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210 results for Genes,+erbB-2+-+genetics

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ArticlesPeer ReviewedFull Text
Comprehensive molecular portraits of human breast tumours
Author / Creator:Prat Aparicio, Aleix
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2012-10, Vol.490 (7418), p.61-70
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ArticlesPeer ReviewedFull Text
Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart
Author / Creator:Honkoop, Hessel ; de Bakker, Dennis Em ; Aharonov, Alla ; Kruse, Fabian ; Shakked, Avraham ; Nguyen, Phong D ; de Heus, Cecilia ; Garric, Laurence ; Muraro, Mauro J ; Shoffner, Adam ; Tessadori, Federico ; Peterson, Joshua Craiger ; Noort, Wendy ; Bertozzi, Alberto ; Weidinger, Gilbert ; Posthuma, George ; Grün, Dominic ; van der Laarse, Willem J ; Klumperman, Judith ; Jaspers, Richard T ; Poss, Kenneth D ; van Oudenaarden, Alexander ; Tzahor, Eldad ; Bakkers, Jeroen
Publisher:England: eLife Sciences Publications Ltd
Journal title:eLife, 2019-12, Vol.8
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Treatment of HER2-positive breast cancer: current status and future perspectives
Author / Creator:Arteaga, Carlos L. ; Sliwkowski, Mark X. ; Osborne, C. Kent ; Perez, Edith A. ; Puglisi, Fabio ; Gianni, Luca
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2012-01, Vol.9 (1), p.16-32
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ArticlesPeer ReviewedFull Text
Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a rand...
Author / Creator:Gianni, Luca, Dr ; Eiermann, Wolfgang, MD ; Semiglazov, Vladimir, MD ; Manikhas, Alexey, MD ; Lluch, Ana, MD ; Tjulandin, Sergey, MD ; Zambetti, Milvia, MD ; Vazquez, Federico, MD ; Byakhow, Mikhail, MD ; Lichinitser, Mikhail, MD ; Climent, Miguel Angel, MD ; Ciruelos, Eva, MD ; Ojeda, Belén, MD ; Mansutti, Mauro, MD ; Bozhok, Alla, MD ; Baronio, Roberta, MSci ; Feyereislova, Andrea, MD ; Barton, Claire, MD ; Valagussa, Pinuccia ; Baselga, Jose, MD
Publisher:Kidlington: Elsevier Ltd
Journal title:The Lancet (British edition), 2010-01, Vol.375 (9712), p.377-384
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ArticlesPeer ReviewedFull Text
PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia
Author / Creator:Banh, Robert S. ; Iorio, Caterina ; Marcotte, Richard ; Xu, Yang ; Cojocari, Dan ; Rahman, Anas Abdel ; Pawling, Judy ; Zhang, Wei ; Sinha, Ankit ; Rose, Christopher M. ; Isasa, Marta ; Zhang, Shuang ; Wu, Ronald ; Virtanen, Carl ; Hitomi, Toshiaki ; Habu, Toshiyuki ; Sidhu, Sachdev S. ; Koizumi, Akio ; Wilkins, Sarah E. ; Kislinger, Thomas ; Gygi, Steven P. ; Schofield, Christopher J. ; Dennis, James W. ; Wouters, Bradly G. ; Neel, Benjamin G.
Publisher:London: Nature Publishing Group UK
Journal title:Nature cell biology, 2016-07, Vol.18 (7), p.803-813
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ArticlesPeer ReviewedFull Text
Intratumoral heterogeneity of HER2 gene amplification in breast cancer: its clinicopathological significance
Author / Creator:Seol, Hyesil ; Lee, Hyun Ju ; Choi, Yoomi ; Lee, Hee Eun ; Kim, Yu Jung ; Kim, Jee Hyun ; Kang, Eunyoung ; Kim, Sung-Won ; Park, So Yeon
Publisher:New York: Elsevier Inc
Journal title:Modern pathology, 2012-07, Vol.25 (7), p.938-948
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ArticlesPeer ReviewedFull Text
HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer
Author / Creator:Lee, Hee Jin ; Seo, An Na ; Kim, Eun Joo ; Jang, Min Hye ; Suh, Koung Jin ; Ryu, Han Suk ; Kim, Yu Jung ; Kim, Jee Hyun ; Im, Seock-Ah ; Gong, Gyungyub ; Jung, Kyung Hae ; Park, In Ae ; Park, So Yeon
Publisher:England: Oxford University Press
Journal title:American journal of clinical pathology, 2014-12, Vol.142 (6), p.755-766
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ArticlesPeer ReviewedFull Text
Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizum...
Author / Creator:von Minckwitz, Gunter, Prof ; Puglisi, Fabio, MD ; Cortes, Javier, MD ; Vrdoljak, Eduard, Prof ; Marschner, Norbert, MD ; Zielinski, Christoph, Prof ; Villanueva, Cristian, MD ; Romieu, Gilles, MD ; Lang, István, Prof ; Ciruelos, Eva, MD ; De Laurentiis, Michele, MD ; Veyret, Corinne, Prof ; de Ducla, Sabine, DEA ; Freudensprung, Ulrich, MSc ; Srock, Stefanie, MD ; Gligorov, Joseph, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2014-10, Vol.15 (11), p.1269-1278
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ArticlesPeer ReviewedFull Text
Efficacy and safety of pyrotinib in advanced lung adenocarcinoma with HER2 mutations: a multicenter, single-arm, phase II trial
Author / Creator:Song, Zhengbo ; Li, Yuping ; Chen, Shiqing ; Ying, Shenpeng ; Xu, Shuguang ; Huang, Jianjin ; Wu, Dan ; Lv, Dongqing ; Bei, Ting ; Liu, Shuxun ; Huang, Xiaoping ; Xie, Congying ; Wu, Xiaoyu ; Fu, Jianfei ; Hua, Feng ; Wang, Wenxian ; Xu, Chunwei ; Gao, Chan ; Cai, Shangli ; Lu, Shun ; Zhang, Yiping
Publisher:England: BioMed Central Ltd
Journal title:BMC medicine, 2022-02, Vol.20 (1), p.42-42, Article 42
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ArticlesPeer ReviewedFull Text
Practical implications of gene-expression-based assays for breast oncologists
Author / Creator:Prat, Aleix ; Ellis, Matthew J. ; Perou, Charles M.
Publisher:London: Nature Publishing Group UK
