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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma
Author / Creator:Mazur, Pawel K ; Herner, Alexander ; Mello, Stephano S ; Wirth, Matthias ; Hausmann, Simone ; Sánchez-Rivera, Francisco J ; Lofgren, Shane M ; Kuschma, Timo ; Hahn, Stephan A ; Vangala, Deepak ; Trajkovic-Arsic, Marija ; Gupta, Aayush ; Heid, Irina ; Noël, Peter B ; Braren, Rickmer ; Erkan, Mert ; Kleeff, Jörg ; Sipos, Bence ; Sayles, Leanne C ; Heikenwalder, Mathias ; Heßmann, Elisabeth ; Ellenrieder, Volker ; Esposito, Irene ; Jacks, Tyler ; Bradner, James E ; Khatri, Purvesh ; Sweet-Cordero, E Alejandro ; Attardi, Laura D ; Schmid, Roland M ; Schneider, Guenter ; Sage, Julien ; Siveke, Jens T
Publisher:New York: Nature Publishing Group US
Journal title:Nature medicine, 2015-10, Vol.21 (10), p.1163-1171
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Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling
Author / Creator:Zimmermann, Gunther ; Papke, Björn ; Ismail, Shehab ; Vartak, Nachiket ; Chandra, Anchal ; Hoffmann, Maike ; Hahn, Stephan A. ; Triola, Gemma ; Wittinghofer, Alfred ; Bastiaens, Philippe I. H. ; Waldmann, Herbert
Publisher:London: Nature Publishing Group UK
Journal title:Nature (London), 2013-05, Vol.497 (7451), p.638-642
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A genetic roadmap of pancreatic cancer: still evolving
Author / Creator:Notta, Faiyaz ; Hahn, Stephan A ; Real, Francisco X
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2017-12, Vol.66 (12), p.2170-2178
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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer
Author / Creator:Gout, Johann ; Perkhofer, Lukas ; Morawe, Mareen ; Arnold, Frank ; Ihle, Michaela ; Biber, Stephanie ; Lange, Sebastian ; Roger, Elodie ; Kraus, Johann M ; Stifter, Katja ; Hahn, Stephan A ; Zamperone, Andrea ; Engleitner, Thomas ; Müller, Martin ; Walter, Karolin ; Rodriguez-Aznar, Eva ; Sainz Jr, Bruno ; Hermann, Patrick C ; Hessmann, Elisabeth ; Müller, Sebastian ; Azoitei, Ninel ; Lechel, André ; Liebau, Stefan ; Wagner, Martin ; Simeone, Diane M ; Kestler, Hans A ; Seufferlein, Thomas ; Wiesmüller, Lisa ; Rad, Roland ; Frappart, Pierre-Olivier ; Kleger, Alexander
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2021-04, Vol.70 (4), p.743-760
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Cytotoxicity of CD19-CAR-NK92 cells is primarily mediated via perforin/granzyme pathway
Author / Creator:Althaus, Jonas ; Nilius-Eliliwi, Verena ; Maghnouj, Abdelouahid ; Döring, Sascha ; Schroers, Roland ; Hudecek, Michael ; Hahn, Stephan A. ; Mika, Thomas
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:Cancer Immunology, Immunotherapy, 2023-08, Vol.72 (8), p.2573-2583
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Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases, and benign melanocytic nevi
Author / Creator:Sand, Michael ; Skrygan, Marina ; Sand, Daniel ; Georgas, Dimitrios ; Gambichler, Thilo ; Hahn, Stephan A ; Altmeyer, Peter ; Bechara, Falk G
Publisher:Berlin/Heidelberg: Springer-Verlag
Journal title:Cell and tissue research, 2013-01, Vol.351 (1), p.85-98
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Circular RNA expression in basal cell carcinoma
Author / Creator:Sand, Michael ; Bechara, Falk G ; Sand, Daniel ; Gambichler, Thilo ; Hahn, Stephan A ; Bromba, Michael ; Stockfleth, Eggert ; Hessam, Schapoor
Publisher:England: Future Medicine Ltd
Journal title:Epigenomics, 2016-05, Vol.8 (5), p.619-632
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Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells
Author / Creator:Birkenkamp-Demtröder, Karin ; Hahn, Stephan A. ; Mansilla, Francisco ; Thorsen, Kasper ; Maghnouj, Abdelouahid ; Christensen, Rikke ; Øster, Bodil ; Ørntoft, Torben Falck
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-09, Vol.8 (9), p.e73593-e73593
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Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis
Author / Creator:Weber, Lea ; Al-Refae, Klaudia ; Ebbert, Juliane ; Jägers, Peter ; Altmüller, Janine ; Becker, Christian ; Hahn, Stephan ; Gisselmann, Günter ; Hatt, Hanns
Publisher:United States: Public Library of Science
Journal title:PloS one, 2017-03, Vol.12 (3), p.e0172491-e0172491
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MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B
Author / Creator:Liffers, Sven-T ; Munding, Johanna B ; Vogt, Markus ; Kuhlmann, Jan D ; Verdoodt, Berlinda ; Nambiar, Sandeep ; Maghnouj, Abdelouahid ; Mirmohammadsadegh, Alireza ; Hahn, Stephan A ; Tannapfel, Andrea
Publisher:New York: Elsevier Inc
Journal title:Laboratory investigation, 2011-10, Vol.91 (10), p.1472-1479
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Repeatability and reproducibility of ADC measurements: a prospective multicenter whole-body-MRI study
Author / Creator:Michoux, Nicolas F. ; Ceranka, Jakub W. ; Vandemeulebroucke, Jef ; Peeters, Frank ; Lu, Pierre ; Absil, Julie ; Triqueneaux, Perrine ; Liu, Yan ; Collette, Laurence ; Willekens, Inneke ; Brussaard, Carola ; Debeir, Olivier ; Hahn, Stephan ; Raeymaekers, Hubert ; de Mey, Johan ; Metens, Thierry ; Lecouvet, Frédéric E.
Publisher:Berlin/Heidelberg: Springer Berlin Heidelberg
Journal title:European radiology, 2021-07, Vol.31 (7), p.4514-4527
