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157 results for Fatty+Liver+-+enzymology

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Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis
Author / Creator:Dai, Jianye ; Liang, Kai ; Zhao, Shan ; Jia, Wentong ; Liu, Yuan ; Wu, Hongkun ; Lv, Jia ; Cao, Chen ; Chen, Tao ; Zhuang, Shentian ; Hou, Xiaomeng ; Zhou, Shijie ; Zhang, Xiannian ; Chen, Xiao-Wei ; 陈晓伟 ; Huang, Yanyi ; Xiao, Rui-Ping ; Wang, Yan-Ling ; Luo, Tuoping ; Xiao, Junyu ; Wang, Chu
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (26), p.E5896-E5905
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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease
Author / Creator:Emdin, Connor A. ; Haas, Mary E. ; Khera, Amit V. ; Aragam, Krishna ; Chaffin, Mark ; Klarin, Derek ; Hindy, George ; Jiang, Lan ; Wei, Wei-Qi ; Feng, Qiping ; Karjalainen, Juha ; Havulinna, Aki ; Kiiskinen, Tuomo ; Bick, Alexander ; Ardissino, Diego ; Wilson, James G. ; Schunkert, Heribert ; McPherson, Ruth ; Watkins, Hugh ; Elosua, Roberto ; Bown, Matthew J. ; Samani, Nilesh J. ; Baber, Usman ; Erdmann, Jeanette ; Gupta, Namrata ; Danesh, John ; Saleheen, Danish ; Chang, Kyong-Mi ; Vujkovic, Marijana ; Voight, Ben ; Damrauer, Scott ; Lynch, Julie ; Kaplan, David ; Serper, Marina ; Tsao, Philip ; Mercader, Josep ; Hanis, Craig ; Daly, Mark ; Denny, Joshua ; Gabriel, Stacey ; Kathiresan, Sekar
Publisher:United States: Public Library of Science
Journal title:PLoS genetics, 2020-04, Vol.16 (4), p.e1008629
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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
Author / Creator:Schweiger, Martina ; Romauch, Matthias ; Schreiber, Renate ; Grabner, Gernot F. ; Hütter, Sabrina ; Kotzbeck, Petra ; Benedikt, Pia ; Eichmann, Thomas O. ; Yamada, Sohsuke ; Knittelfelder, Oskar ; Diwoky, Clemens ; Doler, Carina ; Mayer, Nicole ; De Cecco, Werner ; Breinbauer, Rolf ; Zimmermann, Robert ; Zechner, Rudolf
Publisher:London: Nature Publishing Group UK
Journal title:Nature communications, 2017-03, Vol.8 (1), p.14859-14859, Article 14859
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Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease
Author / Creator:Su, Wen ; Wang, Yang ; Jia, Xiao ; Wu, Wenhan ; Li, Linghai ; Tian, Xiaodong ; Li, Sha ; Wang, Chunjiong ; Xu, Huamin ; Cao, Jiaqi ; Han, Qifei ; Xu, Shimeng ; Chen, Yong ; Zhong, Yanfeng ; Zhang, Xiaoyan ; Liu, Pingsheng ; Gustafsson, Jan-Åke ; Guan, Youfei
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2014-08, Vol.111 (31), p.11437-11442
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Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C
Author / Creator:Miquilena-Colina, María Eugenia ; Lima-Cabello, Elena ; Sánchez-Campos, Sonia ; García-Mediavilla, María Victoria ; Fernández-Bermejo, Miguel ; Lozano-Rodríguez, Tamara ; Vargas-Castrillón, Javier ; Buqué, Xabier ; Ochoa, Begoña ; Aspichueta, Patricia ; González-Gallego, Javier ; García-Monzón, Carmelo
Publisher:London: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2011-10, Vol.60 (10), p.1394-1402
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The emerging role of E3 ubiquitin ligases and deubiquitinases in metabolic dysfunction-associated steatotic liver disease
Author / Creator:Zhang, Yu ; Yang, Jiahui ; Min, Jiali ; Huang, Shan ; Li, Yuchen ; Liu, Shanshan
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2025-03, Vol.23 (1), p.368-27, Article 368
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ATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis
Author / Creator:Slusher, Aaron L. ; Santoro, Nicola ; Vash-Margita, Alla ; Galderisi, Alfonso ; Hu, Pamela ; Tokoglu, Fuyuze ; Li, Zhongyao ; Tarabra, Elena ; Strober, Jordan ; Vatner, Daniel F. ; Shulman, Gerald I. ; Caprio, Sonia
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2025-03, Vol.135 (6), p.1-8
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Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver
Author / Creator:Lanaspa, Miguel A. ; Cicerchi, Christina ; Garcia, Gabriela ; Li, Nanxing ; Roncal-Jimenez, Carlos A. ; Rivard, Christopher J. ; Hunter, Brandi ; Andrés-Hernando, Ana ; Ishimoto, Takuji ; Sánchez-Lozada, Laura G. ; Thomas, Jeffrey ; Hodges, Robert S. ; Mant, Colin T. ; Johnson, Richard J.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-11, Vol.7 (11), p.e48801-e48801
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Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis
Author / Creator:Dixon, Laura J. ; Flask, Chris A. ; Papouchado, Bettina G. ; Feldstein, Ariel E. ; Nagy, Laura E.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-02, Vol.8 (2), p.e56100-e56100
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O -GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver
Author / Creator:Guinez, Céline ; Filhoulaud, Gaëlle ; Rayah-Benhamed, Fadila ; Marmier, Solenne ; Dubuquoy, Céline ; Dentin, Renaud ; Moldes, Marthe ; Burnol, Anne-Françoise ; Yang, Xiaoyong ; Lefebvre, Tony ; Girard, Jean ; Postic, Catherine
Publisher:United States: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2011-05, Vol.60 (5), p.1399-1413
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Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance
Author / Creator:Kumashiro, Naoki ; Beddow, Sara A. ; Vatner, Daniel F. ; Majumdar, Sachin K. ; Cantley, Jennifer L. ; Guebre-Egziabher, Fitsum ; Fat, Ioana ; Guigni, Blas ; Jurczak, Michael J. ; Birkenfeld, Andreas L. ; Kahn, Mario ; Perler, Bryce K. ; Puchowicz, Michelle A. ; Manchem, Vara Prasad ; Bhanot, Sanjay ; Still, Christopher D. ; Gerhard, Glenn S. ; Petersen, Kitt Falk ; Cline, Gary W. ; Shulman, Gerald I. ; Samuel, Varman T.
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2013-07, Vol.62 (7), p.2183-2194
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MiR-451a attenuates hepatic steatosis and hepatitis C virus replication by targeting glycerol kinase
Author / Creator:Majumdar, Swagata ; Chowdhury, Deeya Roy ; Chakraborty, Bidhan Chandra ; Chowdhury, Abhijit ; Datta, Simanti ; Banerjee, Soma
Publisher:England: BioMed Central Ltd
Journal title:Journal of translational medicine, 2025-03, Vol.23 (1), p.322-12, Article 322
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A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects
Author / Creator:Lee, Jae Man ; Lee, Yoon Kwang ; Mamrosh, Jennifer L. ; Busby, Scott A. ; Griffin, Patrick R. ; Pathak, Manish C. ; Ortlund, Eric A. ; Moore, David D.
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2011-06, Vol.474 (7352), p.506-510
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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2
Author / Creator:Savage, D. B.
Publisher:United States: American Society for Clinical Investigation
Journal title:The Journal of clinical investigation, 2006-03, Vol.116 (3), p.817-824
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Caspase 3 Inactivation Protects Against Hepatic Cell Death and Ameliorates Fibrogenesis in a Diet-Induced NASH Model
Author / Creator:Thapaliya, Samjhana ; Wree, Alexander ; Povero, Davide ; Inzaugarat, Maria Eugenia ; Berk, Michael ; Dixon, Laura ; Papouchado, Bettina G. ; Feldstein, Ariel E.
Publisher:Boston: Springer US
Journal title:Digestive diseases and sciences, 2014-06, Vol.59 (6), p.1197-1206
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The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease
Author / Creator:Schuck, Robert N. ; Zha, Weibin ; Edin, Matthew L. ; Gruzdev, Artiom ; Vendrov, Kimberly C. ; Miller, Tricia M. ; Xu, Zhenghong ; Lih, Fred B. ; DeGraff, Laura M. ; Tomer, Kenneth B. ; Jones, H. Michael ; Makowski, Liza ; Huang, Leaf ; Poloyac, Samuel M. ; Zeldin, Darryl C. ; Lee, Craig R.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2014-10, Vol.9 (10), p.e110162
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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis
Author / Creator:Leone, Teresa C ; Lehman, John J ; Finck, Brian N ; Schaeffer, Paul J ; Wende, Adam R ; Boudina, Sihem ; Courtois, Michael ; Wozniak, David F ; Sambandam, Nandakumar ; Bernal-Mizrachi, Carlos ; Chen, Zhouji ; Holloszy, John O ; Medeiros, Denis M ; Schmidt, Robert E ; Saffitz, Jeffrey E ; Abel, E Dale ; Semenkovich, Clay F ; Kelly, Daniel P
Publisher:United States: Public Library of Science (PLoS)
Journal title:PLoS biology, 2005-04, Vol.3 (4), p.e101-e101
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Neutrophil-Derived Myeloperoxidase Aggravates Non-Alcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Deficient Mice
Author / Creator:Rensen, Sander S. ; Bieghs, Veerle ; Xanthoulea, Sofia ; Arfianti, Evi ; Bakker, Jaap A. ; Shiri-Sverdlov, Ronit ; Hofker, Marten H. ; Greve, Jan Willem ; Buurman, Wim A.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2012-12, Vol.7 (12), p.e52411
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The Prevalence and Etiology of Elevated Aminotransferase Levels in The United States
Author / Creator:Clark, Jeanne M ; Brancati, Frederick L ; Diehl, Anna Mae
Publisher:Oxford: .
Journal title:The American journal of gastroenterology, 2003-05, Vol.98 (5), p.960-967
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Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver
Author / Creator:Kotronen, Anna ; Seppänen-Laakso, Tuulikki ; Westerbacka, Jukka ; Kiviluoto, Tuula ; Arola, Johanna ; Ruskeepää, Anna-Liisa ; Orešič, Matej ; Yki-Järvinen, Hannele
Publisher:Alexandria, VA: American Diabetes Association
Journal title:Diabetes (New York, N.Y.), 2009-01, Vol.58 (1), p.203-208
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Showing 1 to 20 of 157 results