Journal title:Nature reviews. Clinical oncology, 2012-01, Vol.9 (1), p.48-57
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ArticlesPeer ReviewedFull Text
Correlation of HER2 status between primary tumors and corresponding circulating tumor cells in advanced breast cancer patients
Author / Creator:Pestrin, Marta ; Bessi, Silvia ; Galardi, Francesca ; Truglia, Mara ; Biggeri, Annibale ; Biagioni, Chiara ; Cappadona, Silvia ; Biganzoli, Laura ; Giannini, Augusto ; Di Leo, Angelo
Publisher:Boston: Boston : Springer US
Journal title:Breast cancer research and treatment, 2009-12, Vol.118 (3), p.523-530
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ArticlesPeer ReviewedFull Text
Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen
Author / Creator:Hurtado, Antoni ; Holmes, Kelly A. ; Geistlinger, Timothy R. ; Hutcheson, Iain R. ; Nicholson, Robert I. ; Brown, Myles ; Jiang, Jie ; Howat, William J. ; Ali, Simak ; Carroll, Jason S.
Publisher:London: Nature Publishing Group UK
Journal title:Nature, 2008-12, Vol.456 (7222), p.663-666
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ArticlesPeer ReviewedFull Text
Clinicopathologic Significance of the Intratumoral Heterogeneity of HER2 Gene Amplification in HER2-Positive Breast Cancer Patients Treated With Adjuvant Trastuzumab
Author / Creator:Lee, Hee Jin ; Kim, Joo Young ; Park, So Yeon ; Park, In Ah ; Song, In Hye ; Yu, Jong Han ; Ahn, Jin-Hee ; Gong, Gyungyub
Publisher:Oxford, UK: Oxford University Press
Journal title:American journal of clinical pathology, 2015-10, Vol.144 (4), p.570-578
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ArticlesPeer ReviewedFull Text
Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study
Author / Creator:Gong, Yun, Dr ; Yan, Kai, MS ; Lin, Feng, MD ; Anderson, Keith, MS ; Sotiriou, Christos, MD ; Andre, Fabrice, MD ; Holmes, Frankie A, MD ; Valero, Vicente, Prof ; Booser, Daniel, Prof ; Pippen, John E, MD ; Vukelja, Svetislava, MD ; Gomez, Henry, MD ; Mejia, Jaime, MD ; Barajas, Luis J, MD ; Hess, Kenneth R, PhD ; Sneige, Nour, Prof ; Hortobagyi, Gabriel N, Prof ; Pusztai, Lajos, MD ; Symmans, W Fraser, MD
Publisher:England: Elsevier Ltd
Journal title:The lancet oncology, 2007-03, Vol.8 (3), p.203-211
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ArticlesPeer ReviewedFull Text
Impact of the 2013 ASCO/CAP HER2 Guideline Updates at an Academic Medical Center That Performs Primary HER2 FISH Testing: Increase in Equivocal Results and Utility of Reflex Immunohistochemistry
Author / Creator:Muller, Kristen E ; Marotti, Jonathan D ; Memoli, Vincent A ; Wells, Wendy A ; Tafe, Laura J
Publisher:England
Journal title:American journal of clinical pathology, 2015-08, Vol.144 (2), p.247-252
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ArticlesPeer ReviewedFull Text
Identification of valid reference genes for the normalization of RT-qPCR expression studies in human breast cancer cell lines treated with and without transient transfection
Author / Creator:Liu, Lin-Lin ; Zhao, Hui ; Ma, Teng-Fei ; Ge, Fei ; Chen, Ce-Shi ; Zhang, Ya-Ping
Publisher:United States: Public Library of Science
Journal title:PloS one, 2015-01, Vol.10 (1), p.e0117058-e0117058
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ArticlesPeer ReviewedFull Text
HER-2 Gene Amplification Can Be Acquired as Breast Cancer Progresses
Author / Creator:Meng, Songdong ; Tripathy, Debasish ; Shete, Sanjay ; Ashfaq, Raheela ; Haley, Barbara ; Perkins, Steve ; Beitsch, Peter ; Khan, Amanullah ; Euhus, David ; Osborne, Cynthia ; Frenkel, Eugene ; Hoover, Susan ; Leitch, Marilyn ; Clifford, Edward ; Vitetta, Ellen ; Morrison, Larry ; Herlyn, Dorothee ; Leon W. M. M. Terstappen ; Fleming, Timothy ; Fehm, Tanja ; Tucker, Thomas ; Lane, Nancy ; Wang, Jianqiang ; Uhr, Jonathan
Publisher:United States: National Academy of Sciences
Journal title:Proceedings of the National Academy of Sciences - PNAS, 2004-06, Vol.101 (25), p.9393-9398
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ArticlesPeer ReviewedFull Text
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis
Author / Creator:Thayer, Sarah P. ; di Magliano, Marina Pasca ; Heiser, Patrick W. ; Nielsen, Corinne M. ; Roberts, Drucilla J. ; Lauwers, Gregory Y. ; Qi, Yan Ping ; Gysin, Stephan ; Castillo, Carlos Fernández-del ; Yajnik, Vijay ; Antoniu, Bozena ; McMahon, Martin ; Warshaw, Andrew L. ; Hebrok, Matthias
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2003-10, Vol.425 (6960), p.851-856
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ArticlesPeer ReviewedFull Text
Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification
Author / Creator:Durst, Franziska C ; Grujovic, Ana ; Ganser, Iris ; Hoffmann, Martin ; Ugocsai, Peter ; Klein, Christoph A ; Czyż, Zbigniew T
Publisher:United States: Public Library of Science
Journal title:PloS one, 2019-08, Vol.14 (8), p.e0216442
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ArticlesPeer ReviewedFull Text
Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer
Author / Creator:Flores, L M ; Kindelberger, D W ; Ligon, A H ; Capelletti, M ; Fiorentino, M ; Loda, M ; Cibas, E S ; Jänne, P A ; Krop, I E
Publisher:London: Nature Publishing Group UK
Journal title:British journal of cancer, 2010-05, Vol.102 (10), p.1495-1502
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Comprehensive molecular portraits of human breast tumours

