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73 results for Filaricides+-+pharmacology

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Progress towards onchocerciasis elimination in the participating countries of the African Programme for Onchocerciasis Control: epidemiological evaluation results
Author / Creator:Tekle, Afework H. ; Zouré, Honorath G. M. ; Noma, Mounkaila ; Boussinesq, Michel ; Coffeng, Luc E. ; Stolk, Wilma A. ; Remme, Jan H. F.
Publisher:England: BioMed Central Ltd
Journal title:Infectious diseases of poverty, 2016-06, Vol.5 (1), p.66-66, Article 66
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The endosymbiont Wolbachia rebounds following antibiotic treatment
Author / Creator:Gunderson, Emma L. ; Vogel, Ian ; Chappell, Laura ; Bulman, Christina A. ; Lim, K. C. ; Luo, Mona ; Whitman, Jeffrey D. ; Franklin, Chris ; Choi, Young-Jun ; Lefoulon, Emilie ; Clark, Travis ; Beerntsen, Brenda ; Slatko, Barton ; Mitreva, Makedonka ; Sullivan, William ; Sakanari, Judy A.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2020-07, Vol.16 (7), p.e1008623
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Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis
Author / Creator:TAYLOR, MARK J. ; HOERAUF, ACHIM ; TOWNSON, SIMON ; SLATKO, BARTON E. ; WARD, STEPHEN A.
Publisher:Cambridge, UK: Cambridge University Press
Journal title:Parasitology, 2014-01, Vol.141 (1), p.119-127
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Lymphatic filariasis endgame strategies: Using GEOFIL to model mass drug administration and targeted surveillance and treatment strategies in American Samoa
Author / Creator:Shaw, Callum ; McLure, Angus ; Graves, Patricia M. ; Lau, Colleen L. ; Glass, Kathryn
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2023-05, Vol.17 (5), p.e0011347-e0011347
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Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery
Author / Creator:Ayiseh, Rene Bilingwe ; Mbah, Glory Enjong ; Monya, Elvis ; Ndi, Emmanuel Menang ; Sakanari, Judy ; Lustigman, Sara ; Cho-Ngwa, Fidelis
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2023-02, Vol.17 (2), p.e0011135-e0011135
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Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity
Author / Creator:von Geldern, Thomas W. ; Morton, Howard E. ; Clark, Rick F. ; Brown, Brian S. ; Johnston, Kelly L. ; Ford, Louise ; Specht, Sabine ; Carr, Robert A. ; Stolarik, Deanne F. ; Ma, Junli ; Rieser, Matthew J. ; Struever, Dominique ; Frohberger, Stefan J. ; Koschel, Marianne ; Ehrens, Alexandra ; Turner, Joseph D. ; Hübner, Marc P. ; Hoerauf, Achim ; Taylor, Mark J. ; Ward, Stephen A. ; Marsh, Kennan ; Kempf, Dale J.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-02, Vol.13 (2), p.e0007159
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Discovery of potent inhibitors targeting Glutathione S-transferase of Wuchereria bancrofti: a step toward the development of effective anti-filariasis drugs
Author / Creator:Sureshan, Muthusamy ; Prabhu, Dhamodharan ; Rajamanikandan, Sundarraj ; Saraboji, Kadhirvel
Publisher:Cham: Springer International Publishing
Journal title:Molecular diversity, 2024-04, Vol.28 (2), p.765-785
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Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal
Author / Creator:O'Connell, Elise M. ; Bennuru, Sasisekhar ; Steel, Cathy ; Dolan, Michael A. ; Nutman, Thomas B.
Publisher:United States: Oxford University Press
Journal title:The Journal of infectious diseases, 2015-09, Vol.212 (5), p.684-693
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Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel
Author / Creator:Kashyap, Sudhanva S. ; Verma, Saurabh ; Voronin, Denis ; Lustigman, Sara ; Kulke, Daniel ; Robertson, Alan P. ; Martin, Richard J.
Publisher:United States: Public Library of Science
Journal title:PLoS pathogens, 2019-09, Vol.15 (9), p.e1008041-e1008041
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Radioprotective effect of diethylcarbamazine on radiation-induced acute lung injury and oxidative stress in mice
Author / Creator:Farzipour, Soghra ; Amiri, Fereshteh Talebpour ; Mihandoust, Ehsan ; Shaki, Fatemeh ; Noaparast, Zohreh ; Ghasemi, Arash ; Hosseinimehr, Seyed Jalal
Publisher:New York: Springer US
Journal title:Journal of bioenergetics and biomembranes, 2020-02, Vol.52 (1), p.39-46
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Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds