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Circulating U2 Small Nuclear RNA Fragments as a Novel Diagnostic Tool for Patients with Epithelial Ovarian Cancer
Author / Creator:Kuhlmann, Jan Dominik ; Baraniskin, Alexander ; Hahn, Stephan A ; Mosel, Frank ; Bredemeier, Maren ; Wimberger, Pauline ; Kimmig, Rainer ; Kasimir-Bauer, Sabine
Publisher:England: Oxford University Press
Journal title:Clinical chemistry (Baltimore, Md.), 2014-01, Vol.60 (1), p.206-213
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Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors
Author / Creator:Mavrommatis, Lampros ; Jeong, Hyun-Woo ; Kindler, Urs ; Gomez-Giro, Gemma ; Kienitz, Marie-Cecile ; Stehling, Martin ; Psathaki, Olympia E ; Zeuschner, Dagmar ; Bixel, M Gabriele ; Han, Dong ; Morosan-Puopolo, Gabriela ; Gerovska, Daniela ; Yang, Ji Hun ; Kim, Jeong Beom ; Arauzo-Bravo, Marcos J ; Schwamborn, Jens C ; Hahn, Stephan A ; Adams, Ralf H ; Schöler, Hans R ; Vorgerd, Matthias ; Brand-Saberi, Beate ; Zaehres, Holm
Publisher:Cambridge: eLife Science Publications, Ltd
Journal title:eLife, 2023-11, Vol.12
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A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling
Author / Creator:Kong, Bo ; Wu, Weiwei ; Cheng, Tao ; Schlitter, Anna Melissa ; Qian, Chengjia ; Bruns, Philipp ; Jian, Ziying ; Jäger, Carsten ; Regel, Ivonne ; Raulefs, Susanne ; Behler, Nora ; Irmler, Martin ; Beckers, Johannes ; Friess, Helmut ; Erkan, Mert ; Siveke, Jens T ; Tannapfel, Andrea ; Hahn, Stephan A ; Theis, Fabian J ; Esposito, Irene ; Kleeff, Jörg ; Michalski, Christoph W
Publisher:England: BMJ Publishing Group LTD
Journal title:Gut, 2016-04, Vol.65 (4), p.647-657
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Blood‐based detection of RAS mutations to guide anti‐EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue‐based RAS testing
Author / Creator:Schmiegel, Wolff ; Scott, Rodney J. ; Dooley, Susan ; Lewis, Wendy ; Meldrum, Cliff J. ; Pockney, Peter ; Draganic, Brian ; Smith, Steve ; Hewitt, Chelsee ; Philimore, Hazel ; Lucas, Amanda ; Shi, Elva ; Namdarian, Kateh ; Chan, Timmy ; Acosta, Danilo ; Ping‐Chang, Su ; Tannapfel, Andrea ; Reinacher‐Schick, Anke ; Uhl, Waldemar ; Teschendorf, Christian ; Wolters, Heiner ; Stern, Josef ; Viebahn, Richard ; Friess, Helmut ; Janssen, Klaus‐Peter ; Nitsche, Ulrich ; Slotta‐Huspenina, Julia ; Pohl, Michael ; Vangala, Deepak ; Baraniskin, Alexander ; Dockhorn‐Dworniczak, Barbara ; Hegewisch‐Becker, Susanne ; Ronga, Philippe ; Edelstein, Daniel L. ; Jones, Frederick S. ; Hahn, Stephan ; Fox, Stephen B.
Publisher:United States: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2017-02, Vol.11 (2), p.208-219
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Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts
Author / Creator:Hermann, Patrick C. ; Trabulo, Sara M. ; Sainz, Bruno ; Balic, Anamaria ; Garcia, Elena ; Hahn, Stephan A. ; Vandana, Mallaredy ; Sahoo, Sanjeeb K. ; Tunici, Patrizia ; Bakker, Annette ; Hidalgo, Manuel ; Heeschen, Christopher
Publisher:United States: Public Library of Science
Journal title:PloS one, 2013-06, Vol.8 (6), p.e66371
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Lasting response by vertical inhibition with cetuximab and trametinib in KRAS ‐mutated colorectal cancer patient‐derived xenografts
Author / Creator:Reissig, Timm M. ; Ladigan‐Badura, Swetlana ; Steinberg, Anja ; Maghnouj, Abdelouahid ; Li, Ting ; Verdoodt, Berlinda ; Liffers, Sven T. ; Pohl, Michael ; Wolters, Heiner ; Teschendorf, Christian ; Viebahn, Richard ; Admard, Jakob ; Casadei, Nicolas ; Tannapfel, Andrea ; Schmiegel, Wolff ; Hahn, Stephan A. ; Vangala, Deepak B.
Publisher:Hoboken: John Wiley & Sons, Inc
Journal title:Molecular oncology, 2023-11, Vol.17 (11), p.2396-2414
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Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer
Author / Creator:Hamdan, Feda H ; Abdelrahman, Amro M ; Kutschat, Ana Patricia ; Wang, Xin ; Ekstrom, Thomas L ; Jalan-Sakrikar, Nidhi ; Wegner Wippel, Catherine ; Taheri, Negar ; Tamon, Liezel ; Kopp, Waltraut ; Aggrey-Fynn, Joana ; Bhagwate, Aditya V ; Alva-Ruiz, Roberto ; Lynch, Isaac ; Yonkus, Jennifer ; Kosinsky, Robyn Laura ; Gaedcke, Jochen ; Hahn, Stephan A ; Siveke, Jens T ; Graham, Rondell ; Najafova, Zeynab ; Hessmann, Elisabeth ; Truty, Mark J ; Johnsen, Steven A
Publisher:England: BMJ Publishing Group Ltd and British Society of Gastroenterology
Journal title:Gut, 2023-06, Vol.72 (6), p.1174-1185
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ArticlesPeer ReviewedFull Text
MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma
Author / Creator:Baraniskin, Alexander ; Kuhnhenn, Jan ; Schlegel, Uwe ; Schmiegel, Wolf ; Hahn, Stephan ; Schroers, Roland
Publisher:Boston: Springer US
Journal title:Journal of neuro-oncology, 2012-09, Vol.109 (2), p.239-244
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Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level
Author / Creator:Hammoud, Mohamad K. ; Yosef, Hesham K. ; Lechtonen, Tatjana ; Aljakouch, Karim ; Schuler, Martin ; Alsaidi, Wissam ; Daho, Ibrahim ; Maghnouj, Abdelouahid ; Hahn, Stephan ; El-Mashtoly, Samir F. ; Gerwert, Klaus
Publisher:London: Nature Publishing Group UK
Journal title:Scientific reports, 2018-10, Vol.8 (1), p.15278-11, Article 15278
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Showing 1 to 20 of 86 results