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Single-cell analysis uncovers that metabolic reprogramming by ErbB2 signaling is essential for cardiomyocyte proliferation in the regenerating heart

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Treatment of HER2-positive breast cancer: current status and future perspectives

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Neoadjuvant chemotherapy with trastuzumab followed by adjuvant trastuzumab versus neoadjuvant chemotherapy alone, in patients with HER2-positive locally advanced breast cancer (the NOAH trial): a rand...

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PTP1B controls non-mitochondrial oxygen consumption by regulating RNF213 to promote tumour survival during hypoxia

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Intratumoral heterogeneity of HER2 gene amplification in breast cancer: its clinicopathological significance

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HER2 heterogeneity affects trastuzumab responses and survival in patients with HER2-positive metastatic breast cancer

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Bevacizumab plus chemotherapy versus chemotherapy alone as second-line treatment for patients with HER2-negative locally recurrent or metastatic breast cancer after first-line treatment with bevacizum...

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Efficacy and safety of pyrotinib in advanced lung adenocarcinoma with HER2 mutations: a multicenter, single-arm, phase II trial

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Practical implications of gene-expression-based assays for breast oncologists

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Correlation of HER2 status between primary tumors and corresponding circulating tumor cells in advanced breast cancer patients

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Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen

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Clinicopathologic Significance of the Intratumoral Heterogeneity of HER2 Gene Amplification in HER2-Positive Breast Cancer Patients Treated With Adjuvant Trastuzumab

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Determination of oestrogen-receptor status and ERBB2 status of breast carcinoma: a gene-expression profiling study

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Impact of the 2013 ASCO/CAP HER2 Guideline Updates at an Academic Medical Center That Performs Primary HER2 FISH Testing: Increase in Equivocal Results and Utility of Reflex Immunohistochemistry

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Identification of valid reference genes for the normalization of RT-qPCR expression studies in human breast cancer cell lines treated with and without transient transfection

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HER-2 Gene Amplification Can Be Acquired as Breast Cancer Progresses

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Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis

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Targeted transcript quantification in single disseminated cancer cells after whole transcriptome amplification

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Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer

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