Author / Creator:Hübner, Marc P. ; Ehrens, Alexandra ; Koschel, Marianne ; Dubben, Bettina ; Lenz, Franziska ; Frohberger, Stefan J. ; Specht, Sabine ; Quirynen, Ludo ; Lachau-Durand, Sophie ; Tekle, Fetene ; Baeten, Benny ; Engelen, Marc ; Mackenzie, Charles D. ; Hoerauf, Achim
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-01, Vol.13 (1), p.e0006320
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Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?
Author / Creator:Maclean, Mary J. ; Savadelis, Molly D. ; Coates, Ruby ; Dzimianski, Michael T. ; Jones, Corey ; Benbow, Cynthia ; Storey, Bobby E. ; Kaplan, Ray M. ; Moorhead, Andrew R. ; Wolstenholme, Adrian J.
Publisher:England: BioMed Central Ltd
Journal title:Parasites & vectors, 2017-11, Vol.10 (S2), p.480-480, Article 480
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Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets
Author / Creator:Curran, David M ; Grote, Alexandra ; Nursimulu, Nirvana ; Geber, Adam ; Voronin, Dennis ; Jones, Drew R ; Ghedin, Elodie ; Parkinson, John
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2020-08, Vol.9
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Influence of autophagy, apoptosis and their interplay in filaricidal activity of C-cinnamoyl glycosides
Author / Creator:Roy, Priya ; Sengupta, Anirban ; Joardar, Nikhilesh ; Bhattacharyya, Arindam ; Saha, Nimai Chandra ; Misra, Anup Kumar ; Sinha Babu, Santi P.
Publisher:Cambridge, UK: Cambridge University Press
Journal title:Parasitology, 2019-09, Vol.146 (11), p.1451-1461
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Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents
Author / Creator:Twumasi, Emmanuella Bema ; Akazue, Pearl Ihuoma ; Kyeremeh, Kwaku ; Gwira, Theresa Manful ; Keiser, Jennifer ; Cho-Ngwa, Fidelis ; Flint, Adrian ; Anibea, Barbara ; Bonsu, Emmanuel Yeboah ; Amewu, Richard K. ; Amoah, Linda Eva ; Appiah-Opong, Regina ; Osei-Safo, Dorcas
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2020-12, Vol.14 (12), p.e0008919-e0008919
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Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo
Author / Creator:Schiefer, Andrea ; Schmitz, Alexander ; Schäberle, Till F. ; Specht, Sabine ; Lämmer, Christine ; Johnston, Kelly L ; Vassylyev, Dmitry G. ; König, Gabriele M. ; Hoerauf, Achim ; Pfarr, Kenneth
Publisher:Oxford: Oxford University Press
Journal title:The Journal of infectious diseases, 2012-07, Vol.206 (2), p.249-257
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Polyphenol enriched ethanolic extract of Cajanus scarabaeoides (L.) Thouars exerts potential antifilarial activity by inducing oxidative stress and programmed cell death
Author / Creator:Ray, Anindya Sundar ; Joardar, Nikhilesh ; Mukherjee, Suprabhat ; Rahaman, Chowdhury Habibur ; Sinha Babu, Santi P.
Publisher:United States: Public Library of Science
Journal title:PloS one, 2018-12, Vol.13 (12), p.e0208201
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Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models
Author / Creator:Sjoberg, Hanna T. ; Pionnier, Nicolas ; Aljayyoussi, Ghaith ; Metuge, Haelly M. ; Njouendou, Abdel J. ; Chunda, Valerine C. ; Fombad, Fanny F. ; Tayong, Dizzle B. ; Gandjui, Narcisse V. T. ; Akumtoh, Desmond N. ; Chounna, Patrick W. N. ; Ndzeshang, Bertrand L. ; Lachaud, Sophie ; Tekle, Fetene ; Quirynen, Ludo ; Engelen, Marc ; Baeten, Benny ; Steven, Andrew ; Ward, Stephen A. ; Taylor, Mark J. ; Wanji, Samuel ; Turner, Joseph D.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2019-01, Vol.13 (1), p.e0006356-e0006356
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Creative use of the priority review voucher by public and not-for-profit actors delivers the first new FDA-approved treatment for river blindness in 20 years
Author / Creator:Olliaro, Piero L. ; Kuesel, Annette C. ; Halleux, Christine M. ; Sullivan, Mark ; Reeder, John C.
Publisher:United States: Public Library of Science
Journal title:PLoS neglected tropical diseases, 2018-11, Vol.12 (11), p.e0006837
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Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives
Author / Creator:Bourguinat, Catherine ; Keller, Kathy ; Xia, Jianguo ; Lepage, Pierre ; McTier, Tom L. ; Woods, Debra J. ; Prichard, Roger K.
Publisher:England: BioMed Central Ltd
Journal title:Parasites & vectors, 2017-11, Vol.10 (S2), p.504-504, Article 504
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Showing 1 to 20 of 73 results