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Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis

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A missense variant in Mitochondrial Amidoxime Reducing Component 1 gene and protection against liver disease

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Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice

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Comparative proteomic study reveals 17β-HSD13 as a pathogenic protein in nonalcoholic fatty liver disease

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Hepatic fatty acid translocase CD36 upregulation is associated with insulin resistance, hyperinsulinaemia and increased steatosis in non-alcoholic steatohepatitis and chronic hepatitis C

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The emerging role of E3 ubiquitin ligases and deubiquitinases in metabolic dysfunction-associated steatotic liver disease

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ATGL links insulin dysregulation to insulin resistance in adolescents with obesity and hepatosteatosis

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Counteracting Roles of AMP Deaminase and AMP Kinase in the Development of Fatty Liver

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Caspase-1 as a Central Regulator of High Fat Diet-Induced Non-Alcoholic Steatohepatitis

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O -GlcNAcylation Increases ChREBP Protein Content and Transcriptional Activity in the Liver

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Targeting Pyruvate Carboxylase Reduces Gluconeogenesis and Adiposity and Improves Insulin Resistance

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MiR-451a attenuates hepatic steatosis and hepatitis C virus replication by targeting glycerol kinase

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A nuclear-receptor-dependent phosphatidylcholine pathway with antidiabetic effects

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Reversal of diet-induced hepatic steatosis and hepatic insulin resistance by antisense oligonucleotide inhibitors of acetyl-CoA carboxylases 1 and 2

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Caspase 3 Inactivation Protects Against Hepatic Cell Death and Ameliorates Fibrogenesis in a Diet-Induced NASH Model

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The Cytochrome P450 Epoxygenase Pathway Regulates the Hepatic Inflammatory Response in Fatty Liver Disease

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PGC-1alpha deficiency causes multi-system energy metabolic derangements: muscle dysfunction, abnormal weight control and hepatic steatosis

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Neutrophil-Derived Myeloperoxidase Aggravates Non-Alcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Deficient Mice

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The Prevalence and Etiology of Elevated Aminotransferase Levels in The United States

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Hepatic Stearoyl-CoA Desaturase (SCD)-1 Activity and Diacylglycerol but Not Ceramide Concentrations Are Increased in the Nonalcoholic Human Fatty Liver

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