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Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma

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Small molecule inhibition of the KRAS–PDEδ interaction impairs oncogenic KRAS signalling

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A genetic roadmap of pancreatic cancer: still evolving

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Synergistic targeting and resistance to PARP inhibition in DNA damage repair-deficient pancreatic cancer

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Cytotoxicity of CD19-CAR-NK92 cells is primarily mediated via perforin/granzyme pathway

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Comparative microarray analysis of microRNA expression profiles in primary cutaneous malignant melanoma, cutaneous malignant melanoma metastases, and benign melanocytic nevi

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Circular RNA expression in basal cell carcinoma

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Keratin23 (KRT23) Knockdown Decreases Proliferation and Affects the DNA Damage Response of Colon Cancer Cells

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Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis

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MicroRNA-148a is down-regulated in human pancreatic ductal adenocarcinomas and regulates cell survival by targeting CDC25B

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Repeatability and reproducibility of ADC measurements: a prospective multicenter whole-body-MRI study

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Circulating U2 Small Nuclear RNA Fragments as a Novel Diagnostic Tool for Patients with Epithelial Ovarian Cancer

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Human skeletal muscle organoids model fetal myogenesis and sustain uncommitted PAX7 myogenic progenitors

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A subset of metastatic pancreatic ductal adenocarcinomas depends quantitatively on oncogenic Kras/Mek/Erk-induced hyperactive mTOR signalling

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Blood‐based detection of RAS mutations to guide anti‐EGFR therapy in colorectal cancer patients: concordance of results from circulating tumor DNA and tissue‐based RAS testing

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Multimodal Treatment Eliminates Cancer Stem Cells and Leads to Long-Term Survival in Primary Human Pancreatic Cancer Tissue Xenografts

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Lasting response by vertical inhibition with cetuximab and trametinib in KRAS ‐mutated colorectal cancer patient‐derived xenografts

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Interactive enhancer hubs (iHUBs) mediate transcriptional reprogramming and adaptive resistance in pancreatic cancer

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MicroRNAs in cerebrospinal fluid as biomarker for disease course monitoring in primary central nervous system lymphoma

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Raman micro-spectroscopy monitors acquired resistance to targeted cancer therapy at the cellular level

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