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Progress towards onchocerciasis elimination in the participating countries of the African Programme for Onchocerciasis Control: epidemiological evaluation results

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The endosymbiont Wolbachia rebounds following antibiotic treatment

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Anti-Wolbachia drug discovery and development: safe macrofilaricides for onchocerciasis and lymphatic filariasis

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Lymphatic filariasis endgame strategies: Using GEOFIL to model mass drug administration and targeted surveillance and treatment strategies in American Samoa

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Development and validation of small animal models for onchocerciasis and loiasis microfilaricide discovery

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Discovery of ABBV-4083, a novel analog of Tylosin A that has potent anti-Wolbachia and anti-filarial activity

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Discovery of potent inhibitors targeting Glutathione S-transferase of Wuchereria bancrofti: a step toward the development of effective anti-filariasis drugs

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Targeting Filarial Abl-like Kinases: Orally Available, Food and Drug Administration-Approved Tyrosine Kinase Inhibitors Are Microfilaricidal and Macrofilaricidal

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Emodepside has sex-dependent immobilizing effects on adult Brugia malayi due to a differentially spliced binding pocket in the RCK1 region of the SLO-1 K channel

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Radioprotective effect of diethylcarbamazine on radiation-induced acute lung injury and oxidative stress in mice

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Macrofilaricidal efficacy of single and repeated oral and subcutaneous doses of flubendazole in Litomosoides sigmodontis infected jirds

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Does evaluation of in vitro microfilarial motility reflect the resistance status of Dirofilaria immitis isolates to macrocyclic lactones?

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Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets

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Influence of autophagy, apoptosis and their interplay in filaricidal activity of C-cinnamoyl glycosides

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Antischistosomal, antionchocercal and antitrypanosomal potentials of some Ghanaian traditional medicines and their constituents

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Corallopyronin A Specifically Targets and Depletes Essential Obligate Wolbachia Endobacteria From Filarial Nematodes In Vivo

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Polyphenol enriched ethanolic extract of Cajanus scarabaeoides (L.) Thouars exerts potential antifilarial activity by inducing oxidative stress and programmed cell death

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Short-course, oral flubendazole does not mediate significant efficacy against Onchocerca adult male worms or Brugia microfilariae in murine infection models

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Creative use of the priority review voucher by public and not-for-profit actors delivers the first new FDA-approved treatment for river blindness in 20 years

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Genetic profiles of ten Dirofilaria immitis isolates susceptible or resistant to macrocyclic lactone heartworm preventives

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