α/VEGF pathway
Author / Creator:Zheng, Yufan ; Chen, Hairong ; Zhao, Yang ; Zhang, Xuping ; Liu, Jinjin ; Pan, Yu ; Bai, Jin ; Zhang, Hongwei
Publisher:New York: Springer US
Journal title:Investigational new drugs, 2020-02, Vol.38 (1), p.20-28
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Fbxo30 regulates chromosome segregation of oocyte meiosis
Author / Creator:Jin, Yimei ; Yang, Mo ; Gao, Chang ; Yue, Wei ; Liang, Xiaoling ; Xie, Bingteng ; Zhu, Xiaohui ; Fan, Shangrong ; Li, Rong ; Li, Mo
Publisher:Basel: Springer Nature B.V
Journal title:Cellular and molecular life sciences : CMLS, 2019-06, Vol.76 (11), p.2217-2229
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Blocking the Spinal Fbxo3/CARM1/K+ Channel Epigenetic Silencing Pathway as a Strategy for Neuropathic Pain Relief
Author / Creator:Hsieh, Ming-Chun ; Ho, Yu-Cheng ; Lai, Cheng-Yuan ; Wang, Hsueh-Hsiao ; Yang, Po-Sheng ; Cheng, Jen-Kun ; Chen, Gin-Den ; Ng, Soo-Cheen ; Lee, An-Sheng ; Tseng, Kuang-Wen ; Lin, Tzer-Bin ; Peng, Hsien-Yu
Publisher:Cham: Springer International Publishing
Journal title:Neurotherapeutics, 2021-04, Vol.18 (2), p.1295-1315
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FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression
Author / Creator:Wang, FeiFei ; Xu, HongHai ; YongRong Yan ; Wu, PingXiang ; Wu, JianHua ; Zhu, XiaoHui ; Li, JiaoYing ; Sun, JingBo ; Zhou, Kun ; Ren, XiaoLi ; Lu, Qi ; Lan, XiaoLiang ; Cheng, ZhiQiang ; Tang, Na ; Liao, WenTing ; Ding, YanQing ; Li, Liang
Publisher:London: Springer Nature B.V
Journal title:Cell death & disease, 2019-04, Vol.10 (5)
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ArticlesPeer ReviewedFull Text
Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling
Author / Creator:Hayashi, Ken-ichiro ; Tan, Xu ; Zheng, Ning ; Hatate, Tatsuya ; Kimura, Yoshio ; Kepinski, Stefan ; Nozaki, Hiroshi
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2008-04, Vol.105 (14), p.5632-5637
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FBXL5 Inhibits Metastasis of Gastric Cancer Through Suppressing Snail1
Author / Creator:Wu, Weidong ; Ding, Honghua ; Cao, Jun ; Zhang, Weihao
Publisher:Basel, Switzerland: Cell Physiol Biochem Press GmbH & Co KG
Journal title:Cellular physiology and biochemistry, 2015-01, Vol.35 (5), p.1764-1772
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miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer
Author / Creator:Yan, Meina ; Yang, Xinxin ; Shen, Rong ; Wu, Chengjiang ; Wang, Hui ; Ye, Qing ; Yang, Peifang ; Zhang, Lubin ; Chen, Miao ; Wan, Bing ; Zhang, Qinqin ; Xia, Sheng ; Lu, Xiaodong ; Shao, Genbao ; Zhou, Xiaoming ; Yu, Jun ; Shao, Qixiang
Publisher:London: Nature Publishing Group UK
Journal title:Cell death & disease, 2018-11, Vol.9 (11), p.1123-17, Article 1123
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A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation
Author / Creator:Okabe, Hiroshi ; Lee, Sang-Hyun ; Phuchareon, Janyaporn ; Albertson, Donna G. ; McCormick, Frank ; Tetsu, Osamu
Publisher:United States: Public Library of Science
Journal title:PloS one, 2006-12, Vol.1 (1), p.e128
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FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex
Author / Creator:Sjögren, Benita ; Swaney, Steven ; Neubig, Richard R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-05, Vol.10 (5), p.e0123581
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Showing 1 to 20 of 24 results

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PTEN counteracts FBXL2 to promote IP3R3- and Ca 2+ -mediated apoptosis limiting tumour growth

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Roles of F-box proteins in cancer

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SCF ubiquitin ligase-targeted therapies

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F-box proteins and cancer: an update from functional and regulatory mechanism to therapeutic clinical prospects

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Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

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Auxin Activates the Plasma Membrane H⁺-ATPase by Phosphorylation during Hypocotyl Elongation in Arabidopsis

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Inhibition of SCF ubiquitin ligases by engineered ubiquitin variants that target the Cul1 binding site on the Skp1–F-box interface

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Genome-wide screens uncover KDM2B as a modifier of protein binding to heparan sulfate

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The SCF–FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication

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Toxoplasma F-box protein 1 is required for daughter cell scaffold function during parasite replication

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Deficiency of Parkinson’s disease-related gene Fbxo7 is associated with impaired mitochondrial metabolism by PARP activation

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Knockdown of FBXO22 inhibits melanoma cell migration, invasion and angiogenesis via the HIF-1α/VEGF pathway

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Fbxo30 regulates chromosome segregation of oocyte meiosis

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Blocking the Spinal Fbxo3/CARM1/K+ Channel Epigenetic Silencing Pathway as a Strategy for Neuropathic Pain Relief

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FBX8 degrades GSTP1 through ubiquitination to suppress colorectal cancer progression

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Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling

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FBXL5 Inhibits Metastasis of Gastric Cancer Through Suppressing Snail1

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miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

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A Critical Role for FBXW8 and MAPK in Cyclin D1 Degradation and Cancer Cell Proliferation

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FBXO44-Mediated Degradation of RGS2 Protein Uniquely Depends on a Cullin 4B/DDB1 Complex

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